Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Julia Tsai"'
Publikováno v:
Molecular Neurodegeneration, Vol 12, Iss 1, Pp 1-11 (2017)
Abstract Background Microglia are known as resident immune cells in the brain. β-amyloid (Aβ) plaques in the brain of Alzheimer’s disease (AD) are surrounded by microglia, but whether and how microglia affect the formation and maintenance of plaq
Externí odkaz:
https://doaj.org/article/dd5356768565441fb4554f137243e0d6
Autor:
Jacqueline A. French, Elena Cleary, Dennis Dlugos, Gail Farfel, Kathleen Farrell, Barry Gidal, Caitlin L. Grzeskowiak, Rachel Gurrell, Cynthia Harden, Tracy J. Stalvey, Julia Tsai, Elaine C. Wirrell, David Blum, Nathan Fountain
Publikováno v:
Epilepsia. 63:2664-2670
Drug treatment for children with epilepsy should, ideally, be governed by evidence from adequate and well-controlled clinical studies. However, these studies are difficult to conduct, and so direct evidence supporting the informed use of specific dru
Autor:
Murray B. Stein, Thomas D. Geracioti, Cristine Cusin, Xiaoying Sun, Rema Raman, Gail M. Farfel, Jennifer C. Naylor, Christine E. Marx, James B. Lohr, Julia Tsai, Ariel J. Lang, Mark B. Hamner, Ann M. Rasmusson, Sonia Jain, Lanier Summerall, Richard B. Rosse
Publikováno v:
Psychopharmacology. 234:2245-2257
Preclinical and clinical research supports a role for neuroactive steroids in the pathophysiology of posttraumatic stress disorder (PTSD). We investigated ganaxolone (a synthetic 3β-methylated derivative of allopregnanolone, a GABAergic neuroactive
Publikováno v:
Molecular Neurodegeneration, Vol 12, Iss 1, Pp 1-11 (2017)
Molecular Neurodegeneration
Molecular Neurodegeneration
Microglia are known as resident immune cells in the brain. β-amyloid (Aβ) plaques in the brain of Alzheimer’s disease (AD) are surrounded by microglia, but whether and how microglia affect the formation and maintenance of plaques remains controve
Publikováno v:
Epilepsia. 58(4)
Objective To evaluate the efficacy and safety of ganaxolone as adjunctive therapy in adults with uncontrolled partial-onset seizures despite taking up to three concomitant antiepileptic drugs (AEDs). Methods Adults aged 18-69 years and refractory to
Autor:
Allen K. Wensky, Maria Cecilia Garibaldi Marcondes, Jo-Ann Latkowski, Juan J. Lafaille, Glaucia C. Furtado, Julia Tsai
Publikováno v:
The Journal of Immunology. 181:4648-4655
Strong evidence supports that CNS-specific CD4+ T cells are central to the pathogenesis of multiple sclerosis and experimental autoimmune encephalomyelitis (EAE). Using a model of spontaneous EAE, we demonstrated that myelin basic protein (MBP)-speci
Publikováno v:
The Biological Bulletin. 215:143-154
Biofluorescence exists in only a few classes of organisms, with Anthozoa possessing the majority of spe- cies known to express fluorescent proteins. Most species within the Anthozoan subgroup Scleractinia (reef-building corals) not only express green
Autor:
Hung-Teh Kao, David F. Gruber, Julia Tsai, Rob DeSalle, Shelby Sturgis, Vincent A. Pieribone, Douglas J. Davis
Publikováno v:
Marine Biotechnology. 9:733-746
To gain a better understanding of the natural function of fluorescent proteins, we have undertaken quantitative analyses of these proteins in a single species of coral, Montastraea cavernosa, residing around Turneffe atoll, on the Belizean Barrier Re
Publikováno v:
Annals of the New York Academy of Sciences. 1097:30-39
Dystrophic neurites are associated with fibrillar amyloid deposition in Alzheimer's disease (AD), but the frequency and types of changes in synaptic structures near amyloid deposits have not been well characterized. Using high-resolution confocal mic
Autor:
Richard I. Carp, Manik L. Debnath, Henrieta Scholtzova, Li Shao, Chester A. Mathis, Julia Tsai, Wen-Biao Gan, Harry C. Meeker, Pierluigi Gambetti, Joanna Pankiewicz, Marcin Sadowski, William E. Klunk, Thomas Wisniewski, Yong-Sheng Li
Publikováno v:
Scopus-Elsevier
The diagnosis of prion diseases in humans is challenging due to a lack of specific and sensitive non-invasive tests. Many forms of human prion disease including variant Creutzfeldt-Jakob disease (vCJD), Gerstmann-Sträussler-Scheinker (GSS) syndrome,