Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Julia R. Zebol"'
Autor:
Craig T. Wallington-Beddoe, Melissa R. Pitman, Melissa K. Bennett, Andrew C.W. Zannettino, Paul A.B. Moretti, Julia R. Zebol, Duncan R. Hewett, Kate Vandyke, Stuart M. Pitson, Lorena T. Davies
Publikováno v:
Oncotarget
// Craig T. Wallington-Beddoe 1,2,3 , Melissa K. Bennett 1,2,3 , Kate Vandyke 2,3,4 , Lorena Davies 1,2 , Julia R. Zebol 1,2 , Paul A.B. Moretti 1,2 , Melissa R. Pitman 1,2 , Duncan R. Hewett 3,4 , Andrew C.W. Zannettino 1,2,3,4,* and Stuart M. Pitso
Autor:
Alexander C. Lewis, Paul A.B. Moretti, Melissa R. Pitman, Stuart M. Pitson, Jason A. Powell, Maurizio Costabile, Julia R. Zebol, Lorena T. Davies, Laura F. Dagley, Andrew I. Webb, Heidi A. Neubauer
Publikováno v:
The Biochemical journal. 476(21)
Sphingosine kinase 1 (SK1) is a signalling enzyme that catalyses the phosphorylation of sphingosine to generate the bioactive lipid sphingosine 1-phosphate (S1P). A number of SK1 inhibitors and chemotherapeutics can induce the degradation of SK1, wit
Autor:
Cassandra Stefanidis, Claudine S. Bonder, Briony L. Gliddon, Maurizio Costabile, Melinda N. Tea, Melissa R. Pitman, Julia R. Zebol, Paul A.B. Moretti, Heidi A. Neubauer, Brett W. Stringer, Bryan W. Day, Stuart M. Pitson, Jason A. Powell, Jasreen Kular, Michael S. Samuel
Publikováno v:
Oncogene
While the two mammalian sphingosine kinases, SK1 and SK2, both catalyze the generation of pro-survival sphingosine 1-phosphate (S1P), their roles vary dependent on their different subcellular localization. SK1 is generally found in the cytoplasm or a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f1bf6cabe74c5c92b2081d06f30713
https://hdl.handle.net/11541.2/134345
https://hdl.handle.net/11541.2/134345
Autor:
Melissa R. Pitman, Claudine S. Bonder, Michael S. Samuel, Heidi A. Neubauer, Darren J. Creek, Paul A.B. Moretti, Briony L. Gliddon, Stuart M. Pitson, Jason A. Powell, Huasheng Chan, Tamara M. Leclercq, Julia R. Zebol, Duyen H. Pham, Amanda L. Peterson
Publikováno v:
Oncotarget
// Heidi A. Neubauer 1,2 , Duyen H. Pham 1,2 , Julia R. Zebol 1 , Paul A.B. Moretti 1 , Amanda L. Peterson 4 , Tamara M. Leclercq 1 , Huasheng Chan 1,2 , Jason A. Powell 1,3 , Melissa R. Pitman 1 , Michael S. Samuel 1,3 , Claudine S. Bonder 1,2,3 , D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b7a985d761337c790b118b5e2e1a8b1
https://hdl.handle.net/11541.2/123313
https://hdl.handle.net/11541.2/123313
Autor:
Gabor Tigyi, Claudine S. Bonder, Paul A.B. Moretti, Michaelia P. Cockshell, Katie Tooley, Briony L. Gliddon, Stuart M. Pitson, Julia R. Zebol, Lachlan M. Moldenhauer, Kate A. Parham, Wai Y. Sun
Sphingosine 1-phosphate (S1P) is a bioactive lipid that can function both extracellularly and intracellularly to mediate a variety of cellular processes. Using lipid affinity matrices and a radiolabeled lipid binding assay, we reveal that S1P directl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5e1b612f2e1110381ed26d80de40899
https://hdl.handle.net/11541.2/111922
https://hdl.handle.net/11541.2/111922
Autor:
Binks W. Wattenberg, Paul A.B. Moretti, Mathew A. Vadas, Pu Xia, Helen E. Lynn, Stuart M. Pitson, Julia R. Zebol, Tamara M. Leclercq
Publikováno v:
The Journal of Experimental Medicine
Sphingosine kinase (SK) 1 catalyzes the formation of the bioactive lipid sphingosine 1-phosphate, and has been implicated in several biological processes in mammalian cells, including enhanced proliferation, inhibition of apoptosis, and oncogenesis.
Autor:
Helen E. Lynn, Pu Xia, Julia R. Zebol, Paul A.B. Moretti, Stuart M. Pitson, Mathew A. Vadas, Binks W. Wattenberg
Publikováno v:
The EMBO Journal. 22:5491-5500
Sphingosine kinase 1 is an agonist-activated signalling enzyme that catalyses the formation of sphingosine 1-phosphate, a lipid second messenger that has been implicated in a number of agonist-driven cellular responses, including stimulation of cell
Autor:
Reza Zareie, Paul A.B. Moretti, Richard J D'Andrea, Andrew L. Darrow, Mathew A. Vadas, Stuart M. Pitson, Julia R. Zebol, Binks W. Wattenberg, Christopher J. Bagley, Claudia K. Derian, Jenson Qi
Publikováno v:
Journal of Biological Chemistry. 277:49545-49553
Sphingosine kinase catalyzes the formation of sphingosine 1-phosphate, a lipid second messenger that has been implicated in a number of agonist-driven cellular responses including mitogenesis, anti-apoptosis, and expression of inflammatory molecules.
Autor:
Stuart M. Pitson, Pu Xia, Mathew A. Vadas, Richard J D'Andrea, Paul A.B. Moretti, Binks W. Wattenberg, Julia R. Zebol, Jennifer R. Gamble
Publikováno v:
Journal of Biological Chemistry. 275:33945-33950
Sphingosine kinase (SK) catalyzes the formation of sphingosine 1-phosphate (S1P), a lipid messenger that plays an important role in a variety of mammalian cell processes, including inhibition of apoptosis and stimulation of cell proliferation. Basal
Autor:
Julie K. Calvert, Jennifer N. Clarke, Jillian M. Carr, Stuart M. Pitson, T. Kua, Michael R. Beard, Julia R. Zebol
This item is under embargo for a period of 12 months from the date of publication, in accordance with the publisher's policy.
Sphingosine kinase 1 (SphK1) is a lipid kinase with important roles including regulation of cell survival. We have prev
Sphingosine kinase 1 (SphK1) is a lipid kinase with important roles including regulation of cell survival. We have prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d07e6bf6ff044ed3a4ac84c3078a8d96
https://hdl.handle.net/1959.8/153046
https://hdl.handle.net/1959.8/153046