Zobrazeno 1 - 10
of 225
pro vyhledávání: '"Julian, Adams"'
Autor:
Aviad Pato, Astar Hailu, Dima Yackoubov, Tracey Lodie, Julia Rifman, Yona Geffen, Orit Berhani-Zipori, Avishay Edri, Sherri Cohen, Nurit Brycman, Boaz Buhandler, Moshe Shahor, Nathan Dinowitz, Amram Ben David, Avi Izraeli, Vered Chalifa-Caspi, Liron Levin, Joshua Rabinowitz, Wenyun Lu, Julian Adams
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/8889d445cfab470199a0ade425708109
Autor:
Muhammed H. Rahaman, Frankie Lam, Longjin Zhong, Theodosia Teo, Julian Adams, Mingfeng Yu, Robert W. Milne, Chris Pepper, Noor A. Lokman, Carmela Ricciardelli, Martin K. Oehler, Shudong Wang
Publikováno v:
Molecular Oncology, Vol 13, Iss 10, Pp 2178-2193 (2019)
Colorectal cancer (CRC) remains one of the most lethal human malignancies, and pursuit of new therapeutic targets for treatment has been a major research focus. Cyclin‐dependent kinase 9 (CDK9), which plays a crucial role in transcription, has emer
Externí odkaz:
https://doaj.org/article/cbaa876250d345bd9ed140b6e56eb1f2
Publikováno v:
Cell and Gene Therapy Insights. 8:885-894
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03e96f19861056ec2322d2052bbc395e
https://doi.org/10.18609/cgti.2022.133
https://doi.org/10.18609/cgti.2022.133
Autor:
Watchara Phetluan, Samart Wanchana, Wanchana Aesomnuk, Julian Adams, Mutiara K. Pitaloka, Vinitchan Ruanjaichon, Apichart Vanavichit, Theerayut Toojinda, Julie E. Gray, Siwaret Arikit
Publikováno v:
Plant Science. 330:111624
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce5b463c167bdb67045b772ddd867640
https://doi.org/10.1016/j.plantsci.2023.111624
https://doi.org/10.1016/j.plantsci.2023.111624
Autor:
Liron Levin, Julian Adams, Nurit Brycman, Julia Rifman, Dima Yackoubov, Vered Chalifa-Caspi, Sherri Cohen, Aviad Pato, Joshua D. Rabinowitz, Yona Geffen, Avi Izraeli, Astar Hailu, Tracey Lodie, Nathan Dinowitz, Amram Ben David, Orit Berhani-Zipori, Moshe Shahor, Avishay Edri, Wenyun Lu, Boaz Buhandler
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundNicotinamide (NAM), an allosteric inhibitor of NAD-dependent enzymes, has been shown to preserve cell function and prevent differentiation in ex vivo cell culture. GDA-201 is an investigational natural killer (NK) cell immunotherapy derived
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91f85eab7c02b45927266ee566895662
https://doaj.org/article/8889d445cfab470199a0ade425708109
https://doaj.org/article/8889d445cfab470199a0ade425708109
Autor:
Nathan Dinowitz, Nurit Persi, Aviad Pato, Liron Levin, Orit Berhani-Zipori, Moshe Shahor, Joshua D. Rabinowitz, Frank Cichocki, Julian Adams, Dima Yackoubov, Sherri Cohen, Boaz Buhandler, Amnon Peled, Yona Geffen, Ronit Simantov, Julia Rifman, Amram Ben David, Melanie R. McReynolds, Astar Hailu, Avishai Edri, Vered Caspi, Tracey Lodie, Avi Izraeli, Wenyun Lu
Publikováno v:
Transplantation and Cellular Therapy. 28:S214-S215
Adoptive transfer of NK cells is a promising immunotherapeutic modality, however limited NK cell persistence and proliferation in vivo have historically been barriers to clinical success. Nicotinamide (NAM), an allosteric inhibitor of NAD-dependent e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5590b23fc199f599dbffa03824bdfcf7
https://doi.org/10.1016/s2666-6367(22)00427-4
https://doi.org/10.1016/s2666-6367(22)00427-4
Autor:
Margie Kinnersley, Jared Wenger, Evgueny Kroll, Julian Adams, Gavin Sherlock, Frank Rosenzweig
Publikováno v:
PLoS Genetics, Vol 10, Iss 6, p e1004430 (2014)
A major goal of genetics is to define the relationship between phenotype and genotype, while a major goal of ecology is to identify the rules that govern community assembly. Achieving these goals by analyzing natural systems can be difficult, as sele
Externí odkaz:
https://doaj.org/article/9c522ed2241741ba9cf22eaaf2aa561c
Autor:
Julian Adams, Caroline F. Ribeiro, Alfredo Csibi, Jeremy Tchaicha, Silvano Bosari, Benjamin Larimer, Giorgia Zadra, Scott M. Dehm, Lisa M. Butler, Stefano Cacciatore, Vito J. Palombella, Yeung Ho, Débora Campanella Bastos, Svitlana Tyekucheva, Clyde Bango, Paolo Chetta, Stephen R. Plymate, Stephane Peluso, Massimo Loda, Brian Lawney, Cornelia Photopoulos, Xueliang Gao, Sudeepa Syamala, Ying Huang, Leigh Ellis, Radha L. Kalekar, Umar Mahmood, Laura D’Anello, Takuma Uo, Jeffery L. Kutok, Colm Morrissey, Karen McGovern
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Standard of care for metastatic castration-resistant prostate cancer (mCRPC) mainly relies on suppression of androgen receptor (AR) signaling. This approach has no lasting benefit due to the emergence of resistance mechanisms, such as li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85023da7203a65f84eb88a01c18f73f0
http://europepmc.org/articles/PMC6329966
http://europepmc.org/articles/PMC6329966
CDKI-73: an orally bioavailable and highly efficacious CDK9 inhibitor against acute myeloid leukemia
Autor:
Frankie Lam, Muhammed H. Rahaman, Julian Adams, Jun Peng, Robert W. Milne, Ben Noll, Yingyi Yu, Shudong Wang, Peng Li, Longjin Zhong
Publikováno v:
Investigational New Drugs. 37:625-635
Acute myeloid leukemia (AML) is the most common form of acute leukemia with dismal long-term prognosis with age. The most aggressive subtype of AML is MLL-AML that is characterized by translocations of the mixed-lineage leukemia gene (MLL)and resista
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::778eeef84737669f8e691f08b96247f9
https://doi.org/10.1007/s10637-018-0661-2
https://doi.org/10.1007/s10637-018-0661-2