Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Julia Zerle"'
Autor:
Florian Giesert, Andreas Hofmann, Alexander Bürger, Julia Zerle, Karina Kloos, Ulrich Hafen, Luise Ernst, Jingzhong Zhang, Daniela Maria Vogt-Weisenhorn, Wolfgang Wurst
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63778 (2013)
Missense mutations in the leucine-rich repeat kinase 2 gene (LRRK2) are linked to autosomal dominant forms of Parkinson's disease (PD). In order to get insights into the physiological role of Lrrk2, we examined the distribution of Lrrk2 mRNA and diff
Externí odkaz:
https://doaj.org/article/f515b655e7854486bdadf266ac6eac2a
Autor:
Michael J. Devine, Alice Kaganovich, Mina Ryten, Adamantios Mamais, Daniah Trabzuni, Claudia Manzoni, Philip McGoldrick, Diane Chan, Allissa Dillman, Julia Zerle, Susannah Horan, Jan-Willem Taanman, John Hardy, Jose-Felix Marti-Masso, Daniel Healy, Anthony H. Schapira, Benjamin Wolozin, Rina Bandopadhyay, Mark R. Cookson, Marcel P. van der Brug, Patrick A. Lewis
Publikováno v:
PLoS ONE, Vol 7, Iss 1 (2012)
Externí odkaz:
https://doaj.org/article/46de591ce9b249fda4d5222348b06db5
Pathogenic LRRK2 mutations do not alter gene expression in cell model systems or human brain tissue.
Autor:
Michael J Devine, Alice Kaganovich, Mina Ryten, Adamantios Mamais, Daniah Trabzuni, Claudia Manzoni, Philip McGoldrick, Diane Chan, Allissa Dillman, Julia Zerle, Susannah Horan, Jan-Willem Taanman, John Hardy, Jose-Felix Marti-Masso, Daniel Healy, Anthony H Schapira, Benjamin Wolozin, Rina Bandopadhyay, Mark R Cookson, Marcel P van der Brug, Patrick A Lewis
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22489 (2011)
Point mutations in LRRK2 cause autosomal dominant Parkinson's disease. Despite extensive efforts to determine the mechanism of cell death in patients with LRRK2 mutations, the aetiology of LRRK2 PD is not well understood. To examine possible alterati
Externí odkaz:
https://doaj.org/article/c6fe6ed743ea4ec3bf74262e0c03b0ea
Autor:
Luise Ernst, D. M. Vogt Weisenhorn, Lisa Glasl, Annemarie Zimprich, Florian Giesert, G. Piccoli, Sabine M. Hölter, Julia Zerle, Wolfgang Wurst, C. Stautner
Publikováno v:
Neurobiology of Disease, Vol 105, Iss, Pp 179-193 (2017)
Neurobiology of disease 105, 179-193 (2017). doi:10.1016/j.nbd.2017.05.013
Neurobiology of disease 105, 179-193 (2017). doi:10.1016/j.nbd.2017.05.013
The aim of the present study was to further explore the in vivo function of the Leucine-rich repeat kinase 2 (LRRK2)-gene, which is mutated in certain familial forms of Parkinson's disease (PD). We generated a mouse model harboring the disease-associ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5d68f95eb6c4cce08851f130b9bb243
http://www.sciencedirect.com/science/article/pii/S0969996117301237
http://www.sciencedirect.com/science/article/pii/S0969996117301237
Autor:
Ralf Kühn, Ulrich Hafen, Martin Hrabé de Angelis, Andreas Hofmann, Karina Kloos, Daniela M. Vogt Weisenhorn, Julia Zerle, Lisa Glasl, Sabine M. Hölter, Konstanze F. Winklhofer, Florian Giesert, Anne Roethig, Jingzhong Zhang, Wolfgang Wurst, Barbara Di Benedetto
Publikováno v:
Experimental neurology 235(1), 214-227 (2012). doi:10.1016/j.expneurol.2012.01.002
Parkinson's Disease (PD) is the most common neurodegenerative movement disorder. Autosomal-recessive mutations in the mitochondrial protein kinase PINK1 (PTEN-induced kinase 1) account for 1-2% of the hereditary early-onset cases. To study the mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98f86d1881576dcab83bb1a0a9e5d001
https://pubmed.ncbi.nlm.nih.gov/22265660
https://pubmed.ncbi.nlm.nih.gov/22265660