Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Julia Proff"'
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-12 (2018)
Abstract Background During infection with human cytomegalovirus (HCMV) several viral proteins occur on cell surfaces in high quantity. We thus pursue an HLA-independent approach for immunotherapy of HCMV using chimeric antigen receptors (CARs) and bi
Externí odkaz:
https://doaj.org/article/3e8413de087e454d811b609b4ef93361
Autor:
Manfred Lehner, Gabriel Götz, Julia Proff, Niels Schaft, Jan Dörrie, Florian Full, Armin Ensser, Yves A Muller, Adelheid Cerwenka, Hinrich Abken, Ornella Parolini, Peter F Ambros, Heinrich Kovar, Wolfgang Holter
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31210 (2012)
We explored the possibility to target Ewing's sarcoma family of tumors (ESFT) by redirecting T cells. To this aim, we considered NKG2D-ligands (NKG2D-Ls) as possible target antigens. Detailed analysis of the expression of MICA, MICB, ULBP-1, -2, and
Externí odkaz:
https://doaj.org/article/fe1b7ffa73194d2fa23042d04da80b5d
Autor:
Janett Schwarz, Julia Proff, Anika Hävemeier, Markus Ladwein, Klemens Rottner, Britta Barlag, Andreas Pich, Helma Tatge, Ingo Just, Ralf Gerhard
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44358 (2012)
The Rho GTPases Rac1 and Cdc42 regulate a variety of cellular functions by signaling to different signal pathways. It is believed that the presence of a specific effector at the location of GTPase activation determines the route of downstream signali
Externí odkaz:
https://doaj.org/article/5e44924797cc488a8fbeaeddd3ecf374
Autor:
Jochen Pendzialek, Markus Münz, Armin Ensser, Charlotte U. Brey, Julia Proff, Manfred Lehner, Johannes Brozy, Wolfgang Holter, Benjamin Salzer, Natascha Teufert
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Bispecific T cell engager (BiTE) antibody constructs are successfully used as cancer therapeutics. We hypothesized that this treatment strategy could also be applicable for therapy of human cytomegalovirus (HCMV) infection, since HCMV-encoded protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c225ba3f33e034b7dcbb12afe03d2b3
http://europepmc.org/articles/PMC6261951
http://europepmc.org/articles/PMC6261951
Autor:
Christian Walterskirchen, Florian Full, Julia Proff, Armin Ensser, Manfred Lehner, René Geyeregger, Wolfgang Holter, Charlotte U. Brey
Publikováno v:
Frontiers in Microbiology
In order to explore the potential of HLA-independent T cell therapy for human cytomegalovirus (HCMV) infections, we developed a chimeric antigen receptor (CAR) directed against the HCMV encoded glycoprotein B (gB), which is expressed at high levels o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd720a972665e1f732717968b1daa850
Autor:
Julia Proff, Jan Dörrie, Manfred Lehner, Philip Diessenbacher, Martina Schmid, Armin Ensser, Martin Leverkus, Niels Schaft, Wolfgang Holter, Beate Kellert, Eckhart Kämpgen
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 188(10)
The life span of dendritic cells (DCs) is determined by the balance of pro- and antiapoptotic proteins. In this study, we report that serum-free cultured human monocyte-derived DCs after TLR stimulation with polyinosinic acid-polycytidylic acid or LP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9485d72ca0f83266a310e194044ada96
https://pubmed.ncbi.nlm.nih.gov/22504646
https://pubmed.ncbi.nlm.nih.gov/22504646
Autor:
Anika Hävemeier, Klemens Rottner, Markus Ladwein, Helma Tatge, Ralf Gerhard, Julia Proff, Ingo Just, Britta Barlag, Andreas Pich, Janett Schwarz
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44358 (2012)
PLoS ONE
PLoS ONE
The Rho GTPases Rac1 and Cdc42 regulate a variety of cellular functions by signaling to different signal pathways. It is believed that the presence of a specific effector at the location of GTPase activation determines the route of downstream signali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ddfc1701878aa8818a483ccdacfe449
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22970203/pdf/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22970203/pdf/?tool=EBI