Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Julia do Amaral, Gomes"'
Autor:
Thayne Woycinck Kowalski, Mariléa Furtado Feira, Vinícius Oliveira Lord, Julia do Amaral Gomes, Giovanna Câmara Giudicelli, Lucas Rosa Fraga, Maria Teresa Vieira Sanseverino, Mariana Recamonde-Mendoza, Lavinia Schuler-Faccini, Fernanda Sales Luiz Vianna
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11515 (2023)
Several molecular mechanisms of thalidomide embryopathy (TE) have been investigated, from anti-angiogenesis to oxidative stress to cereblon binding. Recently, it was discovered that thalidomide and its analogs, named immunomodulatory drugs (IMiDs), i
Externí odkaz:
https://doaj.org/article/882d9e29098243d88589f20bcb00997f
Autor:
Gabriela Elis Wachholz, Julia do Amaral Gomes, Juliano André Boquett, Fernanda Sales Luiz Vianna, Lavínia Schuler-Faccini, Lucas Rosa Fraga
Publikováno v:
Systematic Reviews, Vol 10, Iss 1, Pp 1-7 (2021)
Abstract Background Due to the diversity of studies in animal models reporting that molecular mechanisms are involved in the teratogenic effect of the Zika virus (ZIKV), the objective of the present study is to evaluate the methodological quality of
Externí odkaz:
https://doaj.org/article/ab8c4a6f68ba407495adb47033996406
Autor:
Lavínia Schuler-Faccini, Miguel del Campo, Alfredo García-Alix, Liana O. Ventura, Juliano André Boquett, Vanessa van der Linden, André Pessoa, Hélio van der Linden Júnior, Camila V. Ventura, Mariana Carvalho Leal, Thayne Woycinck Kowalski, Lais Rodrigues Gerzson, Carla Skilhan de Almeida, Lucélia Santi, Walter O. Beys-da-Silva, André Quincozes-Santos, Jorge A. Guimarães, Patricia P. Garcez, Julia do Amaral Gomes, Fernanda Sales Luiz Vianna, André Anjos da Silva, Lucas Rosa Fraga, Maria Teresa Vieira Sanseverino, Alysson R. Muotri, Rafael Lopes da Rosa, Alberto Mantovani Abeche, Clairton Marcolongo-Pereira, Diogo O. Souza
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Five years after the identification of Zika virus as a human teratogen, we reviewed the early clinical manifestations, collectively called congenital Zika syndrome (CZS). Children with CZS have a very poor prognosis with extremely low performance in
Externí odkaz:
https://doaj.org/article/faaf7db36c3d4f5db68c0f9e5cc7f044
Autor:
Augusto César Cardoso-dos-Santos, Ruanna Sandrelly de Miranda Alves, Ana Cláudia Medeiros-de-Souza, João Matheus Bremm, Julia do Amaral Gomes, Ronaldo Fernandes Santos Alves, Valdelaine Etelvina Miranda de Araujo, Giovanny Vinícius Araújo de França
Publikováno v:
Epidemiologia e Serviços de Saúde, Vol 30, Iss 4 (2021)
Resumo Objetivo: Identificar registros de anomalias congênitas com cobertura nacional existentes no mundo, destacando suas principais características históricas e operacionais. Métodos: Revisão documental, mediante busca na base Medline/Pubmed e
Externí odkaz:
https://doaj.org/article/40d81b6739c84aa3a61fa0f0123ca8cb
Autor:
Thayne Woycinck Kowalski, Gabriela Barreto Caldas-Garcia, Julia do Amaral Gomes, Lucas Rosa Fraga, Lavínia Schuler-Faccini, Mariana Recamonde-Mendoza, Vanessa Rodrigues Paixão-Côrtes, Fernanda Sales Luiz Vianna
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
The identification of thalidomide–Cereblon-induced SALL4 degradation has brought new understanding for thalidomide embryopathy (TE) differences across species. Some questions, however, regarding species variability, still remain. The aim of this st
Externí odkaz:
https://doaj.org/article/5e3629fedaf641da9c5481c62de35876
Autor:
Julia do Amaral Gomes, Thayne Woycinck Kowalski, Lucas Rosa Fraga, Gabriel S. Macedo, Maria Teresa Vieira Sanseverino, Lavínia Schuler-Faccini, Fernanda Sales Luiz Vianna
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Abstract Thalidomide is widely used for several diseases; however, it causes malformations in embryos exposed during pregnancy. The complete understanding of the mechanisms by which thalidomide affects the embryo development has not yet been obtained
Externí odkaz:
https://doaj.org/article/47bc5eea5a014c35bbd8994693675834
Autor:
Julia do Amaral Gomes, Emilie Willoch Olstad, Thayne Woycinck Kowalski, Kristina Gervin, Fernanda Sales Luiz Vianna, Lavínia Schüler-Faccini, Hedvig Marie Egeland Nordeng
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Since the 1960s, drugs have been known to cause teratogenic effects in humans. Such teratogenicity has been postulated to be influenced by genetics. The aim of this review was to provide an overview of the current knowledge on genetic susceptibility
Externí odkaz:
https://doaj.org/article/c0fc9d1af5d142219b551c84244fe4cd
Autor:
Thayne Woycinck Kowalski, Julia do Amaral Gomes, Mariléa Furtado Feira, Ágata de Vargas Dupont, Mariana Recamonde-Mendoza, Fernanda Sales Luiz Vianna
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Embryofetal development is a critical process that needs a strict epigenetic control, however, perturbations in this balance might lead to the occurrence of congenital anomalies. It is known that anticonvulsants potentially affect epigenetics-related
Externí odkaz:
https://doaj.org/article/b7ad8f5357a44deea5421a09ac9bb7f5
Autor:
Bruna Duarte Rengel, Thayne Woycinck Kowalski, João Matheus Bremm, Julia do Amaral Gomes, Lavínia Schüler‐Faccini, Fernanda Sales Luiz Vianna, Lucas Rosa Fraga
Publikováno v:
Birth defects researchREFERENCES. 114(20)
HAND2 is a transcription factor important for embryonic development, required for limbs and cardiovascular development. Thalidomide is a drug responsible to a spectrum of congenital anomalies known as Thalidomide Embryopathy (TE), which includes main
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d85cebb057185ef3df0f017c97290b1
https://pubmed.ncbi.nlm.nih.gov/36177858
https://pubmed.ncbi.nlm.nih.gov/36177858
Autor:
Julia do Amaral Gomes, João Matheus Bremm, Augusto César Cardoso-dos-Santos, Valdelaine Etelvina Miranda de Araújo, Giovanny Vinícius Araújo de França, Ruanna Sandrelly de Miranda Alves, Ronaldo Fernandes Santos Alves, Ana Cláudia Medeiros-de-Souza
Publikováno v:
Epidemiologia e Serviços de Saúde, Vol 30, Iss 4 (2021)
Resumo Objetivo: Identificar registros de anomalias congênitas com cobertura nacional existentes no mundo, destacando suas principais características históricas e operacionais. Métodos: Revisão documental, mediante busca na base Medline/Pubmed e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e93a2875c56bc86bb5d3511d4d4fc70
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2237-96222021000400702&tlng=en
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2237-96222021000400702&tlng=en