Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Julia Stellzig"'
Autor:
Andrew M. Kidger, Mark K. Saville, Linda K. Rushworth, Jane Davidson, Julia Stellzig, Motoharu Ono, Ludwig A. Kuebelsbeck, Klaus-Peter Janssen, Bernhard Holzmann, Jennifer P. Morton, Owen J. Sansom, Christopher J. Caunt, Stephen M. Keyse
Publikováno v:
Oncogene. 41:2811-2823
The cytoplasmic phosphatase DUSP6 and its nuclear counterpart DUSP5 are negative regulators of RAS/ERK signalling. Here we use deletion of either Dusp5 or Dusp6 to explore the roles of these phosphatases in a murine model of KRASG12D-driven pancreati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7040fc8693ecb4188b536f1fa542ede0
https://doi.org/10.1038/s41388-022-02302-0
https://doi.org/10.1038/s41388-022-02302-0
Autor:
Andrew M, Kidger, Mark K, Saville, Linda K, Rushworth, Jane, Davidson, Julia, Stellzig, Motoharu, Ono, Ludwig A, Kuebelsbeck, Klaus-Peter, Janssen, Bernhard, Holzmann, Jennifer P, Morton, Owen J, Sansom, Christopher J, Caunt, Stephen M, Keyse
Publikováno v:
Oncogene. 41(20)
The cytoplasmic phosphatase DUSP6 and its nuclear counterpart DUSP5 are negative regulators of RAS/ERK signalling. Here we use deletion of either Dusp5 or Dusp6 to explore the roles of these phosphatases in a murine model of KRAS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2809ff027699cd28e48ce0911416b762
https://pubmed.ncbi.nlm.nih.gov/35418690
https://pubmed.ncbi.nlm.nih.gov/35418690
Autor:
Julia Stellzig, Linda K. Rushworth, Cassidy Bayley, Stephen M. Keyse, Jane Davidson, Andrew M. Kidger, Edward Caddye, Tim Rogers, Christopher J. Caunt, Christopher J. Bryant
Publikováno v:
Proceedings of the National Academy of Sciences. 114
Deregulated extracellular signal-regulated kinase (ERK) signaling drives cancer growth. Normally, ERK activity is self-limiting by the rapid inactivation of upstream kinases and delayed induction of dual-specificity MAP kinase phosphatases (MKPs/DUSP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ad239ff65bc1a741d9cf1e7b1161eea
https://doi.org/10.1073/pnas.1614684114
https://doi.org/10.1073/pnas.1614684114
Autor:
Maren Scharfe, Michael Kracht, Liane Jurida, Knut Beuerlein, Katja Handschick, M. Lienhard Schmitz, Julia Stellzig, Michael Jarek, Marek Bartkuhn, Oliver Dittrich-Breiholz, Axel Weber, Johanna Soelch, Helmut Müller, Heike Schneider
Publikováno v:
Molecular cell. 53(2)
Given the intimate link between inflammation and dysregulated cell proliferation in cancer, we investigated cytokine-triggered gene expression in different cell cycle stages. Transcriptome analysis revealed that G1 release through cyclin-dependent ki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::147c7ae841524d950e0f44b81876034f
https://pubmed.ncbi.nlm.nih.gov/24389100
https://pubmed.ncbi.nlm.nih.gov/24389100
Autor:
Andreas Vilcinskas, Eileen Knorr, Kristine Weber, Stefanie Grünwald, Julia Stellzig, Uwe Wenzel, Michael Boll, Iris V. Adam, Sarai Binger, Richard M. Twyman
Diet is generally believed to affect the aging process. The effects of complex foods on life span can be investigated using simple models that produce rapid results and allow the identification of food–gene interactions. Here, we show that 1 % lyop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21818adcb404d6c329439afc684d40c9
https://publica.fraunhofer.de/handle/publica/244103
https://publica.fraunhofer.de/handle/publica/244103
Autor:
T Acker, Kateryna Shostak, S Ismail Göktuna, Julia Stellzig, Michael Schmitz, Florian Renner, Alain Chariot, Axel Pagenstecher
Publikováno v:
Oncogenesis
Signal transmission by the noncanonical IkappaB kinases (IKKs), TANK-binding kinase 1 (TBK1) and IKKɛ, requires interaction with adapter proteins such as TRAF associated NF-κB activator (TANK). Although increased expression or dysregulation of both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7477254ab96142b8c76174bcadce6c30
https://doi.org/10.1038/oncsis.2013.42
https://doi.org/10.1038/oncsis.2013.42