Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Julia V. Busik"'
Autor:
Nicole El-Darzi, Natalia Mast, Sandra S. Hammer, Tim F. Dorweiler, Julia V. Busik, Irina A. Pikuleva
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 2, Pp 100323- (2023)
CYP46A1 is a CNS-specific enzyme, which eliminates cholesterol from the brain and retina by metabolism to 24-hydroxycholesterol, thus contributing to cholesterol homeostasis in both organs. 2-Hydroxypropyl-β-cyclodextrin (HPCD), a Food and Drug Admi
Externí odkaz:
https://doaj.org/article/416b987dee114e0eaef22c32059e6f1f
Autor:
Julia V. Busik
Publikováno v:
Journal of Lipid Research, Vol 62, Iss , Pp 100017- (2021)
Abstract: Lipid metabolic abnormalities have emerged as potential risk factors for the development and progression of diabetic complications, including diabetic retinopathy (DR). This review article provides an overview of the results of clinical tri
Externí odkaz:
https://doaj.org/article/eb808d90abe443df8d738b0f5e396a60
Autor:
Martin-Paul Agbaga, Dana K. Merriman, Richard S. Brush, Todd A. Lydic, Shannon M. Conley, Muna I. Naash, Shelley Jackson, Amina S. Woods, Gavin E. Reid, Julia V. Busik, Robert E. Anderson
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 9, Pp 1586-1596 (2018)
Long-chain PUFAs (LC-PUFAs; C20–C22; e.g., DHA and arachidonic acid) are highly enriched in vertebrate retina, where they are elongated to very-long-chain PUFAs (VLC-PUFAs; C ≥28) by the elongation of very-long-chain fatty acids-4 (ELOVL4) enzyme
Externí odkaz:
https://doaj.org/article/a20078d83b14410aaa6495dc9e364840
Autor:
Sandra S. Hammer, Eleni Beli, Nermin Kady, Qi Wang, Kiana Wood, Todd A. Lydic, Goldis Malek, Daniel R. Saban, Xiaoxin X. Wang, Sugata Hazra, Moshe Levi, Julia V. Busik, Maria B. Grant
Publikováno v:
EBioMedicine, Vol 22, Iss C, Pp 181-190 (2017)
Diabetic retinopathy (DR) is a complication secondary to diabetes and is the number one cause of blindness among working age individuals worldwide. Despite recent therapeutic breakthroughs using pharmacotherapy, a cure for DR has yet to be realized.
Externí odkaz:
https://doaj.org/article/f73117b5dd974be191c934e1c359ea8d
Autor:
Qi Wang, Svetlana Navitskaya, Harshini Chakravarthy, Chao Huang, Nermin Kady, Todd A. Lydic, Y. Eugene Chen, Ke-Jie Yin, Folami Lamoke Powell, Pamela M. Martin, Maria B. Grant, Julia V. Busik
Publikováno v:
EBioMedicine, Vol 11, Iss C, Pp 138-150 (2016)
Activation of pro-inflammatory and pro-angiogenic pathways in the retina and the bone marrow contributes to pathogenesis of diabetic retinopathy. We identified miR-15a as key regulator of both pro-inflammatory and pro-angiogenic pathways through dire
Externí odkaz:
https://doaj.org/article/2a68a1d0185d4c5281617ed0199833fd
Autor:
Yan Levitsky, Sandra S. Hammer, Kiera P. Fisher, Chao Huang, Travan L. Gentles, David J. Pegouske, Caimin Xi, Todd A. Lydic, Julia V. Busik, Denis A. Proshlyakov
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 11, p 3830 (2020)
Mitochondrial damage in the cells comprising inner (retinal endothelial cells) and outer (retinal pigment epithelium (RPE)) blood–retinal barriers (BRB) is known to precede the initial BRB breakdown and further histopathological abnormalities in di
Externí odkaz:
https://doaj.org/article/4c6efc89cdb8414285f8aebd844aec08
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 5, p 1693 (2020)
Several studies have suggested that there is a link between membrane attack complex (MAC) deposition in the retina and the progression of diabetic retinopathy (DR). Our recent investigation demonstrated that circulating IgG-laden extracellular vesicl
Externí odkaz:
https://doaj.org/article/5a8239cd07024ff38e4ac489487bc216
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 8, Pp 1797-1809 (2014)
Lipid extraction using a monophasic chloroform/methanol/water mixture, coupled with functional group selective derivatization and direct infusion nano-ESI-high-resolution/accurate MS, is shown to facilitate the simultaneous analysis of both highly po
Externí odkaz:
https://doaj.org/article/84fb513b2aa0473f97d57855798d1739
Autor:
Scott Jewell, Sok Kean Khoo, Nigel Paneth, Kyle A. Furge, Radoslav Z. Nickolov, Karl Dykema, Matthew S. Faber, Julia V. Busik, Nhan T. Ho, James H. Resau
Publikováno v:
International Journal of Molecular Sciences, Vol 13, Iss 8, Pp 9599-9608 (2012)
Screening newborns for treatable serious conditions is mandated in all US states and many other countries. After screening, Guthrie cards with residual blood (whole spots or portions of spots) are typically stored at ambient temperature in many facil
Externí odkaz:
https://doaj.org/article/b5d23bafc4104fa9b80571f6edd38aed
Publikováno v:
Methods in Molecular Biology ISBN: 9781071629659
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5a257bd2ae2c05384af14db1a9fb52d
https://doi.org/10.1007/978-1-0716-2966-6_23
https://doi.org/10.1007/978-1-0716-2966-6_23