Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Julia Svedova"'
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141548 (2015)
Pathogen and cellular by-products released during infection or trauma are critical for initiating mucosal inflammation. The localization of these factors, their bioactivity and natural countermeasures remain unclear. This concept was studied in mice
Externí odkaz:
https://doaj.org/article/25ef16ae2e52410db1f848cb97151240
Autor:
David N Ruskin, Julia Svedova, Jessica L Cote, Ursula Sandau, Jong M Rho, Masahito Kawamura, Detlev Boison, Susan A Masino
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65021 (2013)
Autism spectrum disorders share three core symptoms: impaired sociability, repetitive behaviors and communication deficits. Incidence is rising, and current treatments are inadequate. Seizures are a common comorbidity, and since the 1920's a high-fat
Externí odkaz:
https://doaj.org/article/d78e51ca8f944864926b40d70458347f
Autor:
Anthony T. Vella, Sanjeev Kumar, Maria M. Xu, Vijay A. K. Rathinam, James A. Buturla, Antoine Ménoret, Julia Svedova
Publikováno v:
Mucosal Immunology. 11:1398-1407
Immune-mediated lung injury is considered the result of an exacerbated innate immune response, although a role for adaptive lymphocytes is emerging. αβ T cells specific for S. aureus enterotoxin A orchestrates a typical innate-like Tγδ17 response
Autor:
Joseph M. Ryan, Julia Svedova, Rebecca Abblett, Adam T. Hagymasi, Matthew P. Hanley, Anthony T. Vella, Steven L. Reiner, Marie-Clare St. Rose, Adam J. Adler, Payal Mittal, Archibald Agyekum-Yamoah
Publikováno v:
The Journal of Immunology. 200:1513-1526
Agonists to the TNF/TNFR costimulatory receptors CD134 (OX40) and CD137 (4-1BB) elicit antitumor immunity. Dual costimulation with anti-CD134 plus anti-CD137 is particularly potent because it programs cytotoxic potential in CD8+ and CD4+ T cells. Cyt
Autor:
Anthony T. Vella, Stephen T. Yeung, Kamal M. Khanna, Antoine Ménoret, Masato Tanaka, Julia Svedova
Publikováno v:
ImmunoHorizons. 1:213-222
Alveolar macrophages (AMs) are considered the first line of defense in the airways. Exposure to harmful substances and certain infections can lead to dysfunction or depletion of AMs. Importantly, these conditions have been associated with increased r
Therapeutic blockade of CD54 attenuates pulmonary barrier damage in T cell-induced acute lung injury
Autor:
Joseph M. Ryan, Anthony T. Vella, Antoine Ménoret, Payal Mittal, Julia Svedova, James A. Buturla
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 313:L177-L191
Acute respiratory distress syndrome (ARDS) is a serious, often fatal condition without available pharmacotherapy. Although the role of innate cells in ARDS has been studied extensively, emerging evidence suggests that T cells may be involved in disea
Publikováno v:
The Journal of Immunology. 196:4510-4521
Staphylococcus aureus enterotoxins cause debilitating systemic inflammatory responses, but how they spread systemically and trigger inflammatory cascade is unclear. In this study, we showed in mice that after inhalation, Staphylococcus aureus enterot
Autor:
Anthony T. Vella, Antoine Ménoret, Julia Svedova, Reinhard Laubenbacher, Jenny E. Suarez-Ramirez, Linda S. Cauley, Naomi Tsurutani, Adam J. Adler, Forrest B. Treadway, Payal Mittal, Soo Mun Ngoi, Marie-Clare St. Rose
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 196(1)
CD134- and CD137-primed CD8 T cells mount powerful effector responses upon recall, but even without recall these dual-costimulated T cells respond to signal 3 cytokines such as IL-12. We searched for alternative signal 3 receptor pathways and found t
Autor:
Joseph Ryan, Payal Mittal, Julia Svedova, Antoine Menoret, Jeffrey S. Wasser, Adam J. Adler, Anthony T. Vella
Publikováno v:
The Journal of Immunology. 198:120.11-120.11
Checkpoint inhibiting antibodies targeting CTLA-4 and PD-1, along with costimulatory agonists, exhibit impressive anticancer efficacy and evidence of durable tumor regression in patients. Despite this success however, many patients fail to respond, l
Autor:
Ursula S. Sandau, Jong M. Rho, Masahito Kawamura, David N. Ruskin, Susan A. Masino, Julia Svedova, Detlev Boison, Jessica L. Cote
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65021 (2013)
PLoS ONE
PLoS ONE
Autism spectrum disorders share three core symptoms: impaired sociability, repetitive behaviors and communication deficits. Incidence is rising, and current treatments are inadequate. Seizures are a common comorbidity, and since the 1920's a high-fat