Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Julia V, Bukanova"'
Publikováno v:
Анналы клинической и экспериментальной неврологии, Vol 14, Iss 4, Pp 61-65 (2020)
Introduction. Type A receptors activated by gamma-aminobutyric acid (GABAAR) play an inhibitory role in the nervous system due to the generation of chlorine current (IGABA). Penicillin is a sequential blocker of the GABAAR open channel, which can inh
Externí odkaz:
https://doaj.org/article/a1ee34bd109741f09c7e7b86d4f003ec
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2020)
The ability of androstane and androstene neurosteroids with modifications at C-17, C-5, and C-3 (compounds 1-9) to influence the functional activity of inhibitory glycine and γ-aminobutyric acid (GABA) receptors was estimated. The glycine- and GABA-
Externí odkaz:
https://doaj.org/article/538935fb3d854a4a936e57561bae6033
Publikováno v:
Hippocampus. 32:552-563
The ability of endogenous neurosteroids (NSs) with pregnane skeleton modified at positions C-3 and C-5 to modulate the functional activity of inhibitory glycine receptors (GlyR) and ionotropic ɣ-aminobutyric acid receptors (GABA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e133ff475ff40989ba87d7ed8b0ce32d
https://doi.org/10.1002/hipo.23449
https://doi.org/10.1002/hipo.23449
Publikováno v:
Bulletin of Experimental Biology and Medicine
Ivermectin (IVM) belongs to the class of macrocyclic lactones, which is used as an antiparasitic agent. At present, the researchers focus on possibility to use IVM in treatment of certain forms of cancer and viral diseases such as COVID-19. The mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7bc0181f30c71ba88b25fb922215a07
https://doi.org/10.1007/s10517-021-05125-3
https://doi.org/10.1007/s10517-021-05125-3
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 224
γ-Aminobutyric acid (GABA) is the main inhibitory neurotransmitter. GABA receptor type A (GABA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::96961e3e4ac4dee8e714d7c3b7fe56a5
https://pubmed.ncbi.nlm.nih.gov/35931327
https://pubmed.ncbi.nlm.nih.gov/35931327
Publikováno v:
Bulletin of Experimental Biology and Medicine. 169:791-794
Chloride current (IGly) evoked by the rapid (600 msec) application of glycine on isolated pyramidal neurons of the rat hippocampus was recorded using the patch clamp technique. We studied the effect of individual or combined application of copper ion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::119c7726e722e754c660793071bdc45c
https://doi.org/10.1007/s10517-020-04980-w
https://doi.org/10.1007/s10517-020-04980-w
Publikováno v:
Biomolecules
Volume 11
Issue 6
Biomolecules, Vol 11, Iss 791, p 791 (2021)
Volume 11
Issue 6
Biomolecules, Vol 11, Iss 791, p 791 (2021)
Epipregnanolone (3β-hydroxy-5β-pregnan-20-one, Epi) is an endogenous steroid with important physiological effects and high affinity for GABAA receptors. The effect of Epi on GABA-induced chloride current (IGABA) in native neurons has hardly been st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fecf271eadaede2e884998df483fbf3b
http://europepmc.org/articles/PMC8225200
http://europepmc.org/articles/PMC8225200
Publikováno v:
Neurochemistry International. 118:145-151
The ability of pregnanolone glutamate (PA-Glu), pregnanolone hemisuccinate (PA-hSuc) and pregnanolone hemipimelate (PA-hPim), neuroactive steroids with a negative modulatory effect on excitatory N-methyl- d -aspartate receptors, to influence the func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2630ee427fbdb8c70170f91724718224
https://doi.org/10.1016/j.neuint.2018.06.002
https://doi.org/10.1016/j.neuint.2018.06.002
Publikováno v:
Neurochemistry International. 110:69-74
We have previously shown that application of beta-amyloid peptide 1–42 (Aβ) at picomolar/nanomolar concentrations caused a decrease in the peak amplitude and acceleration of desensitization of the glycine-activated chloride current (IGly) in hippo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f8d13b862b214d94e216e75df3443f7
https://doi.org/10.1016/j.neuint.2017.09.007
https://doi.org/10.1016/j.neuint.2017.09.007
Autor:
Alexey V, Rossokhin, Irina N, Sharonova, Anton, Dvorzhak, Julia V, Bukanova, Vladimir G, Skrebitsky
Publikováno v:
Neuropharmacology. 160
Fenamates mefanamic and niflumic acids (MFA and NFA) induced dual potentiating and inhibitory effects on GABA currents recorded in isolated cerebellar Purkinje cells using the whole-cell patch-clamp and fast-application techniques. Regardless of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::178d059edc46e513105da4ff9bef1a50
https://pubmed.ncbi.nlm.nih.gov/31560908
https://pubmed.ncbi.nlm.nih.gov/31560908