Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Julia P. Hofmann"'
Publikováno v:
mBio, Vol 7, Iss 4 (2016)
ABSTRACT Prions are infectious protein particles that replicate by templating their aggregated state onto soluble protein of the same type. Originally identified as the causative agent of transmissible spongiform encephalopathies, prions in yeast (Sa
Externí odkaz:
https://doaj.org/article/575fb5a91c9643c08b69cfb568e5e2da
Autor:
Julia Danielle Hofmann, Rebekka Biedendieck, Annika-Marisa Michel, Dietmar Schomburg, Dieter Jahn, Meina Neumann-Schaal
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0244988 (2021)
The virulence of Clostridioides difficile (formerly Clostridium difficile) is mainly caused by its two toxins A and B. Their formation is significantly regulated by metabolic processes. Here we investigated the influence of various sugars (glucose, f
Externí odkaz:
https://doaj.org/article/325b50d31f1c439bb7884b4cf0b231d0
Autor:
Julia D. Hofmann, Andreas Otto, Mareike Berges, Rebekka Biedendieck, Annika-Marisa Michel, Dörte Becher, Dieter Jahn, Meina Neumann-Schaal
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
The obligate anaerobe, spore forming bacterium Clostridioides difficile (formerly Clostridium difficile) causes nosocomial and community acquired diarrhea often associated with antibiotic therapy. Major virulence factors of the bacterium are the two
Externí odkaz:
https://doaj.org/article/d92d6334a7f84191858ee909c559e123
Autor:
Matthias Steglich, Julia D. Hofmann, Julia Helmecke, Johannes Sikorski, Cathrin Spröer, Thomas Riedel, Boyke Bunk, Jörg Overmann, Meina Neumann-Schaal, Ulrich Nübel
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
We report the frequent, convergent loss of two genes encoding the substrate-binding protein and the ATP-binding protein of an ATP-binding cassette (ABC) transporter from the genomes of unrelated Clostridioides difficile strains. This specific genomic
Externí odkaz:
https://doaj.org/article/45e821eb9b6d470dbe615f99fd147feb
Autor:
Julia P. Hofmann, Paolo Salomoni
Publikováno v:
The Functional Nucleus ISBN: 9783319388809
Acute promyelocytic leukaemia is a myeloid neoplasm characterized by expansion of promyelocytic progenitors. Its main driver is the oncogenic fusion protein generated by the (t15;17) chromosomal translocation between the promyelocytic leukaemia (PML)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67b181461e61ad129b52496e8d941f36
https://doi.org/10.1007/978-3-319-38882-3_4
https://doi.org/10.1007/978-3-319-38882-3_4
Autor:
Isabel Marquardt, Josefine Jakob, Jessica Scheibel, Julia Danielle Hofmann, Frank Klawonn, Meina Neumann-Schaal, Ralf Gerhard, Dunja Bruder, Lothar Jänsch
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Clostridioides difficile is the major cause of antibiotic-associated colitis (CDAC) with increasing prevalence in morbidity and mortality. Severity of CDAC has been attributed to hypervirulent C. difficile strains, which in addition to toxin A and B
Externí odkaz:
https://doaj.org/article/2f8368248e8d4b778868278f1dc5bb4b
Autor:
Isabel Bernal, Julia Danielle Hofmann, Björn Bulitta, Frank Klawonn, Annika-Marisa Michel, Dieter Jahn, Meina Neumann-Schaal, Dunja Bruder, Lothar Jänsch
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Clostridioides difficile infection (CDI) causes severe inflammatory responses at the intestinal mucosa but the immunological mechanisms underlying CDI-related immunopathology are still incompletely characterized. Here we identified for the first time
Externí odkaz:
https://doaj.org/article/67026cbe2f3946edbe6059086ca8b462