Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Julia Sacherl"'
Autor:
Hristo L. Svilenov, Romina Bester, Julia Sacherl, Ramona Absmeier, Carsten Peters, Ulrike Protzer, Carsten Brockmeyer, Johannes Buchner
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-7 (2022)
Fusion of ACE2 to IgM-Fc results in hexameric ACE2-IgM-Fc proteins with potent virus neutralization efficiency of patient-isolated SARS-CoV and SARS-CoV-2 variants.
Externí odkaz:
https://doaj.org/article/531c1bbc362d430f988e33a1452a8425
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Certain bovine antibodies have ultra-long long complementarity-determining regions (CDRs) that contain a knob for antigen interaction, which is connected to the antibody through a stalk. Here, the authors combine biophysical experiments and MD simula
Externí odkaz:
https://doaj.org/article/551d369430b84beb8602ae26a8e6b65f
Autor:
Julia Sacherl, Anna D. Kosinska, Kristina Kemter, Martin Kächele, Sabine C. Laumen, Hélène A. Kerth, Edanur Ates Öz, Lisa S. Wolff, Jinpeng Su, Sandra Essbauer, Gerd Sutter, Martin Scholz, Katrin Singethan, Jens Altrichter, Ulrike Protzer
Publikováno v:
JHEP Reports. 5:100603
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4df4703a7f0cd2ce25bafd717d6a5785
https://doi.org/10.1016/j.jhepr.2022.100603
https://doi.org/10.1016/j.jhepr.2022.100603
Autor:
Martin A. Mück-Häusl, Ulrike Protzer, Simon P. Fräßle, Karin Wisskirchen, Dirk H. Busch, Marvin M. Festag, Julia Festag, Julia Sacherl, Theresa Asen, Sophia Schreiber
Publikováno v:
Mol. Ther. 27, 947-959 (2019)
Mol Ther
Mol Ther
Chimeric antigen receptor (CAR) T cell therapy is a promising novel therapeutic approach for cancer but also for chronic infection. We have developed a fully human, second-generation CAR directed against the envelope protein of hepatitis B virus on t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00c4ea5760fff97a948feee043d0c961
https://doi.org/10.1016/j.ymthe.2019.02.001
https://doi.org/10.1016/j.ymthe.2019.02.001
Autor:
Hristo Svilenov, Julia Sacherl, Alwin Reiter, Lisa Wolff, Cho-Chin Cheng, Marcel Stern, Vincent Grass, Frank-Peter Wachs, Nicole Simonavicius, Susanne Pippig, Florian Wolschin, Oliver Keppler, Johannes Buchner, Carsten Brockmeyer, Ulrike Protzer
SARS-CoV-2 enters host cells after binding through its spike glycoprotein to the angiotensin-converting enzyme 2 (ACE2) receptor. Soluble ACE2 ectodomains bind and neutralize the virus, yet their short in vivo half-live limits their therapeutic use.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43ce5133c49fd0f400f79469b14d13e4
https://doi.org/10.21203/rs.3.rs-459941/v1
https://doi.org/10.21203/rs.3.rs-459941/v1
Autor:
Alwin Reiter, Hristo L. Svilenov, Nicole Simonavicius, Susanne Pippig, Vincent Grass, Lisa S. Wolff, Marcel Stern, Ulrike Protzer, Oliver T. Keppler, Frank-Peter Wachs, Julia Sacherl, Johannes Buchner, Martin Feuerherd, Florian Wolschin, Carsten Brockmeyer, Cho-Chin Cheng
Publikováno v:
ANTIVIRAL RESEARCH
Antiviral Research
Antiviral Res. 196:105197 (2021)
Antiviral Research
Antiviral Res. 196:105197 (2021)
SARS-CoV-2 enters host cells after binding through its spike glycoprotein to the angiotensin-converting enzyme 2 (ACE2) receptor. Soluble ACE2 ectodomains bind and neutralize the virus, yet their short in vivo half-live limits their therapeutic use.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a6c9fd0742e89521da950ce22f0b476
https://hdl.handle.net/1854/LU-8741219
https://hdl.handle.net/1854/LU-8741219
Autor:
Johannes Buchner, Frank-Peter Wachs, Lisa S. Wolff, Julia Sacherl, Hristo L. Svilenov, Marcel Stern, Ulrike Protzer, Nicole Simonavicius, Carsten Brockmeyer, Cho-Chin Chen, Florian Wolschin, Susanne Pippig, Alwin Reiter
The novel severe acute respiratory syndrome (SARS)-like coronavirus (SARS-CoV-2) enters its host cells after binding to the angiotensin-converting enzyme 2 (ACE2)viaits spike glycoprotein. This interaction is critical for virus entry and virus-host m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c54147b1b47920e1bab5b7ab655a94c
https://doi.org/10.1101/2020.12.06.413443
https://doi.org/10.1101/2020.12.06.413443
Autor:
Romina Bester, Xue Zhou, Julia Sacherl, Ulrike Protzer, Lu Gao, Florian W. R. Vondran, Chunkyu Ko, Christoph K. Blossey, Zhiheng Xu
Publikováno v:
Antimicrobial Agents and Chemotherapy
Antimicrob. Agents Chemother. 64:e01440-19 (2019)
Antimicrob Agents Chemother
Antimicrob. Agents Chemother. 64:e01440-19 (2019)
Antimicrob Agents Chemother
Hepatitis B virus (HBV) is a major human pathogen, killing an estimated 887,000 people per year. Therefore, potentially curative therapies are of high importance. Following infection, HBV deposits a covalently closed circular DNA (cccDNA) in the nucl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c6f11354484a967d8f9192e249572c7
Autor:
Ulrike Portzer, Livia Brunner, Julia Sacherl, Anna Kosinska, Frank Thiele, Jinpeng Su, Nicolas Collin, Julia Hasreiter, Géraldine Frank, Katrin Singethan
Publikováno v:
Journal of Hepatology. 70:e485-e486
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0947091d63a38c2af1354aaa9f095d99
https://doi.org/10.1016/s0618-8278(19)30954-5
https://doi.org/10.1016/s0618-8278(19)30954-5
Publikováno v:
Journal of Biological Chemistry. 289:25250-25261
The molecular chaperone Hsc70 assists in the folding of non-native proteins together with its J domain- and BAG domain-containing cofactors. In Caenorhabditis elegans, two BAG domain-containing proteins can be identified, one of them being UNC-23, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d65da445b97d38e8a35c60e1a061d103
https://doi.org/10.1074/jbc.m114.565234
https://doi.org/10.1074/jbc.m114.565234