Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Julian Buchrieser"'
Autor:
Nell Saunders, Blandine Monel, Nadège Cayet, Lorenzo Archetti, Hugo Moreno, Alexandre Jeanne, Agathe Marguier, Julian Buchrieser, Timothy Wai, Olivier Schwartz, Mathieu Fréchin
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Assessing the impact of SARS-CoV-2 on organelle dynamics allows a better understanding of the mechanisms of viral replication. We combine label-free holotomographic microscopy with Artificial Intelligence to visualize and quantify the subcel
Externí odkaz:
https://doaj.org/article/0a5c18c6b4274149b0ffa8dbec5050a9
Autor:
Delphine Planas, Isabelle Staropoli, Vincent Michel, Frederic Lemoine, Flora Donati, Matthieu Prot, Francoise Porrot, Florence Guivel-Benhassine, Banujaa Jeyarajah, Angela Brisebarre, Océane Dehan, Léa Avon, William Henry Bolland, Mathieu Hubert, Julian Buchrieser, Thibault Vanhoucke, Pierre Rosenbaum, David Veyer, Hélène Péré, Bruno Lina, Sophie Trouillet-Assant, Laurent Hocqueloux, Thierry Prazuck, Etienne Simon-Loriere, Olivier Schwartz
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The unceasing circulation of SARS-CoV-2 leads to the continuous emergence of novel viral sublineages. Here, we isolate and characterize XBB.1, XBB.1.5, XBB.1.9.1, XBB.1.16.1, EG.5.1.1, EG.5.1.3, XBF, BA.2.86.1 and JN.1 variants, representing
Externí odkaz:
https://doaj.org/article/8234f50bbc5043a1a52a4adceb8cfad0
Autor:
Séverine A. Degrelle, Julian Buchrieser, Anne Dupressoir, Françoise Porrot, Laurence Loeuillet, Olivier Schwartz, Thierry Fournier
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107147- (2023)
Summary: Interferon-induced transmembrane proteins (IFITMs) are restriction factors that block many viruses from entering cells. High levels of type I interferon (IFN) are associated with adverse pregnancy outcomes, and IFITMs have been shown to impa
Externí odkaz:
https://doaj.org/article/3800e4dfae434e5faad3c4f224226faa
Autor:
Mathieu Claireaux, Rémy Robinot, Jérôme Kervevan, Mandar Patgaonkar, Isabelle Staropoli, Anne Brelot, Alexandre Nouël, Stacy Gellenoncourt, Xian Tang, Mélanie Héry, Stevenn Volant, Emeline Perthame, Véronique Avettand-Fenoël, Julian Buchrieser, Thomas Cokelaer, Christiane Bouchier, Laurence Ma, Faroudy Boufassa, Samia Hendou, Valentina Libri, Milena Hasan, David Zucman, Pierre de Truchis, Olivier Schwartz, Olivier Lambotte, Lisa A. Chakrabarti
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Here, Claireaux et al. show that people who naturally control HIV infection express lower levels of the viral co-receptor CCR5 in specific CD4+ T cells, and that this results from mutations or receptor internalization by CD4+ T cell-produced chemokin
Externí odkaz:
https://doaj.org/article/e28895a87b7e41c89703ad60c628fffd
Autor:
Charlotte Martinat, Arthur Cormier, Joëlle Tobaly-Tapiero, Noé Palmic, Nicoletta Casartelli, Bijan Mahboubi, Si’Ana A. Coggins, Julian Buchrieser, Mirjana Persaud, Felipe Diaz-Griffero, Lucile Espert, Guillaume Bossis, Pascale Lesage, Olivier Schwartz, Baek Kim, Florence Margottin-Goguet, Ali Saïb, Alessia Zamborlini
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
SAMHD1 is a cellular dNTPase proposed to inhibit HIV-1 reverse transcription in non-cycling immune cells by limiting dNTP substrate supply; its anti-viral but not dNTPase function is downregulated by phosphorylation of T592. Here, Martinat et al. des
