Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Julia Schenkel"'
Autor:
Athanassios Fragoulis, Julia Schenkel, Nicole Schröder, Elisa Fabiana Brandt, Mathias Weiand, Tabita Neu, Pierluigi Ramadori, Tim Caspers, Sebastian Kant, Thomas Pufe, Antje Mohs, Christian Trautwein, Thomas Longerich, Konrad Ludwig Streetz, Christoph Jan Wruck
Publikováno v:
Redox Biology, Vol 57, Iss , Pp 102453- (2022)
The Nrf2 signaling pathway prevents cancer initiation, but genetic mutations that activate this pathway are found in various types of cancer. The molecular mechanisms underlying this Janus-headed character are still not understood. Here, we show that
Externí odkaz:
https://doaj.org/article/35f88a8c68d341b194b2737c0657a5de
Autor:
Athanassios Fragoulis, Julia Schenkel, Nicole Schröder, Elisa Fabiana Brandt, Mathias Weiand, Tabita Neu, Pierluigi Ramadori, Tim Caspers, Sebastian Kant, Thomas Pufe, Antje Mohs, Christian Trautwein, Thomas Longerich, Konrad Ludwig Streetz, Christoph Jan Wruck
Publikováno v:
Redox biology. 57
The Nrf2 signaling pathway prevents cancer initiation, but genetic mutations that activate this pathway are found in various types of cancer. The molecular mechanisms underlying this Janus-headed character are still not understood. Here, we show that
Autor:
Christoph Jan Wruck, Tim Schellenberg, Athanassios Fragoulis, Thomas W. Kensler, Miriam Herzog, Christian Trautwein, Konrad L. Streetz, Julia Schenkel, Thomas Pufe, Holger Jahr
Publikováno v:
Toxicol Sci
The Nrf2 pathway protects against oxidative stress and induces regeneration of various tissues. Here, we investigated whether Nrf2 protects from sclerosing cholangitis and biliary fibrosis and simultaneously induces liver regeneration. Diet containin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7897d3c07114b27afc3eb22de39a5287
https://europepmc.org/articles/PMC6542338/
https://europepmc.org/articles/PMC6542338/
Autor:
Julia Schenkel, Christoph Jan Wruck, Thomas W. Kensler, Fabienne Schumacher, Hannah K. Drescher, Pierluigi Ramadori, Cordula Berger, Athanassios Fragoulis, S Erschfeld, Christian Trautwein, Konrad L. Streetz, Daniela C. Kroy
Publikováno v:
Free Radical Biology and Medicine. 91:114-126
Generation of reactive oxygen species (ROS) in response to fatty acids accumulation has been classically proposed as a possible "second hit" triggering progression from simple steatosis to non-alcoholic steatohepatitis (NASH). In this study we challe