Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Julia V, Sopova"'
Autor:
Mikhail S. Bozhokin, Svetlana A. Bozhkova, Julia V. Sopova, Elena R. Mikhailova, Daria V. Marchenko, Mikhail G. Khotin
Publikováno v:
Research Results in Pharmacology, Vol 8, Iss 4, Pp 109-114 (2022)
Introduction: Damage to the hyaline layer of large joints resulting from injuries or age-related changes restricts their mobility. The repair of these disorders is an actual issue in medicine. One of the promising therapies is the usage of cell engin
Externí odkaz:
https://doaj.org/article/01eb493cb72f4ad998e9decb59522010
Publikováno v:
Research Results in Pharmacology, Vol 8, Iss 3, Pp 87-98 (2022)
Novel CRISPR-Cas-based genome editing tools made it feasible to introduce a variety of precise genomic modifications in the pig genome, including introducing multiple edits simultaneously, inserting long DNA sequences into specifically targeted loci,
Externí odkaz:
https://doaj.org/article/36aebfccb79044f8bfe731cb4f94d447
Autor:
Angelina V. Chirinskaite, Alexander Yu. Rotov, Mariia E. Ermolaeva, Lyubov A. Tkachenko, Anastasia N. Vaganova, Lavrentii G. Danilov, Ksenia N. Fedoseeva, Nicolay A. Kostin, Julia V. Sopova, Michael L. Firsov, Elena I. Leonova
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17180 (2023)
Many retinal degenerative diseases result in vision impairment or permanent blindness due to photoreceptor loss or dysfunction. It has been observed that Pde6brd1 mice (rd1), which carry a spontaneous nonsense mutation in the pde6b gene, have a stron
Externí odkaz:
https://doaj.org/article/54aac568102f4810b41b906f5109c84d
Publikováno v:
Research Results in Pharmacology, Vol 8, Iss 2, Pp 1-9 (2022)
Atherosclerosis is a systemic autoimmune disease of the arterial wall characterized by chronic inflammation, high blood pressure, oxidative stress, and progressive loss of cell and organ function with aging. An imbalance of macrophage polarization is
Externí odkaz:
https://doaj.org/article/bce38aeaab5b48db853a596c6a974e38
Autor:
Vasiliy V. Reshetnikov, Angelina V. Chirinskaite, Julia V. Sopova, Roman A. Ivanov, Elena I. Leonova
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Millions of people worldwide have rare genetic diseases that are caused by various mutations in DNA sequence. Classic treatments of rare genetic diseases are often ineffective, and therefore great hopes are placed on gene-editing methods. A DNA base
Externí odkaz:
https://doaj.org/article/6771748e9aad4d3ca1c57fea5f8e602e
Autor:
Vasiliy V. Reshetnikov, Angelina V. Chirinskaite, Julia V. Sopova, Roman A. Ivanov, Elena I. Leonova
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Rare genetic diseases reduce quality of life and can significantly shorten the lifespan. There are few effective treatment options for these diseases, and existing therapeutic strategies often represent only supportive or palliative care. Therefore,
Externí odkaz:
https://doaj.org/article/b845212241964d7681d7ae6c39066ad7
Autor:
Olga A. Krasnova, Karina A. Kulakova, Julia V. Sopova, Evgenyi Y. Smirnov, Sergey A. Silonov, Ekaterina V. Lomert, Olga A. Bystrova, Marina G. Martynova, Irina E. Neganova
Publikováno v:
Cells, Vol 12, Iss 2, p 304 (2023)
G-protein-coupled receptors (GPCRs) are the largest family of cell surface receptors. They modulate key physiological functions and are required in diverse developmental processes including embryogenesis, but their role in pluripotency maintenance an
Externí odkaz:
https://doaj.org/article/ffee20dc86d342718d059c1682310ad0
Autor:
Mariia A. Misiurina, Angelina V. Chirinskaite, Aleksandra S. Fotina, Andrey A. Zelinsky, Julia V. Sopova, Elena I. Leonova
Publikováno v:
Life, Vol 12, Iss 11, p 1927 (2022)
The RNA-guided Cas12a nuclease forms a complex with a CRISPR RNA (crRNA) to cleave the double-stranded DNA target. Among others, Cas12a protein from Lachnospiraceae bacterium (LbCas12a) is widely used for biomedical research. For target recognition,
Externí odkaz:
https://doaj.org/article/60aba87a7791446f8a2fa63310689301
Autor:
Daniel V. Kachkin, Kirill V. Volkov, Julia V. Sopova, Alexander G. Bobylev, Sergei A. Fedotov, Sergei G. Inge-Vechtomov, Oxana V. Galzitskaya, Yury O. Chernoff, Aleksandr A. Rubel, Anna Y. Aksenova
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11657 (2022)
RAD51 is a central protein of homologous recombination and DNA repair processes that maintains genome stability and ensures the accurate repair of double-stranded breaks (DSBs). In this work, we assessed amyloid properties of RAD51 in vitro and in th
Externí odkaz:
https://doaj.org/article/7fefa267ef5c45c699b4d307962d020f
Autor:
Anna V. Glyakina, Constantine D. Pavlov, Julia V. Sopova, Raul R. Gainetdinov, Elena I. Leonova, Oxana V. Galzitskaya
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1, p 209 (2021)
The identification and characterization of ligand-receptor binding sites are important for drug development. Trace amine-associated receptors (TAARs, members of the class A GPCR family) can interact with different biogenic amines and their metabolite
Externí odkaz:
https://doaj.org/article/c03f9d994de6470abe965d8b63382c95