Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Julia Wenz"'
Autor:
Sorin Armeanu-Ebinger, Julia Wenz, Guido Seitz, Ivo Leuschner, Rupert Handgretinger, Ulrike A Mau-Holzmann, Michael Bonin, Bence Sipos, Jörg Fuchs, Steven W Warmann
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e38223 (2012)
Current treatment of paediatric hepatocellular carcinoma (HCC) is often inefficient due to advanced disease at diagnosis and resistance to common drugs. The aim of this study was to generate a cell line derived from a paediatric HCC in order to expan
Externí odkaz:
https://doaj.org/article/ad2e010ed1d748ef807466abed93dadf
Autor:
Verena Ellerkamp, Sorin Armeanu-Ebinger, Julia Wenz, Steven W Warmann, Juergen Schäfer, Peter Ruck, Joerg Fuchs
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23419 (2011)
Investigation of hepatoblastoma in experimental conditions contributes relevantly to a detailed understanding of tumor biology and the investigation of new treatment approaches. Most systematical analyses currently use subcutaneous xenografts. We est
Externí odkaz:
https://doaj.org/article/4dda64c1de704a7db7d5c42049f53c4a
Autor:
Alexander Dewerth, Carmen Eicher, Justus Lieber, Bettina Kirchner, Sorin Armeanu-Ebinger, Julia Wenz, Steven W. Warmann, Joerg Fuchs
Publikováno v:
Oncology Reports. 29:646-652
The response of standard-risk hepatoblastoma (HB) to neoadjuvant cisplatin (CDDP) chemotherapy is excellent; however, in high-risk HB, drug resistance remains a major challenge. Alternative therapeutic strategies may consider combining cytotoxic drug
Autor:
Alexander Hoh, Joerg Fuchs, Sorin Armeanu-Ebinger, Alexander Dewerth, Fabian Vogt, Patrick A. Baeuerle, Steven W. Warmann, Julia Wenz
Publikováno v:
Liver International. 33:127-136
Background Chemoresistance and advanced tumour stage at time of diagnosis are the major reasons for poor treatment results in hepatoblastoma (HB) and paediatric hepatocellular carcinoma (HCC). Positive results with transplantation of liver and bone m
Autor:
Annika Dimitrov-Discher, Julia Wenzel, Nadja Kabisch, Jan Hemmerling, Maxie Bunz, Jonas Schöndorf, Henrik Walter, Ilya M. Veer, Mazda Adli
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract We examined the influence of three major environmental variables at the place of residence as potential moderating variables for neurofunctional activation during a social-stress paradigm. Data from functional magnetic resonance imaging of 4
Externí odkaz:
https://doaj.org/article/59a98db6d3bb4ad2b539eb2fc092c0bb
Autor:
Julia Wenz, Jörg Fuchs, Sorin Armeanu-Ebinger, Justus Lieber, Verena Ellerkamp, Fabian Vogt, Steven W. Warmann
Publikováno v:
Experimental cell research. 322(1)
Drug resistance and metastasis remain major challenges in the treatment of high-risk hepatoblastoma (HB) and require the development of alternative therapeutic strategies. Modulation of apoptosis in HB cells enhances the sensitivity of these cells to
Publikováno v:
Oncoimmunology
Hepatoblastoma (HB) is the most common liver cancer in children. Recurrence of HB after chemotherapy and surgery is frequent among high-risk patients and is associated with chemoresistance. Immunotherapy may improve poor treatment outcomes in HB pati
Autor:
Joerg Fuchs, Steven W. Warmann, Verena Ellerkamp, Sorin Armeanu-Ebinger, Justus Lieber, Julia Wenz, C. Nagel
Publikováno v:
Pediatric surgery international. 29(2)
The proto-oncogene beta-catenin is linked to an abnormal activation of the Wnt/beta-catenin-pathway and shows mutations in 50–90 % of hepatoblastoma (HB). Corresponding, the recently published murine orthotopic HB model differs from the former subc
Publikováno v:
Frontiers in bioscience (Elite edition). 4(6)
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is responsible for cell death in many cancer cells while being non-toxic for most normal cells. In this study, we investigated the role of TRAIL in human hepatoblastoma (HB) cells and an
Autor:
Bettina Kirchner, Justus Lieber, Sorin Armeanu-Ebinger, Joerg Fuchs, Steven W. Warmann, Verena Ellerkamp, Julia Wenz
Publikováno v:
Pediatric surgery international. 28(2)
Drug resistance remains a major challenge for the treatment of high-risk hepatoblastoma (HB). To enhance effectiveness of chemotherapy we modulate apoptosis in HB cells in vitro.Viability was monitored in HB cells (HuH6, HepT1) and fibroblasts in mon