Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Julian C. Bahr"'
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Cancer cells and macrophages can infiltrate and remodel the extracellular matrix (ECM). Here, by using native basement membrane-interstitial matrix explants as model and live cell confocal imaging, the authors reveal divergent mechanisms used by canc
Externí odkaz:
https://doaj.org/article/1a7670873a1c4f749a9b3b628cb103ce
Publikováno v:
Nature communications. 13(1)
Macrophages and cancer cells populations are posited to navigate basement membrane barriers by either mobilizing proteolytic enzymes or deploying mechanical forces. Nevertheless, the relative roles, or identity, of the proteinase -dependent or -indep
Autor:
Robert W. Robey, Arup R. Chakraborty, Joel P. Schneider, Agnes Basseville, Susan E. Bates, Gary T. Pauly, Julian C. Bahr, Hanna Kozlowski, Paresma Patel, Victoria Luchenko, Michael M. Gottesman
Publikováno v:
Oncotarget
// Julian C. Bahr 1, * , Robert W. Robey 1, 2, * , Victoria Luchenko 1 , Agnes Basseville 1 , Arup R. Chakraborty 1 , Hanna Kozlowski 2 , Gary T. Pauly 3 , Paresma Patel 3 , Joel P. Schneider 3 , Michael M. Gottesman 2 , Susan E. Bates 1, 4 1 Develop
Autor:
Julian C. Bahr, Guang Liang, Ri Cui, Nicola Zanesi, Huijun Wei, Carlo M. Croce, Wei Meng, Zhenghua Luo
H-RasV12 oncogene has been shown to promote autophagic cell death. Here, we provide evidence of a contextual role for H-RasV12 in cell death that is varied by its effects on miR-130a. In E1A-immortalized murine embryo fibroblasts, acute expression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ae3b3fc48fa45b1af29ba9df73fc73d
https://europepmc.org/articles/PMC7081380/
https://europepmc.org/articles/PMC7081380/
Autor:
Daniel T. Eitzman, Takeshi Akama, Richard H. Barnes, Julian C. Bahr, Miina K. Öhman, Stephen J. Weiss, Tae Hwa Chun, Moon Sook Woo
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The MMP (matrix metalloproteinase) family plays diverse and critical roles in directing vascular wall remodeling in atherosclerosis. Unlike secreted‐type MMP s, a member of the membrane‐type MMP family, MT 1‐ MMP (membrane‐type 1 M
Publikováno v:
Drug Transporters: Molecular Characterization and Role in Drug Disposition, Second Edition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13c22328d419ae99c2bbc42ddf2f2d5a
https://doi.org/10.1002/9781118705308.ch11
https://doi.org/10.1002/9781118705308.ch11
Autor:
Caterina Ieranò, Arup R. Chakraborty, Alina Nicolae, Stefania Pittaluga, Zhirong Zhan, Robert W. Robey, Susan E. Bates, Julian C. Bahr
Publikováno v:
Cell cycle (Georgetown, Tex.). 12(17)
Burkitt lymphoma is characterized by deregulation of c-myc, and therapies targeting c-myc are under investigation as treatments. Histone deacetylase inhibitors are known to abrogate c-myc expression, leading us to examine their effect in a series of
Autor:
Agnes Basseville, Robert W. Robey, Arup R. Chakraborty, Zhirong Zhan, Julian C. Bahr, Susan E. Bates, Victoria Luchenko
The histone deacetylase inhibitors (HDIs) have shown promise in the treatment of a number of hematologic malignancies, leading to the approval of vorinostat and romidepsin for the treatment of cutaneous T-cell lymphoma and romidepsin for the treatmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e728c09ffbe32565707dd0bf430e6a5
https://europepmc.org/articles/PMC3230675/
https://europepmc.org/articles/PMC3230675/
Autor:
Robert W. Robey, Tomasz Obrzut, Orsolya Polgar, Suneet Shukla, Attilio Di Pietro, Suresh V. Ambudkar, Julian C. Bahr, Susan E. Bates, Sira Macalou
ABCG2 overexpression has been linked to resistance to topoisomerase inhibitors, leading us to examine the potential interaction between ABCG2 and becatecarin.Interaction with ABCG2 was determined by ATPase assay, competition of [(125)I]iodoarylazidop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfccdaffff31d6902544e4e8c197b7b5
https://europepmc.org/articles/PMC2693460/
https://europepmc.org/articles/PMC2693460/
Autor:
Agnes Basseville, Andrew J. McDonald, Julian C. Bahr, Victoria Luchenko, Susan E. Bates, Robert W. Robey, Alexandra S Zimmer, Arup R. Chakraborty, Richard Piekarz
Publikováno v:
Cancer Research. 74:5536-5536
In ongoing efforts to increase the solid tumor efficacy of the histone deacetylase inhibitor romidepsin, we characterized romidepsin-resistant T-cell lymphoma cell lines that were found to have activation of the mitogen-activated protein kinase (MAPK