Externí odkaz:
https://doaj.org/article/70d02ba8c29446d69d93dada293f5c11
Autor:
Emeline Bonsergent, Eleonora Grisard, Julian Buchrieser, Olivier Schwartz, Clotilde Théry, Grégory Lavieu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Extracellular vesicles mediate cell–cell communication, however, their capacity to deliver their content within acceptor cells is unclear. Here, the authors develop a quantitative assay and show that release of extracellular vesicle contents requir
Externí odkaz:
https://doaj.org/article/ece2db4046514778818273a46db0be84
Autor:
Nell Saunders, Delphine Planas, William H. Bolland, Christophe Rodriguez, Slim Fourati, Julian Buchrieser, Cyril Planchais, Matthieu Prot, Isabelle Staropoli, Florence Guivel-Benhassine, Françoise Porrot, David Veyer, Hélène Péré, Nicolas Robillard, Madelina Saliba, Artem Baidaliuk, Aymeric Seve, Laurent Hocqueloux, Thierry Prazuck, Felix A. Rey, Hugo Mouquet, Etienne Simon-Lorière, Timothée Bruel, Jean-Michel Pawlotsky, Olivier Schwartz
Publikováno v:
EBioMedicine, Vol 77, Iss , Pp 103934- (2022)
Summary: Background: SARS-CoV-2 lineages are continuously evolving. As of December 2021, the AY.4.2 Delta sub-lineage represented 20 % of sequenced strains in the UK and had been detected in dozens of countries. It has since then been supplanted by O
Externí odkaz:
https://doaj.org/article/4dfcddff1cd1483b863fbf185e40d85f
Autor:
Jan Hellert, Julian Buchrieser, Florence Larrous, Andrea Minola, Guilherme Dias de Melo, Leah Soriaga, Patrick England, Ahmed Haouz, Amalio Telenti, Olivier Schwartz, Davide Corti, Hervé Bourhy, Félix A. Rey
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Rabies virus (RABV) infection of unvaccinated individuals can be treated with post exposure prophylaxis. Here, Hellert et al. analyze the structure of a broadly neutralizing human antibody in complex with its target domain in the RABV glycoprotein an
Externí odkaz:
https://doaj.org/article/e6bafc79f9814357b005d33b29f35294
Autor:
Jérémy Dufloo, Ludivine Grzelak, Isabelle Staropoli, Yoann Madec, Laura Tondeur, François Anna, Stéphane Pelleau, Aurélie Wiedemann, Cyril Planchais, Julian Buchrieser, Rémy Robinot, Marie-Noelle Ungeheuer, Hugo Mouquet, Pierre Charneau, Michael White, Yves Lévy, Bruno Hoen, Arnaud Fontanet, Olivier Schwartz, Timothée Bruel
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 5, Pp 100275- (2021)
Summary: Many SARS-CoV-2-infected individuals remain asymptomatic. Little is known about the extent and quality of their antiviral humoral response. Here, we analyze antibody functions in 52 asymptomatic infected individuals, 119 mildly symptomatic,
Externí odkaz:
https://doaj.org/article/e8bb1c9f402e4123ba47b34ff8406c30
Autor:
Walther Haenseler, Stephen N. Sansom, Julian Buchrieser, Sarah E. Newey, Craig S. Moore, Francesca J. Nicholls, Satyan Chintawar, Christian Schnell, Jack P. Antel, Nicholas D. Allen, M. Zameel Cader, Richard Wade-Martins, William S. James, Sally A. Cowley
Publikováno v:
Stem Cell Reports, Vol 8, Iss 6, Pp 1727-1742 (2017)
Microglia are increasingly implicated in brain pathology, particularly neurodegenerative disease, with many genes implicated in Alzheimer's, Parkinson's, and motor neuron disease expressed in microglia. There is, therefore, a need for authentic, effi
Externí odkaz:
https://doaj.org/article/edac014090934a7e8219864d7c951707