Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Julia Vipond"'
Autor:
M. Gill Hartley, Isobel H. Norville, Mark I. Richards, Kay B. Barnes, Kevin R. Bewley, Julia Vipond, Emma Rayner, Andreas Vente, Stuart J. Armstrong, Sarah V. Harding
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Finafloxacin is a novel fluoroquinolone with optimal antibacterial activity in low pH environments, therefore offering a therapeutic advantage over some traditional antibiotics, in treating bacterial infections associated with acidic foci. Coxiella b
Externí odkaz:
https://doaj.org/article/f4f2e56b2dbc445d90035502bac07138
Autor:
Stuart D. Dowall, Kevin Bewley, Robert J. Watson, Seshadri S. Vasan, Chandradhish Ghosh, Mohini M. Konai, Gro Gausdal, James B. Lorens, Jason Long, Wendy Barclay, Isabel Garcia-Dorival, Julian Hiscox, Andrew Bosworth, Irene Taylor, Linda Easterbrook, James Pitman, Sian Summers, Jenny Chan-Pensley, Simon Funnell, Julia Vipond, Sue Charlton, Jayanta Haldar, Roger Hewson, Miles W. Carroll
Publikováno v:
Viruses, Vol 8, Iss 11, p 277 (2016)
In light of the recent outbreak of Ebola virus (EBOV) disease in West Africa, there have been renewed efforts to search for effective antiviral countermeasures. A range of compounds currently available with broad antimicrobial activity have been test
Externí odkaz:
https://doaj.org/article/7dc2cb79f6f64d30b56a604b5dc35a8e
Autor:
E. Rayner, K. A. Clay, Julia Vipond, K. Godwin, Stuart J. Armstrong, M. G. Hartley, Isobel H. Norville, Timothy P. Atkins, Martha J. Bailey, Kevin R. Bewley
Publikováno v:
Antimicrobial Agents and Chemotherapy
Q fever, caused by the intracellular pathogen Coxiella burnetii, is traditionally treated using tetracycline antibiotics, such as doxycycline. Doxycycline is often poorly tolerated, and antibiotic-resistant strains have been isolated. In this study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54dde7072b00f934d476eaf233e09f39
http://europepmc.org/articles/PMC8522727
http://europepmc.org/articles/PMC8522727
Autor:
Julia A. Tree, Simon R. Bate, Julia Vipond, Graham Hall, Allen D. G. Roberts, Geoffrey Pearson, Emma Rayner, Simon G. P. Funnell, Graham J. Hatch
Publikováno v:
Journal of Applied Microbiology
Aims The goal of this study was to examine, for the first time, the virulence and pathogenicity of aerosolized Burkholderia pseudomallei, strain NCTC 13392, in BALB/c mice in order to develop an animal model for testing novel medical countermeasures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b6fb9b8578deab65652470e60070161
https://doi.org/10.1111/jam.14396
https://doi.org/10.1111/jam.14396
Publikováno v:
Antimicrobial Agents and Chemotherapy. 59:7687-7692
Left untreated, inhalation anthrax is usually fatal. Vegetative forms of Bacillus anthracis survive in blood and tissues during infection due to elaboration of a protective poly-γ- d -glutamic acid (PDGA) capsule that permits uncontrolled bacterial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90dd5cd1c1380a154ba5d0bfc2630953
https://doi.org/10.1128/aac.01547-15
https://doi.org/10.1128/aac.01547-15
Autor:
James D. Blanchard, Julia Vipond, Karleigh A. Hamblin, James Pitman, Stuart J. Armstrong, D. J. Atkinson, Graham Hall, Isobel H. Norville, Graham J. Hatch, Timothy P. Atkins, Emma Rayner, Kevin R. Bewley
Publikováno v:
Antimicrobial Agents and Chemotherapy. 58:5510-5518
Encapsulation of antibiotics may improve treatment of intracellular infections by prolonging antibiotic release and improving antibiotic uptake into cells. In this study, liposome-encapsulated ciprofloxacin for inhalation (CFI) was evaluated as a pos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09ab2f92e42b2f2da6d29b236cd44e90
https://doi.org/10.1128/aac.03443-14
https://doi.org/10.1128/aac.03443-14
Autor:
Emma Rayner, Victoria A. Graham, Geoff Pearson, Julia Vipond, Graham Hall, Simon G. P. Funnell, Julia A. Tree, Kimberley Steeds, Irene Taylor, Allen D. G. Roberts, Kevin R. Bewley, Graham J. Hatch, Mike Dennis
To evaluate new vaccines when human efficacy studies are not possible, the FDA's “Animal Rule” requires well-characterized models of infection. Thus, in the present study, the early pathogenic events of monkeypox infection in nonhuman primates, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92ecd2f37c53d377dd9e30dfa0d6553f
https://europepmc.org/articles/PMC4442344/
https://europepmc.org/articles/PMC4442344/
Autor:
Nigel P. Minton, Ann Williams, Simon O. Clark, Helen Shuttleworth, Graham J. Hatch, Emma Allen-Vercoe, Philip Marsh, Karen Blake, Joanna Bacon, Toby Hampshire, Julia Vipond, Richard Vipond, Karen E. Gooch
Publikováno v:
Vaccine. 24:6340-6350
Putative TB vaccine candidates were selected from lists of genes induced in response to in vivo-like stimuli, such as low oxygen and carbon starvation or growth in macrophages, and tested as plasmid DNA vaccines for their ability to protect against M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd2f444df30343a1281e9d0fbef0b6b1
https://doi.org/10.1016/j.vaccine.2006.05.025
https://doi.org/10.1016/j.vaccine.2006.05.025
Autor:
Julia Vipond, Richard Vipond, Julia A. Tree, Philip Marsh, Else Marie Agger, Ann Williams, Simon O. Clark, Graham J. Hatch
Publikováno v:
Tuberculosis. 86:218-224
Summary A selection of previously identified protective Mycobacterium tuberculosis DNA vaccines were re-formulated as proteins and administered with a Th1-inducing adjuvant to help stimulate the relevant immune responses necessary for protection. All
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5ce0d0390a8e6cf29574b871d96ce9c
https://doi.org/10.1016/j.tube.2006.01.014
https://doi.org/10.1016/j.tube.2006.01.014
Autor:
Simon G. P. Funnell, Julia Vipond, Simon R. Bate, Graham J. Hatch, Nicola Jones, Anthony Crook
Publikováno v:
Journal of Infectious Diseases and Therapy.
Anthrax is a potentially fatal disease in man, and events of the last decade have highlighted the possibility for Bacillus anthracis to be used as a biological weapon through deliberate release. Whilst outbreaks of anthrax occur in several countries,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f86a22db495ef24c8eac0f808c7faa0
https://doi.org/10.4172/2332-0877.1000175
https://doi.org/10.4172/2332-0877.1000175