Agrochelin, a New Cytotoxic Antibiotic from a Marine Agrobacterium Taxonomy, Fermentation, Isolation, Physico-chemical Properties and Biological Activity

Autor: Librada M. Cañedo, José L. Fernández Puentes, M. Dolores Garcia Gravalos, C. Acebal, Fernando de la Calle, Francisco Romero, Julia Perez Baz, Pilar Rodríguez

Publikováno v: The Journal of Antibiotics. 52:983-987

Agrochelin, a new alkaloid cytotoxic substance, was produced by the fermentation of Agrobacterium sp. The compound was obtained from the bacterial cells by solvent extraction and purified by silica gel chromatography. Agrochelin (1) and its acetyl de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dc676fd8849fe779acc67919d84be1c
https://doi.org/10.7164/antibiotics.52.983

Synthesis and Aldol Stereoselectivity of 2-Oxazolidinones Derived from L-Histidine

Autor: Francisco Bermejo Gonzalez, Julia Perez Baz, Fernando Mayor Real, Fabio Santinelli

Publikováno v: Scopus-Elsevier

The regiospecific synthesis of the 2-oxazolidinones 5b, 7, 12a, and 12b starting from L-histidine la is described. The stereoselectivity in the dibutyl(trifluoromethylsulfonyloxy)borane promoted aldol condensation between the chiral imides 13a and 13

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a514dbe85a1dd5221077cd573aa8d280
https://doi.org/10.1246/bcsj.64.674

Polyprenyl-hydroquinones and -furans from three marine sponges inhibit the cell cycle regulating phosphatase CDC25A

Autor: Olivier Lozach, Ilkay Erdogan-Orhan, Bilge Sener, Laurent Meijer, Salvatore De Rosa, Maryse Leost, Sergei Rakhilin, Julia Perez-Baz

Publikováno v: Natural Product Letters
Natural Product Letters, 2004, 18, pp.1-9
Natural Product Letters, Informa UK (Taylor & Francis), 2004, 18, pp.1-9
Natural product research
18 (2004): 1–9.
info:cnr-pdr/source/autori:Erdogan, B. Sener, S. De Rosa, J. Perez-Baz, O. Lozach, M. Leost, S. Rakhilin, and L. Meijer/titolo:Polyprenyl-hydroquinones and-furans from three marine sponges inhibit the cell cycle regulating phosphatase CDC25A/doi:/rivista:Natural product research (Print)/anno:2004/pagina_da:1/pagina_a:9/intervallo_pagine:1–9/volume:18

The CDC25 phosphatases regulate the cell division cycle by controlling the activity of cyclin-dependent kinases. While screening for inhibitors of phosphatases among natural products we repeatedly found that some polyprenyl-hydroquinones and polypren

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f7e758ea8b261be32808af854e45bcc
https://pubmed.ncbi.nlm.nih.gov/14974610

IB-00208, a new cytotoxic polycyclic xanthone produced by a marine-derived Actinomadura. II. Isolation, physico-chemical properties and structure determination

Autor: José L. Fernández Puentes, Librada M. Cañedo, Julia Perez Baz, Julian Castro Rodriguez

Publikováno v: The Journal of antibiotics. 56(3)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::907f617ae62d5401a104e7275699a444
https://pubmed.ncbi.nlm.nih.gov/12760690

4'-N-methyl-5'-hydroxystaurosporine and 5'-hydroxystaurosporine, new indolocarbazole alkaloids from a marine Micromonospora sp. strain

Autor: Julia Perez Baz, José L. Fernández Puentes, Dolores Garcia Gravalos, Librada M. Canedo Hernandez, Jesus Angel de la Fuente Blanco, Francisco Romero Millan, Rosa Isabel Fernández-Chimeno, Fernando Espliego Vazquez

Publikováno v: The Journal of antibiotics. 53(9)

Two new indolocarbazole alkaloids, 4'-N-methyl-5'-hydroxystaurosporine (2) and 5'-hydroxystaurosporine (3), were isolated together with the known staurosporine (1) from the culture broth of a marine Micromonospora sp. (strain L-31-CLCO-002). The ferm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6dc7e66994c1a8e94a81ebf29c7d010
https://pubmed.ncbi.nlm.nih.gov/11099222