Zobrazeno 1 - 2
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pro vyhledávání: '"Julian A. Rana"'
Autor:
Jessica S. Williams, Percy P. Tumbale, Mercedes E. Arana, Julian A. Rana, R. Scott Williams, Thomas A. Kunkel
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
DNA ligase 1 (LIG1) finalizes eukaryotic nuclear DNA synthesis by sealing Okazaki fragments using DNA end-joining reactions. Here the authors, by studying an engineered low-fidelity LIG1, reveal that LIG1 is a highly accurate DNA ligase in vivo.
Externí odkaz:
https://doaj.org/article/c7070beaf4664cbf8e117033397ef7e8
Autor:
Percy P. Tumbale, R. Scott Williams, Julian A. Rana, Mercedes E. Arana, Jessica S. Williams, Thomas A. Kunkel
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications
Nature Communications
DNA ligase 1 (LIG1, Cdc9 in yeast) finalizes eukaryotic nuclear DNA replication by sealing Okazaki fragments using DNA end-joining reactions that strongly discriminate against incorrectly paired DNA substrates. Whether intrinsic ligation fidelity con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45919fef4de41c5e110db7eeeb302419
https://doaj.org/article/c7070beaf4664cbf8e117033397ef7e8
https://doaj.org/article/c7070beaf4664cbf8e117033397ef7e8