Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Julia Timár"'
Autor:
Julia Timár, Gábor Polony, Ágnes Szirmai, Ildikó Miklya, Tibor Zelles, Viktória Humli, László Köles, János Farkas, Judit Szepesy, Anita Gáborján, László Tamás, Elek Sylvester Vizi, Tamás Tábi
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 6
International Journal of Molecular Sciences, Vol 22, Iss 2853, p 2853 (2021)
Volume 22
Issue 6
International Journal of Molecular Sciences, Vol 22, Iss 2853, p 2853 (2021)
Age-related hearing loss (ARHL), a sensorineural hearing loss of multifactorial origin, increases its prevalence in aging societies. Besides hearing aids and cochlear implants, there is no FDA approved efficient pharmacotherapy to either cure or prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44a5f61cc938f2145b5111774d049e02
Autor:
Mariana Spetea, Helmut Schmidhammer, Sándor Benyhe, Mihaly Balogh, Mahmoud Al-Khrasani, Pál Riba, Chiara Calabrese, Susanna Fürst, Szilvia B. László, Amir Mohammadzadeh, Zoltán S. Zádori, Ferenc Zádor, Anna Rita Galambos, Kornél Király, Julia Timár, Patrizia Romualdi, Barbara Hutka
Publikováno v:
Molecules
Molecules, Vol 25, Iss 2473, p 2473 (2020)
Molecules, Vol 25, Iss 2473, p 2473 (2020)
There is growing evidence on the role of peripheral µ-opioid receptors (MORs) in analgesia and analgesic tolerance. Opioid analgesics are the mainstay in the management of moderate to severe pain, and their efficacy in the alleviation of pain is wel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9729a11ecb5453a299b4a2a97ce583f6
http://hdl.handle.net/11585/796310
http://hdl.handle.net/11585/796310
Publikováno v:
Behavioural Brain Research. 378:112290
Pharmaceutically available enhancer selegiline/(-)-deprenyl (DEP) in the clinically used dose shows antidepressant effect, but nothing is known about this effect in enhancer dose, and its effect on co-morbid anxiety. Moreover, data about the antidepr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b38acaa22a849da3f0394f085eb85aa
https://doi.org/10.1016/j.bbr.2019.112290
https://doi.org/10.1016/j.bbr.2019.112290
Autor:
Julia Timár, Susanna Gyarmati, Apolka Szentirmay, Pál Riba, Mahmoud Al-Khrasani, Kornél Király, N. Lenkey, Susanna Fürst, T. Friedmann, Erzsébet Lackó, Géza Tóth
Publikováno v:
Brain Research Bulletin. 90:66-71
Since the discovery of opioid receptor dimers their possible roles in opioid actions were intensively investigated. Here we suggest a mechanism that may involve the μ-δ opioid heterodimers. The exact role of δ opioid receptors in antinociception a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::201a2a9d734ecd5e263656ba7f7a2a3d
https://doi.org/10.1016/j.brainresbull.2012.09.006
https://doi.org/10.1016/j.brainresbull.2012.09.006
Autor:
Zoltán S. Zádori, Julia Timár, Tamás Tábi, Zsuzsanna Helyes, Klára Gyires, Viktória E. Tóth, Mahmoud Al-Khrasani, Lutz Hein, Peter Holzer, Zita Puskár, Ágnes Fehér, Márk Kozsurek
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 358(3)
It has been hypothesized that α2-adrenoceptors (α2-ARs) may be involved in the pathomechanism of colitis; however, the results are conflicting because both aggravation and amelioration of colonic inflammation have been described in response to α2-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c93891a4b0603fec8f8fbb29ed167466
https://pubmed.ncbi.nlm.nih.gov/27418171
https://pubmed.ncbi.nlm.nih.gov/27418171
Autor:
Susanna Fürst, Anna Borsodi, Ferenc Zádor, Sándor Benyhe, R. Rapavi, Erzsébet Lackó, Julia Timár, Mahmoud Al-Khrasani, Sándor Hosztafi, András Váradi, Pál Riba, Béla Noszál
Publikováno v:
Current Medicinal Chemistry. 19:4699-4707
The aims of this study were to synthesize 14-O-Methylmorphine-6-O-sulfate (14-O-MeM6SU) and examine its opioid properties (potency, affinity, efficacy) in receptor ligand binding and isolated tissues (mouse vas deferens, MVD and rat vas deferens, RVD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74c2529a0d49633f9de2bf3825756266
https://doi.org/10.2174/092986712803306376
https://doi.org/10.2174/092986712803306376
Autor:
Mahmoud Al-Khrasani, Kornél Király, Melinda Sobor, Julia Timár, Susanna Fürst, Pál Riba, Susanna Gyarmati
Publikováno v:
Behavioural Pharmacology. 21:58-68
This study investigated the behavioural consequences of peri, pre and postnatal morphine (MO) exposure in rats. From gestational day 1 dams were treated with either saline or MO subcutaneously once a day (5 mg/kg on the first 2 days, 10 mg/kg subsequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a373f73ad1211e466fabe98eaf4a615d
https://doi.org/10.1097/fbp.0b013e3283359f39
https://doi.org/10.1097/fbp.0b013e3283359f39
Autor:
Dóra Zelena, Zsuzsanna Fürst, Ágnes Domokos, Csaba Ádori, Zsuzsa Gyarmati, Melinda Sobor, Julia Timár, Gábor B. Makara, Gyorgy Bagdy
Publikováno v:
Behavioural Brain Research. 206:299-309
The recreational party drug "ecstasy" (3,4-methylenedioxymethamphetamine MDMA) is particularly popular among young adults who are in the childbearing age and thus there is a substantial risk of prenatal MDMA exposure. We applied an intermittent treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79d17806cd6e39175fc959bbc51475e8
https://doi.org/10.1016/j.bbr.2009.09.031
https://doi.org/10.1016/j.bbr.2009.09.031
Autor:
Pál Riba, Mahmoud Al-Khrasani, Wioletta Makuch, Susanna Fürst, Ryszard Przewlocki, T. Friedmann, Julia Timár, Helmut Schmidhammer, Ilona Obara, Johannes Schütz, Mariana Spetea, Barbara Przewlocka
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 312:609-618
Opioid analgesics with restricted access to the central nervous system represent a new approach to the treatment of severe pain with an improved safety profile. The objective of this study was to investigate the peripheral and central components of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f88d66531bf8018c7ce1b8ea8fdfe41e
https://doi.org/10.1124/jpet.104.075176
https://doi.org/10.1124/jpet.104.075176
Autor:
Pál Tapolcsányi, Laszlo G. Harsing, Julia Timár, Katalin Nagy, Péter Mátyus, Marko Bernadett Martonne, Andrea Czompa, Szabolcs Udvari, Geza Szabo, Ákos Kocsis, Gabriella Zsilla
Publikováno v:
Current pharmaceutical design. 21(17)
We have synthesized a novel series of N-substituted sarcosines, analogues of NFPS ( N -[3-(biphenyl-4- yloxy)-3-(4-fluorophenyl)propyl]- N -methylglycine), as type-1 glycine transporter (GlyT-1) inhibitors. Several compounds incorporated a diazine ri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc9d6c037b2969402bf15233ad68cc3
https://pubmed.ncbi.nlm.nih.gov/25578890
https://pubmed.ncbi.nlm.nih.gov/25578890