Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Julia R. Palmucci"'
Autor:
Julia R. Palmucci, Blake E. Sells, Charles D. Giamberardino, Dena L. Toffaletti, Baodi Dai, Yohannes G. Asfaw, Laura G. Dubois, Zhong Li, Barbara Theriot, Wiley A. Schell, William Hope, Jennifer L. Tenor, John R. Perfect
Publikováno v:
mBio, Vol 15, Iss 5 (2024)
ABSTRACTInvasive fungal infections are a significant public health concern, with mortality rates ranging from 20% to 85% despite current treatments. Therefore, we examined whether a ketogenic diet could serve as a successful treatment intervention in
Externí odkaz:
https://doaj.org/article/1c4d26c9463d44078161728fc5c59925
Autor:
Poppy Sephton-Clark, Jennifer L. Tenor, Dena L. Toffaletti, Nancy Meyers, Charles Giamberardino, Síle F. Molloy, Julia R. Palmucci, Adrienne Chan, Tarsizio Chikaonda, Robert Heyderman, Mina Hosseinipour, Newton Kalata, Cecilia Kanyama, Christopher Kukacha, Duncan Lupiya, Henry C. Mwandumba, Thomas Harrison, Tihana Bicanic, John R. Perfect, Christina A. Cuomo
Publikováno v:
mBio, Vol 13, Iss 6 (2022)
ABSTRACT Cryptococcus neoformans is the causative agent of cryptococcosis, a disease with poor patient outcomes that accounts for approximately 180,000 deaths each year. Patient outcomes may be impacted by the underlying genetics of the infecting iso
Externí odkaz:
https://doaj.org/article/2422d58ac858444989d662505ee09ad6
Autor:
Charles D. Giamberardino, Wiley A. Schell, Jennifer L. Tenor, Dena L. Toffaletti, Julia R. Palmucci, Choiselle Marius, Jane-Valeriane K. Boua, Quinlyn Soltow, Robert Mansbach, M. Arthur Moseley, J. Will Thompson, Laura G. Dubois, William Hope, John R. Perfect, Karen Joy Shaw
Publikováno v:
mBio, Vol 13, Iss 6 (2022)
ABSTRACT Cryptococcal Meningitis (CM) is uniformly fatal if not treated, and treatment options are limited. We previously reported on the activity of APX2096, the prodrug of the novel Gwt1 inhibitor APX2039, in a mouse model of CM. Here, we investiga
Externí odkaz:
https://doaj.org/article/12c94fc2bb48423287573f9192ce65ce
Autor:
Charles D Giamberardino, Jennifer L Tenor, Dena Toffaletti, Julia R Palmucci, Don Cilla, William Hope, John R Perfect
Publikováno v:
Open Forum Infectious Diseases. 9
Background Cryptococcal meningitis (CM) is a fungal disease with significant global morbidity and mortality. There are multiple new therapies being developed to improve the current regimens involving amphotericin B, flucytosine, and fluconazole. ATI-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6205318d21ba5d74a796be2a536e51f4
https://doi.org/10.1093/ofid/ofac492.657
https://doi.org/10.1093/ofid/ofac492.657
Autor:
John R. Perfect, Jennifer L. Tenor, Quinlyn A. Soltow, Jane-Valeriane Boua, Julia R Palmucci, Dena L. Toffaletti, Karen J Shaw, Charles Giamberardino, Choiselle Marius
Publikováno v:
Open Forum Infectious Diseases
Background Cryptococcal meningitis (CM), caused primarily by Cryptococcus neoformans, is uniformly fatal if not treated. Treatment options are limited especially in resource-poor geographical regions, and mortality rates remain high despite current t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8ff8a9261f2cec6838274185271281c
https://doi.org/10.1093/ofid/ofaa439.478
https://doi.org/10.1093/ofid/ofaa439.478
Publikováno v:
Environmental science and pollution research international. 25(11)
Antifouling chemicals have a long history of causing toxicity to aquatic organisms. We measured growth and developmental timing in wood frog tadpoles exposed to the antifouling chemical medetomidine (10 nM–10 μM) starting at two different developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85580754403ed4921186d184c7a68cf9
https://pubmed.ncbi.nlm.nih.gov/29388154
https://pubmed.ncbi.nlm.nih.gov/29388154
Exposure to SSRI-type antidepressants increases righting time in the marine snail Ilyanassa obsoleta
Autor:
Elizabeth E. Donovan, Peter P. Fong, Stephanie K. Adamczak, Olivia J. Lambert, Taylor B. Bury, Julia R. Palmucci
Publikováno v:
Environmental science and pollution research international. 24(1)
Exposure to human antidepressants has been shown to disrupt locomotion and other foot-mediated mechanisms in aquatic snails. We tested the effect of three selective serotonin reuptake inhibitor (SSRI)- and one selective serotonin-norepinephrine reupt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d15e71612941d9e040627b59c31b10ad
https://pubmed.ncbi.nlm.nih.gov/27752949
https://pubmed.ncbi.nlm.nih.gov/27752949
Publikováno v:
PLoS Pathogens, Vol 19, Iss 12, p e1011845 (2023)
Externí odkaz:
https://doaj.org/article/e5620e1a996a472f999cf6a72a0cdb0e