Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Julia Saifetiarova"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Mutations in human tuberous sclerosis complex (TSC) genes TSC1 and TSC2 are the leading causes of developmental brain abnormalities and large tumors in other tissues. Murine Tsc1/2 have been shown to negatively regulate the mammalian target of rapamy
Externí odkaz:
https://doaj.org/article/ef62f9b7a07c426d842645be6aadb455
Autor:
Anand V.R. Kornepati, Jacob T. Boyd, Clare E. Murray, Julia Saifetiarova, Bárbara de la Peña Avalos, Cody M. Rogers, Haiyan Bai, Alvaro S. Padron, Yiji Liao, Carlos Ontiveros, Robert S. Svatek, Robert Hromas, Rong Li, Yanfen Hu, Jose R. Conejo-Garcia, Ratna K. Vadlamudi, Weixing Zhao, Eloïse Dray, Patrick Sung, Tyler J. Curiel
Publikováno v:
Cancer Res
BRCA1-mediated homologous recombination is an important DNA repair mechanism that is the target of FDA-approved PARP inhibitors, yet details of BRCA1-mediated functions remain to be fully elucidated. Similarly, immune checkpoint molecules are targets
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::221a8b87abc3a84558953b2ec9728da2
https://doi.org/10.1158/0008-5472.can-21-2076
https://doi.org/10.1158/0008-5472.can-21-2076
Publikováno v:
The Journal of Neuroscience. 38:6267-6282
Disorganization of nodes of Ranvier is associated with motor and sensory dysfunctions. Mechanisms that allow nodal recovery during pathological processes remain poorly understood. A highly enriched nodal cytoskeletal protein βIV spectrin anchors and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2779cb5ff6da1801760c39627c0ee8e
https://doi.org/10.1523/jneurosci.0515-18.2018
https://doi.org/10.1523/jneurosci.0515-18.2018
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports
Scientific Reports
The roles of myelin in maintaining axonal integrity and action potential (AP) propagation are well established, but its role in synapse maintenance and neurotransmission remains largely understudied. Here, we investigated how Purkinje axon myelinatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50323c41656aa17dcdb215a1b0107d56
http://link.springer.com/article/10.1038/s41598-018-19314-0
http://link.springer.com/article/10.1038/s41598-018-19314-0
Publikováno v:
Journal of Neuroscience Research. 95:1373-1390
Bidirectional interactions between neurons and myelinating glial cells result in formation of axonal domains along myelinated fibers. Loss of axonal domains leads to detrimental consequences on nerve structure and function, resulting in reduced condu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3f558f5cf5e48faafb86b98cfd7ebeb
https://doi.org/10.1002/jnr.24052
https://doi.org/10.1002/jnr.24052
Publikováno v:
The Journal of Neuroscience. 37:2524-2538
The mechanisms that govern node of Ranvier organization, stability, and long-term maintenance remain to be fully elucidated. One of the molecular components of the node is the cytoskeletal scaffolding protein, ankyrin G (AnkG), which interacts with m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e73176c8ccf013096cc83c0538958176
https://doi.org/10.1523/jneurosci.2661-16.2017
https://doi.org/10.1523/jneurosci.2661-16.2017
Autor:
Julia Saifetiarova, Manzoor A. Bhat
Publikováno v:
Journal of neuroscience research. 97(3)
The cerebellar cortex receives neural information from other brain regions to allow fine motor coordination and motor learning. The primary output neurons from the cerebellum are the Purkinje neurons that transmit inhibitory responses to deep cerebel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf50f14d68c5af1f4dd30fde9c7f2953
https://pubmed.ncbi.nlm.nih.gov/30447021
https://pubmed.ncbi.nlm.nih.gov/30447021
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 38(28)
Disorganization of nodes of Ranvier is associated with motor and sensory dysfunctions. Mechanisms that allow nodal recovery during pathological processes remain poorly understood. A highly enriched nodal cytoskeletal protein βIV spectrin anchors and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7e996138811ccec570f9d09da890da99
https://pubmed.ncbi.nlm.nih.gov/30602540
https://pubmed.ncbi.nlm.nih.gov/30602540
Publikováno v:
Frontiers in Cellular Neuroscience
Intricate molecular interactions between neurons and glial cells underlie the creation of unique domains that are essential for saltatory conduction of action potentials by myelinated axons. Previously, the cell surface adhesion molecule Neurofascin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f17eb94b00ac75dcbfae6b7ad14c07e
https://doi.org/10.3389/fncel.2017.00011
https://doi.org/10.3389/fncel.2017.00011
Publikováno v:
Journal of neuroscience research. 95(7)
Bidirectional interactions between neurons and myelinating glial cells result in formation of axonal domains along myelinated fibers. Loss of axonal domains leads to detrimental consequences on nerve structure and function, resulting in reduced condu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f67129beb60d0150f8cb74e4ff9b5340
https://pubmed.ncbi.nlm.nih.gov/28370195
https://pubmed.ncbi.nlm.nih.gov/28370195