Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Julia T. Arnold"'
Autor:
Manohar S. Gundeti, Julia T. Arnold
Publikováno v:
Journal of Ayurveda and Integrative Medicine, Vol 15, Iss 1, Pp 100907- (2024)
Externí odkaz:
https://doaj.org/article/f42408ae2abf470d8c74c7eb14b06a9d
Autor:
Julia T. Arnold
Publikováno v:
Journal of Ayurveda and Integrative Medicine, Vol 14, Iss 2, Pp 100677- (2023)
The aim of this two-part review in this issue is to provide some basic perspectives from Ayurveda, the traditional medicine of India, and to discuss how current research methodologies may be used to shed light on mechanisms of Ayurvedic treatments to
Externí odkaz:
https://doaj.org/article/58422398a2f64491a4824b5fe60e768b
Autor:
Julia T. Arnold
Publikováno v:
Journal of Ayurveda and Integrative Medicine, Vol 14, Iss 2, Pp 100676- (2023)
Integration of Ayurveda into our current health care research programs is critical to making progress in global wellness and in disease prevention and control, especially for cancer. Ayurveda promotes restoration of the innate healing mechanisms exis
Externí odkaz:
https://doaj.org/article/f4d2f8be8dd3455484be753b7baf0ea9
Autor:
Eric J. Small, Charles L. Sawyers, David W. Goodrich, Richard M. White, Toby T. Hecht, Timothy C. Thompson, Rosalie C. Sears, John K. Lee, Amina Zoubeidi, William L. Dahut, Massimo Loda, Andrew M. Hruszkewycz, Tamara L. Lotan, Daniel W. Lin, Jeffrey Hildesheim, Mark A. Rubin, Jennifer S. Isaacs, Julia T. Arnold, Maria Diaz Meco, Peter S. Nelson, Charles M. Rudin, Himisha Beltran, David R. Rowley, Adam P. Dicker, Max S. Wicha, James L. Gulley, Howard I. Scher, Abdul Tawab-Amiri, Karen E. Knudsen, Michael M. Shen, Evan Y. Yu, Kathleen Kelly
Publikováno v:
Clin Cancer Res
Lineage plasticity has emerged as an important mechanism of treatment resistance in prostate cancer. Treatment-refractory prostate cancers are increasingly associated with loss of luminal prostate markers, and in many cases induction of developmental
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 129:153-162
The reactive stromal phenotype is an important factor for prostate cancer progression and may be a new target for treatment and prevention. A new high efficiency preclinical protocol, the EPI bioassay, reflects the interaction of endocrine, paracrine
Publikováno v:
Carcinogenesis. 32:1648-1654
Transforming growth factor β1 (TGF-β1) increases dehydro-epiandrosterone (DHEA) metabolism to androgens and prostate-specific antigen (PSA) in a prostate tissue model where stromal (6S) cells and epithelial (LAPC-4) cells are cocultured. Red clover
Publikováno v:
The Prostate. 71:766-777
Prostate cancer (PrCa) risk is positively associated with levels of insulin-like growth factor I (IGF-I) and prostate specific antigen (PSA), both androgen receptor (AR) signaling target genes in PrCa cells. Although activated AR is required for andr
Publikováno v:
Endocrinology. 151:1428-1440
beta-Catenin/T-cell factor signaling (beta-CTS) plays multiple critical roles in carcinogenesis and is blocked by androgens in androgen receptor (AR)-responsive prostate cancer (PrCa) cells, primarily via AR sequestration of beta-catenin from T-cell
Autor:
Julia T. Arnold
Publikováno v:
Molecular and Cellular Endocrinology. 301:83-88
Dehydroepiandrosterone (DHEA) is commonly used in the USA as a nutritional supplement for antiaging, metabolic support or other uses. Investigations into understanding the effects of DHEA on human prostate cancer progression have posed more questions
Publikováno v:
Cancer Prevention Research. 2:134-142
Dehydroepiandrosterone (DHEA) is used as a dietary supplement and can be metabolized to androgens and/or estrogens in the prostate. We investigated the hypothesis that DHEA metabolism may be increased in a reactive prostate stroma environment in the