Zobrazeno 1 - 10 of 31 pro vyhledávání: '"Julia and Xu"'
1
Akademický článek
Fatty acid nitroalkenes – Multi-target agents for the treatment of sickle cell disease
Autor: Fabliha A. Chowdhury, Nicole Colussi, Malini Sharma, Katherine C. Wood, Julia Z. Xu, Bruce A. Freeman, Francisco J. Schopfer, Adam C. Straub
Publikováno v: Redox Biology, Vol 68, Iss , Pp 102941- (2023)
Sickle cell disease (SCD) is a hereditary hematological disease with high morbidity and mortality rates worldwide. Despite being monogenic, SCD patients display a plethora of disease-associated complications including anemia, oxidative stress, steril
Externí odkaz: https://doaj.org/article/e1bc2e80353f4d6091066d02a5726433
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2
Akademický článek
Release of hepatic xanthine oxidase (XO) to the circulation is protective in intravascular hemolytic crisis
Autor: Heidi M. Schmidt, Evan R. DeVallance, Sara E. Lewis, Katherine C. Wood, Gowtham K. Annarapu, Mara Carreño, Scott A. Hahn, Madison Seman, Brooke A. Maxwell, Emily A. Hileman, Julia Z. Xu, Murugesan Velayutham, Werner J. Geldenhuys, Dario A. Vitturi, Sruti Shiva, Eric E. Kelley, Adam C. Straub
Publikováno v: Redox Biology, Vol 62, Iss , Pp 102636- (2023)
Xanthine oxidase (XO) catalyzes the catabolism of hypoxanthine to xanthine and xanthine to uric acid, generating oxidants as a byproduct. Importantly, XO activity is elevated in numerous hemolytic conditions including sickle cell disease (SCD); howev
Externí odkaz: https://doaj.org/article/fc1d13f5ed7a4f76bf1f12017427f9c4
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3
Akademický článek
Identification of optimal thalassemia screening strategies for migrant populations in Thailand using a qualitative approach
Autor: Julia Z. Xu, Meghan Foe, Wilaslak Tanongsaksakul, Thidarat Suksangpleng, Supachai Ekwattanakit, Suchada Riolueang, Marilyn J. Telen, Bonnie N. Kaiser, Vip Viprakasit
Publikováno v: BMC Public Health, Vol 21, Iss 1, Pp 1-13 (2021)
Abstract Background Thalassemia is a common inherited hemoglobin disorder in Southeast Asia. Severe thalassemia can lead to significant morbidity for patients and economic strain for under-resourced health systems. Thailand’s thalassemia prevention
Externí odkaz: https://doaj.org/article/7dd87dc605924fb29972b6720a46689b
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4
Akademický článek
Feasibility of and barriers to thalassemia screening in migrant populations: a cross-sectional study of Myanmar and Cambodian migrants in Thailand
Autor: Julia Z. Xu, Wilaslak Tanongsaksakul, Thidarat Suksangpleng, Supachai Ekwattanakit, Suchada Riolueang, Marilyn J. Telen, Vip Viprakasit
Publikováno v: BMC Public Health, Vol 21, Iss 1, Pp 1-15 (2021)
Abstract Background Thalassemia, an inherited hemoglobin disorder, has become a global public health problem due to population migration. Evidence-based strategies for thalassemia prevention in migrants are lacking. We characterized barriers to thala
Externí odkaz: https://doaj.org/article/7d218a91efb24f56920c93d1580d516d
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5
Akademický článek
The carrier state for sickle cell disease is not completely harmless
Autor: Julia Zhe Xu, Swee Lay Thein
Publikováno v: Haematologica, Vol 104, Iss 6 (2019)
Externí odkaz: https://doaj.org/article/9c3c20e622104681bdc117b83a2693de
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10
Revisiting anemia in sickle cell disease and finding the balance with therapeutic approaches
Autor: Julia Zhe Xu, Swee Lay Thein
Publikováno v: Blood
Chronic hemolytic anemia and intermittent acute pain episodes are the 2 hallmark characteristics of sickle cell disease (SCD). Anemia in SCD not only signals a reduction of red cell mass and oxygen delivery, but also ongoing red cell breakdown and re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::162747cbacbdff15da83974dfa5b1143
https://europepmc.org/articles/PMC9121844/
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