Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Julia Rautschek"'
Autor:
Slavica Janevska, Iuliia Ferling, Katarina Jojić, Julia Rautschek, Sandra Hoefgen, Robert H. Proctor, Falk Hillmann, Vito Valiante
Publikováno v:
mBio, Vol 11, Iss 3 (2020)
ABSTRACT Fumonisin (FB) mycotoxins produced by species of the genus Fusarium detrimentally affect human and animal health upon consumption, due to the inhibition of ceramide synthase. In the present work, we set out to identify mechanisms of self-pro
Externí odkaz:
https://doaj.org/article/b07819250cac40d8bbc977bfb407b14c
Autor:
Alexander U. Bissell, Julia Rautschek, Sandra Hoefgen, Luka Raguž, Derek J. Mattern, Nauman Saeed, Slavica Janevska, Katarina Jojić, Ying Huang, Johann E. Kufs, Barbara Herboeck, Huijuan Guo, Falk Hillmann, Christine Beemelmanns, Vito Valiante
Publikováno v:
ACS Chem Biol
Sphingofungins belong to a group of structurally related sphingolipid inhibitors produced by fungi, which specifically inhibit serine palmitoyl transferases, enzymes catalyzing the initial step during sphingolipid biosynthesis. Sphingolipids are inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94e19c2f19eac7bad1e98affc3aca96a
https://doi.org/10.1021/acschembio.1c00839
https://doi.org/10.1021/acschembio.1c00839
Autor:
Christin Reimer, Johann E. Kufs, Julia Rautschek, Lars Regestein, Vito Valiante, Falk Hillmann
Publikováno v:
Nature Biotechnology. 40:751-758
Aromatic polyketides are natural polyphenolic compounds with a broad spectrum of pharmacological activities. Production of those metabolites in the model organisms Escherichia coli and Saccharomyces cerevisiae has been limited by the extensive cellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0b1cf1bbcc9d70d3d1016f825ef2cce
https://doi.org/10.1038/s41587-021-01143-8
https://doi.org/10.1038/s41587-021-01143-8
Autor:
Markus Günther, Christin Reimer, Rosa Herbst, Johann E. Kufs, Julia Rautschek, Nico Ueberschaar, Shuaibing Zhang, Gundela Peschel, Lisa Reimer, Lars Regestein, Vito Valiante, Falk Hillmann, Pierre Stallforth
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Low-molecular-weight natural products from microbes are indispensable in the development of potent drugs. However, their biological roles within an ecological context often remain elusive. Here, we shed light on natural products from eukaryotic micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5890e5b53d770eca49eb00e0a4843dfb
https://doi.org/10.1073/pnas.2116122119
https://doi.org/10.1073/pnas.2116122119
Autor:
Vito Valiante, Sandra Hoefgen, Daniel F.O. Braga, Miriam A. Rosenbaum, Johann E Kufs, Julia Rautschek, Julian Thiele, Alexander U Bissell, Lars Regestein, Jonas Fiedler, Carola Graf
Publikováno v:
ACS synthetic biology. 9(7)
Combinatorial biosynthesis has great potential for designing synthetic circuits and amplifying the production of new active compounds. Studies on multienzyme cascades are extremely useful for improving our knowledge on enzymatic catalysis. In particu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07e3db721096b8fd98dc524b5fee1ee8
https://pubmed.ncbi.nlm.nih.gov/32525654
https://pubmed.ncbi.nlm.nih.gov/32525654
Autor:
Robert H. Proctor, Falk Hillmann, Katarina Jojić, Slavica Janevska, Vito Valiante, Julia Rautschek, Iuliia Ferling, Sandra Hoefgen
Publikováno v:
mBio, Vol 11, Iss 3, p e00455-20 (2020)
mBio, Vol 11, Iss 3 (2020)
mBio, Vol 11, Iss 3 (2020)
Fumonisin (FB) mycotoxins produced by species of the genus Fusarium detrimentally affect human and animal health upon consumption, due to the inhibition of ceramide synthase. In the present work, we set out to identify mechanisms of self-protection e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f7e35571e056a03415d2c7c60607431
https://doaj.org/article/ad4f54885cd841adabc62f7f213e65f3
https://doaj.org/article/ad4f54885cd841adabc62f7f213e65f3
Publikováno v:
Organic Letters. 20:832-835
Desymmetrization of a p-quinone monoacetal by organocatalytic sulfa-Michael addition provided rapid access to a C-ring building block for a formal synthesis of (-)-codeine. By means of a diastereoselective 1,2-addition for A/C-ring union, an intramol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::576d7f7c23035be5ec1dae61d536599b
https://doi.org/10.1021/acs.orglett.7b03972
https://doi.org/10.1021/acs.orglett.7b03972