Role of fibrillin-2 in the control of TGF-β activation in tumor angiogenesis and connective tissue disorders

Autor: Arjan W. Griffioen, Elisabeth J. M. Huijbers, Karlijn van Loon, Julia Yemelyanenko-Lyalenko, Coert Margadant

Publikováno v: van Loon, K, Yemelyanenko-Lyalenko, J, Margadant, C, Griffioen, A W & Huijbers, E J M 2020, ' Role of fibrillin-2 in the control of TGF-β activation in tumor angiogenesis and connective tissue disorders ', Biochimica et Biophysica Acta-Reviews on Cancer, vol. 1873, no. 2, 188354 . https://doi.org/10.1016/j.bbcan.2020.188354

Fibrillins constitute a family of large extracellular glycoproteins which multimerize to form microfibrils, an important structure in the extracellular matrix. It has long been assumed that fibrillin-2 was barely present during postnatal life, but it

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