Soluble Epoxide Hydrolase Derived Linoleic Acid Oxylipins, Small Vessel Disease Markers, and Neurodegeneration in Stroke

Autor: Di Yu, Nuanyi Liang, Julia Zebarth, Qing Shen, Miracle Ozzoude, Maged Goubran, Jennifer S. Rabin, Joel Ramirez, Christopher J. M. Scott, Fuqiang Gao, Robert Bartha, Sean Symons, Seyyed Mohammad Hassan Haddad, Courtney Berezuk, Brian Tan, Donna Kwan, Robert A. Hegele, Allison A. Dilliott, Nuwan D. Nanayakkara, Malcolm A. Binns, Derek Beaton, Stephen R. Arnott, Jane M. Lawrence‐Dewar, Ayman Hassan, Dar Dowlatshahi, Jennifer Mandzia, Demetrios Sahlas, Leanne Casaubon, Gustavo Saposnik, Yurika Otoki, Krista L. Lanctôt, Mario Masellis, Sandra E. Black, Richard H. Swartz, Ameer Y. Taha, Walter Swardfager, Natalie Rashkovan, Agessandro Abrahao, Lorne Zinman, Alisia Bonnick, Christopher Scott, Melissa Holmes, Sabrina Adamo, Morris Freedman, Mojdeh Zamyadi, Stephen Arnott, Malcolm Binns, Pradeep Raamana, Stephen Strother, Kelly Sunderland, Athena Theyers, Abiramy Uthirakumaran, Brian Levine, Angela Troyer, Michael Strong, Peter Kleinstiver, Michael Borrie, Elizabeth Finger, Christen Shoesmith, Frederico Faria, Manuel Montero‐Odasso, Yanina Sarquis‐Adamson, Alanna Black, Allison Ann Dilliott, Rob Hegele, John Robinson, Sali Farhan, Rob Bartha, Hassan Haddad, Nuwan Nanayakkara, Guangyong Zou, Stephen Pasternak, JB Orange, Angela Roberts, Mandar Jog, Dallas Seitz, Don Brien, Ying Chen, Brian Coe, Doug Munoz, Paula McLaughlin, Alicia Peltsch, Susan Bronskill, Wendy Lou, Sanjeev Kumar, Bruce Pollock, Tarek Rajji, David Tang‐Wai, Carmela Tartaglia, Brenda Varriano, Marvin Chum, John Turnbull, Jane Lawrence‐Dewar, Julia Fraser, Bill McIlroy, Ben Cornish, Karen Van Ooteghem, Chris Hudson, Elena Leontieva, Wendy Hatch, Faryan Tayyari, Sherif Defrawy, Edward Margolin, Efrem Mandelcorn, Barry Greenberg, Anthony Lang, Connie Marras, Andrew Frank, David Grimes, Dennis Bulman, John Woulfe, Mahdi Ghani, Tom Steeves, David Munoz, Corinne Fischer, Ekaterina Rogaeva, Sujeevini Sujanthan, David Breen, Roger A. Dixon

Publikováno v: Journal of the American Heart Association, vol 12, iss 1

Background Cerebral small vessel disease is associated with higher ratios of soluble‐epoxide hydrolase derived linoleic acid diols (12,13‐dihydroxyoctadecenoic acid [DiHOME] and 9,10‐DiHOME) to their parent epoxides (12(13)‐epoxyoctadecenoic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a01e12bcd2e05b91fd68b5815a18588
https://pubmed.ncbi.nlm.nih.gov/36583428

P93. Inflammatory Markers in Type 2 Diabetes and Cognitive Impairment: A Systematic Review and Meta-Analysis

Autor: Natasha Z. Anita, Julia Zebarth, Brian Chan, Che-Yuan Wu, Taha Syed, Dinie Shahrul, Michelle M. Nguyen, Maureen Pakosh, Nathan Herrmann, Krista L. Lanctôt, Walter Swardfager

Publikováno v: Biological Psychiatry. 91:S124-S125

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7f3c007ce49d2a90aeb148007bf33f24
https://doi.org/10.1016/j.biopsych.2022.02.327

Prolonged Low-Dose Dioxin Exposure Impairs Metabolic Adaptability to High-Fat Diet Feeding in Female but Not Male Mice

Autor: Rémi Gagné, Julie K. Buick, Andrew Williams, Myriam P Hoyeck, Kayleigh R C Rick, Carole L. Yauk, Geronimo Matteo, Jennifer E. Bruin, Hannah L Blair, Julia Zebarth

Publikováno v: Endocrinology

Context Human studies consistently show an association between exposure to persistent organic pollutants, including 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD, aka “dioxin”), and increased diabetes risk. We previously showed that a single high-dos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbde7c1a717d3ba6b5eeaaa5b10affd6
https://doi.org/10.1210/endocr/bqab050

Prolonged low-dose dioxin exposure impairs metabolic adaptability to high-fat diet feeding in female but not male mice

Autor: Rémi Gagné, Julie K. Buick, Hannah L Blair, Andrew Williams, Kayleigh R C Rick, Geronimo Matteo, Carole L. Yauk, Julia Zebarth, Jennifer E. Bruin, Myriam P Hoyeck

ObjectiveHuman studies consistently show an association between exposure to persistent organic pollutants, including 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD, aka “dioxin”), and increased diabetes risk, but rarely consider potential sex differen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0151dbaf14a966710294068652872b48
https://doi.org/10.1101/2020.09.12.294587