Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Julian A. Tanner"'
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 3, Pp 102299- (2024)
Externí odkaz:
https://doaj.org/article/3ac9152dec7f4c4098b88f76b5bc0e47
Autor:
Renata T. Da Costa, Pedro Urquiza, Matheus M. Perez, YunGuang Du, Mei Li Khong, Haiyan Zheng, Mariona Guitart-Mampel, Pia A. Elustondo, Ernest R. Scoma, Vedangi Hambardikar, Beatrix Ueberheide, Julian A. Tanner, Alejandro Cohen, Evgeny V. Pavlov, Cole M. Haynes, Maria E. Solesio
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
The existing literature points towards the presence of robust mitochondrial mechanisms aimed at mitigating protein dyshomeostasis within the organelle. However, the precise molecular composition of these mechanisms remains unclear. Our data show that
Externí odkaz:
https://doaj.org/article/88ee7d20f5ac4d03baa5fa1375c6926b
Autor:
Ryan H. P. Siu, Robert G. Jesky, Yu-Jing Fan, Cyrus C. H. Au-Yeung, Andrew B. Kinghorn, Kwok-Hung Chan, Ivan Fan-Ngai Hung, Julian A. Tanner
Publikováno v:
Biosensors, Vol 14, Iss 10, p 471 (2024)
Gold standard detection of SARS-CoV-2 by reverse transcription quantitative PCR (RT-qPCR) can achieve ultrasensitive viral detection down to a few RNA copies per sample. Yet, the lengthy detection and labor-intensive protocol limit its effectiveness
Externí odkaz:
https://doaj.org/article/17cfb0fb745a4a98a613c251767ee784
Autor:
Mengping Liu, Andrew B. Kinghorn, Lin Wang, Soubhagya K. Bhuyan, Simon Chi-Chin Shiu, Julian A. Tanner
Publikováno v:
Molecules, Vol 29, Iss 6, p 1243 (2024)
Recombinant human bone morphogenetic protein 2 (rhBMP-2) is an FDA-approved growth factor for bone regeneration and repair in medical practice. The therapeutic effects of rhBMP-2 may be enhanced through specific binding to extracellular matrix (ECM)-
Externí odkaz:
https://doaj.org/article/e6cb8a9d33644656a26003ba6e3b799d
Publikováno v:
BMC Medical Education, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background The COVID-19 pandemic and the consequent social distancing measures caused unprecedented disruption for medical and healthcare education. This study examined medical teachers’ experience with emergency remote teaching during the
Externí odkaz:
https://doaj.org/article/68e2bf8ffe9d454fb6879cd4dcf579a0
Autor:
Carsten Schmidt, Anne Kammel, Julian A. Tanner, Andrew B. Kinghorn, Muhammad Moman Khan, Werner Lehmann, Marcus Menger, Uwe Schedler, Peter Schierack, Stefan Rödiger
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract For improving aptamer-ligand binding we have developed a screening system that defines optimal binding buffer composition. Using multiplex assays, one buffer system is needed which guarantees the specific binding of all aptamers. We investig
Externí odkaz:
https://doaj.org/article/88e2442d75234fd1b5a56c6b7976df8d
Autor:
Wei Guo, Andrew B. Kinghorn, Yage Zhang, Qingchuan Li, Aditi Dey Poonam, Julian A. Tanner, Ho Cheung Shum
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Prebiotic compartmentalization could prove essential for the evolution of life. Guo et al. show that liquid-liquid separation in an aqueous two-phase system driven by evaporation may already suffice to facilitate chemical processes required for the R
Externí odkaz:
https://doaj.org/article/04fb803d01e04670a1ef54ca2ad9b2c7
Autor:
Antonio Minopoli, Bartolomeo Della Ventura, Bohdan Lenyk, Francesco Gentile, Julian A. Tanner, Andreas Offenhäusser, Dirk Mayer, Raffaele Velotta
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Reliable plasmonic biosensors with high throughput and ease of use are highly sought after. Here, the authors report a plasmon-enhanced fluorescence antibody-aptamer biosensor based on a gold nanoparticle array, and demonstrate its use for effective
Externí odkaz:
https://doaj.org/article/07531cb4c8cc4d8bb8afabbfbe73a425
Autor:
Shaolin Liang, Andrew B. Kinghorn, Margaritis Voliotis, Julia K. Prague, Johannes D. Veldhuis, Krasimira Tsaneva-Atanasova, Craig A. McArdle, Raymond H. W. Li, Anthony E. G. Cass, Waljit S. Dhillo, Julian A. Tanner
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Assessment of luteinising hormone pulsatility is important in the diagnosis of reproductive disorders. Here the authors develop a DNA aptamer-based electrochemical analysis integrated into a robotic platform for high-throughput and sensitive analysis
Externí odkaz:
https://doaj.org/article/54ce2cef93314854ba9950354efbaf77
Publikováno v:
Cells, Vol 11, Iss 1, p 159 (2022)
A wide variety of nanomaterials have emerged in recent years with advantageous properties for a plethora of therapeutic and diagnostic applications. Such applications include drug delivery, imaging, anti-cancer therapy and radiotherapy. There is a cr
Externí odkaz:
https://doaj.org/article/75622c4c030448df9890bebafd89309f