Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Julia Steinmetz-Späh"'
Autor:
Ahlem Zaghmi, Erdem Aybay, Long Jiang, Mingmei Shang, Julia Steinmetz‐Späh, Fredrik Wermeling, Per Kogner, Marina Korotkova, Päivi Östling, Per‐Johan Jakobsson, Brinton Seashore‐Ludlow, Karin Larsson
Publikováno v:
Molecular Oncology, Vol 18, Iss 2, Pp 317-335 (2024)
High‐throughput drug screening enables the discovery of new anticancer drugs. Although monolayer cell cultures are commonly used for screening, their limited complexity and translational efficiency require alternative models. Three‐dimensional ce
Externí odkaz:
https://doaj.org/article/4a29d39e06f844be8b5afb223e6cda70
Autor:
Julia Steinmetz-Späh, Jianyang Liu, Rajkumar Singh, Maria Ekoff, Sanjaykumar Boddul, Xiao Tang, Filip Bergqvist, Helena Idborg, Pascal Heitel, Elin Rönnberg, Daniel Merk, Fredrik Wermeling, Jesper Z. Haeggström, Gunnar Nilsson, Dieter Steinhilber, Karin Larsson, Marina Korotkova, Per-Johan Jakobsson
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 12, Pp 100310- (2022)
Inhibition of microsomal prostaglandin E synthase-1 (mPGES-1) results in decreased production of proinflammatory PGE2 and can lead to shunting of PGH2 into the prostaglandin D2 (PGD2)/15-deoxy-Δ12,14-prostaglandin J2 (15dPGJ2) pathway. 15dPGJ2 forms
Externí odkaz:
https://doaj.org/article/21de76dd4fea476cb4a8cc5faaeadde7
Autor:
Andreas Weigert, Bernhard Brüne, Kathi Zarnack, Florian R. Greten, Ingrid Fleming, Emmanouil Fokas, Rajkumar Savai, Julia Steinmetz-Späh, Rolf Nüsing, Dominique Thomas, Elise Gradhand, Yannick Schreiber, Adele M. Nicolas, Rüdiger Popp, Timo Frömel, Yingying Han, Mohammed A.F. Elewa, Olga Lityagina, Jessica Wagih, Mirko Brüggemann, Eiman Elwakeel
The activation and differentiation of cancer-associated fibroblasts (CAF) are involved in tumor progression. Here, we show that the tumor-promoting lipid mediator prostaglandin E2 (PGE2) plays a paradoxical role in CAF activation and tumor progressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a7b802012bd65a8c046cd26a1a92ab1
https://doi.org/10.1158/0008-5472.c.6513943.v1
https://doi.org/10.1158/0008-5472.c.6513943.v1
Autor:
Andreas Weigert, Bernhard Brüne, Kathi Zarnack, Florian R. Greten, Ingrid Fleming, Emmanouil Fokas, Rajkumar Savai, Julia Steinmetz-Späh, Rolf Nüsing, Dominique Thomas, Elise Gradhand, Yannick Schreiber, Adele M. Nicolas, Rüdiger Popp, Timo Frömel, Yingying Han, Mohammed A.F. Elewa, Olga Lityagina, Jessica Wagih, Mirko Brüggemann, Eiman Elwakeel
Supplementary Figure from Disruption of Prostaglandin E2 Signaling in Cancer-Associated Fibroblasts Limits Mammary Carcinoma Growth but Promotes Metastasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5719082b5ce08442cd0f36e065c7f83b
https://doi.org/10.1158/0008-5472.22431586
https://doi.org/10.1158/0008-5472.22431586
Autor:
Andreas Weigert, Bernhard Brüne, Kathi Zarnack, Florian R. Greten, Ingrid Fleming, Emmanouil Fokas, Rajkumar Savai, Julia Steinmetz-Späh, Rolf Nüsing, Dominique Thomas, Elise Gradhand, Yannick Schreiber, Adele M. Nicolas, Rüdiger Popp, Timo Frömel, Yingying Han, Mohammed A.F. Elewa, Olga Lityagina, Jessica Wagih, Mirko Brüggemann, Eiman Elwakeel
Supplementary Table from Disruption of Prostaglandin E2 Signaling in Cancer-Associated Fibroblasts Limits Mammary Carcinoma Growth but Promotes Metastasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1232489ab941377d305e4044a8500bc8
https://doi.org/10.1158/0008-5472.22431577.v1
https://doi.org/10.1158/0008-5472.22431577.v1
Autor:
Yuze Zhang, Julia Steinmetz‐Späh, Helena Idborg, Liyuan Zhu, Huihui Li, Haojie Rao, Zengrong Chen, Ziyi Guo, Lejia Hu, Chuansheng Xu, Hong Chen, Marina Korotkova, Per‐Johan Jakobsson, Miao Wang
Publikováno v:
British Journal of Pharmacology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c28c1dfbfe723fbdb9f84f2cb94b59fc
https://doi.org/10.1111/bph.16061
https://doi.org/10.1111/bph.16061
Autor:
Per-Johan Jakobsson, Karin Larsson, Peter Stenvinkel, Jabin Jahan, Neja Mudrovcic, Karolina Kublickiene, Marina Korotkova, Lars Wennberg, Julia Steinmetz-Späh, Samsul Arefin
Publikováno v:
British Journal of Pharmacology. 179:1433-1449
Background Inhibition of the microsomal prostaglandin (PG) E2 synthase (mPGES-1) introduces a promising anti-inflammatory treatment approach by specifically reducing PGE2 . The microvasculature is a central target organ for early manifestations of ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf13620c65e80b40698484590b5755ba
https://doi.org/10.1111/bph.15729
https://doi.org/10.1111/bph.15729
Autor:
Jianyang Liu, Bing Peng, Julia Steinmetz-Späh, Helena Idborg, Marina Korotkova, Per-Johan Jakobsson
Publikováno v:
Prostaglandins & Other Lipid Mediators. 167:106738
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8c8c9a8b93a4ed18da1b2aa557612f1
https://doi.org/10.1016/j.prostaglandins.2023.106738
https://doi.org/10.1016/j.prostaglandins.2023.106738
Autor:
Eiman Elwakeel, Mirko Brüggemann, Jessica Wagih, Olga Lityagina, Mohammed A.F. Elewa, Yingying Han, Timo Frömel, Rüdiger Popp, Adele M. Nicolas, Yannick Schreiber, Elise Gradhand, Dominique Thomas, Rolf Nüsing, Julia Steinmetz-Späh, Rajkumar Savai, Emmanouil Fokas, Ingrid Fleming, Florian R. Greten, Kathi Zarnack, Bernhard Brüne, Andreas Weigert
Publikováno v:
Cancer research. 82(7)
The activation and differentiation of cancer-associated fibroblasts (CAF) are involved in tumor progression. Here, we show that the tumor-promoting lipid mediator prostaglandin E2 (PGE2) plays a paradoxical role in CAF activation and tumor progressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83c8edb5c148c5bad3032d836c0e3f59
https://pubmed.ncbi.nlm.nih.gov/35105690
https://pubmed.ncbi.nlm.nih.gov/35105690