Zobrazeno 1 - 2
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pro vyhledávání: '"Julia Steckner"'
Autor:
Duncan W. S. MacKenzie, Anna Schaefer, Julia Steckner, Christopher A. Leo, Dalia Naser, Efrosini Artikis, Aron Broom, Travis Ko, Purnank Shah, Mikaela Q. Ney, Elisa Tran, Martin T. J. Smith, Brian Fuglestad, A. Joshua Wand, Charles L. Brooks, Elizabeth M. Meiering
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(26)
Allostery is the phenomenon of coupling between distal binding sites in a protein. Such coupling is at the crux of protein function and regulation in a myriad of scenarios, yet determining the molecular mechanisms of coupling networks in proteins rem
Autor:
Kyle Trainor, Colleen M. Doyle, Avril Metcalfe-Roach, Julia Steckner, Daša Lipovšek, Heather Malakian, David Langley, Stanley R. Krystek Jr., Elizabeth M. Meiering
Publikováno v:
Journal of molecular biology. 434(2)
Structural heterogeneity often constrains the characterization of aggregating proteins to indirect or low-resolution methods, obscuring mechanistic details of association. Here, we report progress in understanding the aggregation of Adnectins, engine