Výsledky vyhledávání - "Julia Waizenegger"

Akademický článek

Pyrrolizidine Alkaloids Disturb Bile Acid Homeostasis in the Human Hepatoma Cell Line HepaRG

Autor: Julia Waizenegger, Josephin Glück, Marcus Henricsson, Claudia Luckert, Albert Braeuning, Stefanie Hessel-Pras

Publikováno v: Foods, Vol 10, Iss 1, p 161 (2021)

1,2-unsaturated pyrrolizidine alkaloids (PAs) belong to a group of secondary plant metabolites. Exposure to PA-contaminated feed and food may cause severe hepatotoxicity. A pathway possibly involved in PA toxicity is the disturbance of bile acid home

Externí odkaz: https://doaj.org/article/3ac1c816631e430594d268fa914ffef1

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Transcriptomics analysis of hepatotoxicity induced by the pesticides imazalil, thiacloprid and clothianidin alone or in binary mixtures in a 28-day study in female Wistar rats

Autor: Jimmy Alarcan, Albert Braeuning, Claudia Luckert, Alfonso Lampen, Philip Marx-Stoelting, Heike Sprenger, Dajana Lichtenstein, Julia Waizenegger

Publikováno v: Archives of Toxicology

Co-occurrence of pesticide residues in food commodities raises a potential safety issue as their mixture effects on human health are largely unknown. In a previous study, we reported the toxicological effects (pathology and histopathology) of imazali

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3e0504d2419bd1c295b874359dbd12a
http://europepmc.org/articles/PMC7904562

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Pyrrolizidine Alkaloids Disturb Bile Acid Homeostasis in the Human Hepatoma Cell Line HepaRG

Autor: Claudia Luckert, Albert Braeuning, Josephin Glück, Julia Waizenegger, Stefanie Hessel-Pras, Marcus Henricsson

Publikováno v: Foods
Volume 10
Issue 1
Foods, Vol 10, Iss 161, p 161 (2021)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::151bb200af22d1766f9d598261dc8e97

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Role of Vitamin D in Preventing and Treating Selected Extraskeletal Diseases—An Umbrella Review

Autor: Stefan Pilz, Jakob Linseisen, Dorothee Volkert, Jana B. Ernst, Friederike Maretzke, Angela Bechthold, Gabriele I. Stangl, Julia Waizenegger, Jörg Reichrath, Armin Zittermann, Michael Wagner, Sarah Egert, Debora Melo van Lent, Peter Stehle

Publikováno v: Nutrients
Nutrients, Vol 12, Iss 969, p 969 (2020)

Evidence is accumulating that vitamin D may have beneficial effects on respiratory tract, autoimmune, neuro-degenerative, and mental diseases. The present umbrella review of systematic reviews (SRs) of cohort studies and randomised controlled trials

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1605dc2d1a45939391b726890ee7f8b5
https://opus4.kobv.de/opus4-fau/files/13624/nutrients-12-00969-v2.pdf

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Hepatotoxicity of the pesticides imazalil, thiacloprid and clothianidin – Individual and mixture effects in a 28-day study in female Wistar rats

Autor: Marize de Lourdes Marzo Solano, Raju Prasad Sharma, Claudia Luckert, Philip Marx-Stoelting, Dajana Lichtenstein, Ad A. C. M. Peijnenburg, Jimmy Alarcan, Albert Braeuning, Geert Stoopen, Alfonso Lampen, Julia Waizenegger, Vikas Kumar

Publikováno v: Food and Chemical Toxicology 140 (2020)
Food and Chemical Toxicology, 140

Humans are exposed to pesticide residues through various food products. As these residues can occur in mixtures, there is a need to investigate possible mixture effects on human health. Recent exposure studies revealed the preponderance of imazalil,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d50e9e6b69d290e6b8bd8d8f2fb0076f
https://doi.org/10.1016/j.fct.2020.111306

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Structure-dependent induction of apoptosis by hepatotoxic pyrrolizidine alkaloids in the human hepatoma cell line HepaRG: Single versus repeated exposure

Autor: Stefanie Hessel-Pras, Alfonso Lampen, Albert Braeuning, Markus F. Templin, Julia Waizenegger

Publikováno v: Food and Chemical Toxicology. 114:215-226

Pyrrolizidine alkaloids (PA) are secondary plant compounds. PA intoxication in humans causes severe acute and chronic hepatotoxicity. However, the molecular mechanisms of PA hepatotoxicity in humans are not well understood yet. Therefore, we investig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0545457dc1a898798a5587963f956904
https://doi.org/10.1016/j.fct.2018.02.036

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Pyrrolizidine Alkaloids Induce Cell Death in Human HepaRG Cells in a Structure-Dependent Manner

Autor: Julia Waizenegger, Albert Braeuning, Josephin Glück, Stefanie Hessel-Pras

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 202, p 202 (2021)
Volume 22
Issue 1

Pyrrolizidine alkaloids (PAs) are a group of secondary metabolites produced in various plant species as a defense mechanism against herbivores. PAs consist of a necine base, which is esterified with one or two necine acids. Humans are exposed to PAs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e41551d3139a0a92da0c122a4d7fbbd6
https://doi.org/10.3390/ijms22010202

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Caffeine Exposure in Children and Adolescents Consuming Ready-to-Drink Coffee Products

Autor: Silvio Castriglia, Ute Alexy, Dirk W. Lachenmeier, Julia Waizenegger, Mathilde Kersting, Rüdiger Schneider, Winfried Ruge, Gertrud Winkler

Publikováno v: Journal of Caffeine Research. 1:200-205

Background: Caffeine may cause adverse effects in children, and Health Canada recommends a maximum daily caffeine intake of 2.5 mg per kilogram of body weight (mg/kg bw) for children under 12 years. Although coffee beverages, especially ready-to-drin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::626a48babca3dd8f11d4d053b8936ff3
https://doi.org/10.1089/jcr.2011.0024

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