Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Julia Ring"'
Autor:
Jelena Tadic, Julia Ring, Andrea Jerkovic, Selena Ristic, Marta Maglione, Jörn Dengjel, Stephan J. Sigrist, Tobias Eisenberg
Publikováno v:
Cell Stress, Vol 6, Iss 5, Pp 61-64 (2022)
Alzheimer’s disease (AD) is the most common form of dementia with millions of people affected worldwide. Pathophysiological manifestations of AD include the extracellular accumulation of amyloid beta (Abeta) pep-tides, products of the proteolytic c
Externí odkaz:
https://doaj.org/article/c44ddf419ff94f3e8badbc73098e7b34
Autor:
Julia Ring, Jelena Tadic, Selena Ristic, Michael Poglitsch, Martina Bergmann, Nemanja Radic, Dirk Mossmann, YongTian Liang, Marta Maglione, Andrea Jerkovic, Roozbeh Hajiraissi, Marcel Hanke, Victoria Küttner, Heimo Wolinski, Andreas Zimmermann, Lana Domuz Trifunović, Leonie Mikolasch, Daiana N Moretti, Filomena Broeskamp, Julia Westermayer, Claudia Abraham, Simon Schauer, Christopher Dammbrueck, Sebastian J Hofer, Mahmoud Abdellatif, Guido Grundmeier, Guido Kroemer, Ralf J Braun, Niklas Hansen, Cornelia Sommer, Mirjana Ninkovic, Sandra Seba, Patrick Rockenfeller, Friederike‐Nora Vögtle, Jörn Dengjel, Chris Meisinger, Adrian Keller, Stephan J Sigrist, Tobias Eisenberg, Frank Madeo
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 5, Pp 1-26 (2022)
Abstract Amyloid beta 42 (Abeta42) is the principal trigger of neurodegeneration during Alzheimer’s disease (AD). However, the etiology of its noxious cellular effects remains elusive. In a combinatory genetic and proteomic approach using a yeast m
Externí odkaz:
https://doaj.org/article/4c65d2eea54842d29ae6240b593bf7ff
Autor:
Klaus-Peter Dieckmann, Tomas Pokrivcak, Lajos Geczi, David Niehaus, Inken Dralle-Filiz, Cord Matthies, Tamas Dienes, Stefanie Zschäbitz, Pia Paffenholz, Tanja Gschliesser, Renate Pichler, Michal Mego, Pia Bader, Friedemann Zengerling, Julia Heinzelbecker, Philipp Krausewitz, Susanne Krege, Gaetano Aurilio, Cem Aksoy, Marcus Hentrich, Christoph Seidel, Péter Törzsök, Tim Nestler, Matthaeus Majewski, Andreas Hiester, Tomas Buchler, Sonia Vallet, Hana Studentova, Sandra Schönburg, Dora Niedersüß-Beke, Julia Ring, Emanuela Trenti, Axel Heidenreich, Christian Wülfing, Hendrik Isbarn, Uwe Pichlmeier, Martin Pichler
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 14 (2022)
Introduction: Clinical stage 1 (CS1) nonseminomatous (NS) germ cell tumors involve a 30% probability of relapse upon surveillance. Adjuvant chemotherapy with one course of bleomycin, etoposide, and cisplatin (1xBEP) can reduce this risk to pT2 was si
Externí odkaz:
https://doaj.org/article/6fb1f473ab9e4ce38bbec32affcc8d33
Autor:
Julia Ring, Patrick Rockenfeller, Claudia Abraham, Jelena Tadic, Michael Poglitsch, Katherina Schimmel, Julia Westermayer, Simon Schauer, Bettina Achleitner, Christa Schimpel, Barbara Moitzi, Gerald N. Rechberger, Stephan J. Sigrist, Didac Carmona-Gutierrez, Guido Kroemer, Sabrina Büttner, Tobias Eisenberg, Frank Madeo
Publikováno v:
Microbial Cell, Vol 4, Iss 12, Pp 411-422 (2017)
Hereditary spastic paraplegias, a group of neurodegenerative disorders, can be caused by loss-of-function mutations in the protein spartin. However, the physiological role of spartin remains largely elusive. Here we show that heterologous expression
Externí odkaz:
https://doaj.org/article/345f31f335df4374b65be0f350fe5c1c
Autor:
Ann De Vos, Tine Bynens, Joëlle Rosseels, Catherina Coun, Julia Ring, Frank Madeo, Marie-Christine Galas, Joris Winderickx, Vanessa Franssens
Publikováno v:
AIMS Molecular Science, Vol 2, Iss 2, Pp 144-160 (2015)
Since hyperphosphorylation of protein tau is a crucial event in Alzheimer’s disease, additional mechanisms besides the interplay of kinase and phosphatase activities are investigated, such as the effect of the peptidyl prolyl cis/trans isomerase Pi
Externí odkaz:
https://doaj.org/article/c8a76f21c85a42998ca66af75fafd9c6
Publikováno v:
Journal of Medicinal Chemistry. 65:10588-10610
Publikováno v:
Uro-News. 26:12-17
Autor:
Horst, Prescher, Astrid, Schweizer, Martin, Frank, Elena, Kuhfeldt, Julia, Ring, Lars, Nitschke
Publikováno v:
Journal of medicinal chemistry. 65(15)
Significant interest in the development of high-affinity ligands for Siglecs exists due to the various therapeutically relevant functions of these proteins. Here, we report a new strategy to develop and design Siglec ligands as disialyl-oligosacchari
Autor:
Claudia Abraham, Bettina Achleitner, Julia Westermayer, Gerald N. Rechberger, Jelena Tadic, Barbara Moitzi, Stephan J. Sigrist, Tobias Eisenberg, Christa Schimpel, Sabrina Büttner, Simon Schauer, Didac Carmona-Gutierrez, Katherina Schimmel, Frank Madeo, Patrick Rockenfeller, Michael Poglitsch, Julia Ring, Guido Kroemer
Publikováno v:
Microbial Cell
Microbial Cell, Vol 4, Iss 12, Pp 411-422 (2017)
Microbial Cell, Vol 4, Iss 12, Pp 411-422 (2017)
Hereditary spastic paraplegias, a group of neurodegenerative disorders, can be caused by loss-of-function mutations in the protein spartin. However, the physiological role of spartin remains largely elusive. Here we show that heterologous expression
Autor:
Berenice Fischer, Tanja Kübelbeck, Antonia Kolb, Julia Ringen, Ari Waisman, Miriam Wittmann, Susanne Karbach, Stephan Marcus Kölsch, Daniela Kramer
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Plaque psoriasis is an autoinflammatory and autoimmune skin disease, affecting 1-3% of the population worldwide. Previously, high levels of IL-36 family cytokines were found in psoriatic skin lesions, thereby contributing to keratinocyte hyperprolife
Externí odkaz:
https://doaj.org/article/c09af3e842354597b44bb3049b851775