Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Julian C van Capelleveen"'
Autor:
Stephanie Maiwald, Suthesh Sivapalaratnam, Mahdi M Motazacker, Julian C van Capelleveen, Ilze Bot, Saskia C de Jager, Miranda van Eck, Jennifer Jolley, Johan Kuiper, Jonathon Stephens, Cornelius A Albers, C Ruben Vosmeer, Heleen Kruize, Daan P Geerke, Allard C van der Wal, Chris M van der Loos, John J P Kastelein, Mieke D Trip, Willem H Ouwehand, Geesje M Dallinga-Thie, G Kees Hovingh
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e98289 (2014)
Genetic factors explain a proportion of the inter-individual variation in the risk for atherosclerotic events, but the genetic basis of atherosclerosis and atherothrombosis in families with Mendelian forms of premature atherosclerosis is incompletely
Externí odkaz:
https://doaj.org/article/d0ef6506d4f4491a80ea2afb192bac40
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 9, Pp 1612-1618 (2016)
Lipoprotein (a) [Lp(a)] is a human plasma lipoprotein with unique structural and functional characteristics. Lp(a) is an assembly of two components: a central core with apoB and an additional glycoprotein, called apo(a). Ever since the strong associa
Externí odkaz:
https://doaj.org/article/cfd332c59ef84ecdba3093b30a155a2d
Autor:
Julian C. van Capelleveen, Andrea E. Bochem, S. Matthijs Boekholdt, Samia Mora, Ron C. Hoogeveen, Christie M. Ballantyne, Paul M Ridker, Wensheng Sun, Philip J. Barter, Alan R. Tall, Aeilko H. Zwinderman, John J. P. Kastelein, Nick J. Wareham, Kay‐Tee Khaw, G. Kees Hovingh
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 8 (2017)
BackgroundThe contribution of apolipoprotein A‐I (apoA‐I) to coronary heart disease (CHD) risk stratification over and above high‐density lipoprotein cholesterol (HDL‐C) is unclear. We studied the associations between plasma levels of HDL‐C
Externí odkaz:
https://doaj.org/article/3670d413f04b444b99bb4c8cbffc9cae
Autor:
G. Kees Hovingh, Caroline S. Bruikman, Julian C. van Capelleveen, Geesje M. Dallinga-Thie, Laurens C. Huisman, Onno J. de Boer, Anne Tybjærg-Hansen, Jorge Peter, Martine C.M. Willems, Jeffrey Kroon, N. Dalila, Stefan R. Havik
Publikováno v:
Journal of clinical lipidology, 14(4), 470-481. Elsevier BV
Background Genetic factors partly determine the risk for premature myocardial infarction (MI). Objectives We report the identification of a novel rare genetic variant in a kindred with an autosomal dominant trait for premature MI and atherosclerosis
Autor:
Bart van de Sluis, Geesje M. Dallinga-Thie, Richard J. Sinke, Federico Oldoni, N. Dalila, Jan Albert Kuivenhoven, Justina C. Wolters, Julian C. van Capelleveen, David Y. Hui, Joerg Heeren, Kees Hovingh, Ruth Frikke-Schmidt, Anne Tybjærg-Hansen
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology, 38(7), 1440-1453. Lippincott Williams and Wilkins
Arteriosclerosis, Thrombosis, and Vascular Biology
Arteriosclerosis, thrombosis, and vascular biology, 38(7), 1440-1453. LIPPINCOTT WILLIAMS & WILKINS
Arteriosclerosis, Thrombosis, and Vascular Biology
Arteriosclerosis, thrombosis, and vascular biology, 38(7), 1440-1453. LIPPINCOTT WILLIAMS & WILKINS
Supplemental Digital Content is available in the text.
Objective— Studies into the role of LRP1 (low-density lipoprotein receptor–related protein 1) in human lipid metabolism are scarce. Although it is known that a common variant in LRP1 (rs
Objective— Studies into the role of LRP1 (low-density lipoprotein receptor–related protein 1) in human lipid metabolism are scarce. Although it is known that a common variant in LRP1 (rs
Autor:
Joseph L. Witztum, Rosie Z. Yu, Julian C. van Capelleveen, Mark J. Graham, Erik S.G. Stroes, Stanley T. Crooke, Sotirios Tsimikas, Rosanne M. Crooke, Nicholas J. Viney, Shuting Xia, Joseph A. Tami, Santica M. Marcovina, Richard S. Geary, Steven G. Hughes
Publikováno v:
Lancet, 388(10057), 2239-2253. Elsevier Limited
Summary Background Elevated lipoprotein(a) (Lp[a]) is a highly prevalent (around 20% of people) genetic risk factor for cardiovascular disease and calcific aortic valve stenosis, but no approved specific therapy exists to substantially lower Lp(a) co
Autor:
Stephanie Maiwald, Suthesh Sivapalaratnam, G. Kees Hovingh, Geesje M. Dallinga-Thie, M. Mahdi Motazacker, John J.P. Kastelein, Jaap D. van Buul, Allard C. van der Wal, Julian C. van Capelleveen, Chris M. van der Loos, Mieke D. Trip, Willem H. Ouwehand
Publikováno v:
European journal of human genetics, 24(1), 86-91. Nature Publishing Group
Cardiovascular disease (CVD) is a major cause of death in Western societies. CVD risk is largely genetically determined. The molecular pathology is, however, not elucidated in a large number of families suffering from CVD. We applied exclusion linkag
Autor:
Caroline S Bruikman, Dianne Vreeken, Julian C van Capelleveen, Huayu Zhang, Sara J Pinto-Sietsma, Geesje M Dallinga-Thie, G. K Hovingh, Janine M van Gils
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38
Introduction: Neuroimmune guidance cues (NGCs), a family of proteins originally known for controlling neuronal migration, have been shown to be involved in atherosclerosis in mice models by regulating adhesion of monocytes to the vascular endothelium
Autor:
Joseph L. Witztum, S. Matthijs Boekholdt, Sang-Rok Lee, G. Kees Hovingh, John J.P. Kastelein, Julian C. van Capelleveen, Nicholas J. Wareham, Kay-Tee Khaw, Erik S.G. Stroes, Sotirios Tsimikas, Rutger Verbeek
Publikováno v:
Journal of clinical lipidology, 12(6), 1493-1501.e11. Elsevier BV
Journal of clinical lipidology, vol 12, iss 6
Journal of clinical lipidology, vol 12, iss 6
BackgroundPlasma apolipoprotein C-III (apoC-III) levels are associated with coronary artery disease (CAD) risk.ObjectiveTo assess whether lipoprotein-associated apoC-III levels predict risk of CAD events.MethodsapoC-III associated with apoB, apoAI, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95807192fe60e06d6f30aadd4cbfcb41
https://pure.amc.nl/en/publications/relationship-of-lipoproteinassociated-apolipoprotein-ciii-with-lipid-variables-and-coronary-artery-disease-risk-the-epicnorfolk-prospective-population-study(500dc511-739e-46da-b27d-887fa826700c).html
https://pure.amc.nl/en/publications/relationship-of-lipoproteinassociated-apolipoprotein-ciii-with-lipid-variables-and-coronary-artery-disease-risk-the-epicnorfolk-prospective-population-study(500dc511-739e-46da-b27d-887fa826700c).html
Publikováno v:
Current Opinion in Lipidology. 25:418-422
Purpose of review Recent large Mendelian randomization studies associate loss-of-function mutations in apolipoprotein CIII (APOCIII) with low levels of triglycerides and decreased incidence of cardiovascular disease. With ample in-vitro and in-vivo e