Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Julia Schuld"'
Autor:
Alexander Schaiter, Andreas Hentschel, Felix Kleefeld, Julia Schuld, Vincent Umathum, Tara Procida-Kowalski, Christopher Nelke, Angela Roth, Andreas Hahn, Heidrun H. Krämer, Tobias Ruck, Rita Horvath, Peter F. M. van der Ven, Marek Bartkuhn, Andreas Roos, Anne Schänzer
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract To gain a deeper understanding of skeletal muscle function in younger age and aging in elderly, identification of molecular signatures regulating these functions under physiological conditions is needed. Although molecular studies of healthy
Externí odkaz:
https://doaj.org/article/194ae0f583e44868afbde68598f4c31c
Autor:
Keerthika Lohanadan, Marvin Assent, Anja Linnemann, Julia Schuld, Lukas C. Heukamp, Karsten Krause, Matthias Vorgerd, Jens Reimann, Anne Schänzer, Gregor Kirfel, Dieter O. Fürst, Peter F. M. Van der Ven
Publikováno v:
Cells, Vol 13, Iss 1, p 85 (2023)
Synaptopodin-2 (SYNPO2) is a protein associated with the Z-disc in striated muscle cells. It interacts with α-actinin and filamin C, playing a role in Z-disc maintenance under stress by chaperone-assisted selective autophagy (CASA). In smooth muscle
Externí odkaz:
https://doaj.org/article/d61f3e09ff804350af78d9e5e1d5ffbd
Autor:
Kenichi Kimura, Astrid Ooms, Kathrin Graf-Riesen, Maithreyan Kuppusamy, Andreas Unger, Julia Schuld, Jan Daerr, Achim Lother, Caroline Geisen, Lutz Hein, Satoru Takahashi, Guang Li, Wilhelm Röll, Wilhelm Bloch, Peter F. M. van der Ven, Wolfgang A. Linke, Sean M. Wu, Pitter F. Huesgen, Jörg Höhfeld, Dieter O. Fürst, Bernd K. Fleischmann, Michael Hesse
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
An amino acid exchange (P209L) in the human co-chaperone BAG3 gives rise to severe childhood restrictive cardiomyopathy. Here the authors describe humanized transgenic mouse models which phenocopy the disease and provide insight into the pathogenic m
Externí odkaz:
https://doaj.org/article/6cdac892607d45f6a6225c942b322a42
Autor:
Julia Schuld, Zacharias Orfanos, Frédéric Chevessier, Britta Eggers, Lorena Heil, Julian Uszkoreit, Andreas Unger, Gregor Kirfel, Peter F. M. van der Ven, Katrin Marcus, Wolfgang A. Linke, Christoph S. Clemen, Rolf Schröder, Dieter O. Fürst
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-19 (2020)
Abstract Filamin C (FLNc) is mainly expressed in striated muscle cells where it localizes to Z-discs, myotendinous junctions and intercalated discs. Recent studies have revealed numerous mutations in the FLNC gene causing familial and sporadic myopat
Externí odkaz:
https://doaj.org/article/ba3e1050cbf146d9a4a94ff8ab249a1a
Publikováno v:
Cell and Tissue Research.
Variations in the gene encoding filamin-A-interacting protein 1 (FILIP1) were identified to be associated with a combination of neurological and muscular symptoms. While FILIP1 was shown to regulate motility of brain ventricular zone cells, a process
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::776ed5661bca627b1ff40eb1fd4d6b6b
https://doi.org/10.1007/s00441-023-03776-4
https://doi.org/10.1007/s00441-023-03776-4
Autor:
A. Sprengel, Stefan Rupp, S. Gräf, Anne Schänzer, Diana Zengeler, Julia Schuld, Andreas Hahn, Peter F.M. van der Ven, Elisabeth Schumann, Giovanni Maroli, Lisann Gulatz, Uwe Ahting, Till Acker, Christian Jux, Dieter O. Fürst
Publikováno v:
Journal of muscle research and cell motility. 42(2)
Hypertrophic cardiomyopathy (HCM) often leads to heart failure. Mutations in sarcomeric proteins are most frequently the cause of HCM but in many patients the gene defect is not known. Here we report on a young man who was diagnosed with HCM shortly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3dd4d23292fb43d2f177f8a104cb804
https://pubmed.ncbi.nlm.nih.gov/33710525
https://pubmed.ncbi.nlm.nih.gov/33710525
Autor:
Julia Schuld, Wolfgang A. Linke, Gregor Kirfel, Pfm van der Ven, Zacharias Orfanos, K Markus, Frédéric Chevessier, Britta Eggers, Andreas Unger, Christoph S. Clemen, Dieter O. Fürst, Rolf Schröder
Publikováno v:
Nervenheilkunde.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f312497fd3b10b7ef4aa09561fb87b4a
https://doi.org/10.1055/s-0039-1684974
https://doi.org/10.1055/s-0039-1684974
Autor:
Markus Linhart, Julia Schuld, Peter F.M. van der Ven, Jan W. Schrickel, Zacharias Orfanos, Sied Kebir, Rainer Meyer, Dieter O. Fürst, Gregor Kirfel, Christian Lamberz
Publikováno v:
Experimental Cell Research. 348:95-105
Pressure overload induces cardiac remodeling involving both the contractile machinery and intercalated disks (IDs). Filamin C (FlnC) and Xin actin-binding repeat-containing proteins (XIRPs) are multi-adapters localizing in IDs of higher vertebrates.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f36074746b28938c869e4417b536e438
https://doi.org/10.1016/j.yexcr.2016.09.008
https://doi.org/10.1016/j.yexcr.2016.09.008
Autor:
Anne-C. Plank, Peter F.M. van der Ven, Ursula Schlötzer-Schrehardt, Lucie Wolf, Frédéric Chevessier, Dieter O. Fürst, Andreas Unger, Zacharias Orfanos, A. Maerkens, Matthias Vorgerd, Stephan von Hörsten, Julia Schuld, Rudolf A. Kley, Rolf Schröder, Wolfgang A. Linke, Katrin Marcus
Publikováno v:
Human Molecular Genetics. 24:7207-7220
Filamin C (FLNC) mutations in humans cause myofibrillar myopathy (MFM) and cardiomyopathy, characterized by protein aggregation and myofibrillar degeneration. We generated the first patient-mimicking knock-in mouse harbouring the most common disease-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f112b89cf194271c8dbce82877a50791
https://doi.org/10.1093/hmg/ddv421
https://doi.org/10.1093/hmg/ddv421
Autor:
Dieter O. Fürst, Gregor Kirfel, P.F.M. van der Ven, Zacharias Orfanos, Andreas Unger, Christoph S. Clemen, Wolfgang A. Linke, Julia Schuld, Rolf Schröder, Frédéric Chevessier
Publikováno v:
Neuromuscular Disorders. 29:S63
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe89702ccff33f038d6001e942389449
https://doi.org/10.1016/j.nmd.2019.06.107
https://doi.org/10.1016/j.nmd.2019.06.107