The first myriapod genome sequence reveals conservative arthropod gene content and genome organisation in the centipede Strigamia maritima.

Autor: Ariel D Chipman, David E K Ferrier, Carlo Brena, Jiaxin Qu, Daniel S T Hughes, Reinhard Schröder, Montserrat Torres-Oliva, Nadia Znassi, Huaiyang Jiang, Francisca C Almeida, Claudio R Alonso, Zivkos Apostolou, Peshtewani Aqrawi, Wallace Arthur, Jennifer C J Barna, Kerstin P Blankenburg, Daniela Brites, Salvador Capella-Gutiérrez, Marcus Coyle, Peter K Dearden, Louis Du Pasquier, Elizabeth J Duncan, Dieter Ebert, Cornelius Eibner, Galina Erikson, Peter D Evans, Cassandra G Extavour, Liezl Francisco, Toni Gabaldón, William J Gillis, Elizabeth A Goodwin-Horn, Jack E Green, Sam Griffiths-Jones, Cornelis J P Grimmelikhuijzen, Sai Gubbala, Roderic Guigó, Yi Han, Frank Hauser, Paul Havlak, Luke Hayden, Sophie Helbing, Michael Holder, Jerome H L Hui, Julia P Hunn, Vera S Hunnekuhl, LaRonda Jackson, Mehwish Javaid, Shalini N Jhangiani, Francis M Jiggins, Tamsin E Jones, Tobias S Kaiser, Divya Kalra, Nathan J Kenny, Viktoriya Korchina, Christie L Kovar, F Bernhard Kraus, François Lapraz, Sandra L Lee, Jie Lv, Christigale Mandapat, Gerard Manning, Marco Mariotti, Robert Mata, Tittu Mathew, Tobias Neumann, Irene Newsham, Dinh N Ngo, Maria Ninova, Geoffrey Okwuonu, Fiona Ongeri, William J Palmer, Shobha Patil, Pedro Patraquim, Christopher Pham, Ling-Ling Pu, Nicholas H Putman, Catherine Rabouille, Olivia Mendivil Ramos, Adelaide C Rhodes, Helen E Robertson, Hugh M Robertson, Matthew Ronshaugen, Julio Rozas, Nehad Saada, Alejandro Sánchez-Gracia, Steven E Scherer, Andrew M Schurko, Kenneth W Siggens, DeNard Simmons, Anna Stief, Eckart Stolle, Maximilian J Telford, Kristin Tessmar-Raible, Rebecca Thornton, Maurijn van der Zee, Arndt von Haeseler, James M Williams, Judith H Willis, Yuanqing Wu, Xiaoyan Zou, Daniel Lawson, Donna M Muzny, Kim C Worley, Richard A Gibbs, Michael Akam, Stephen Richards

Publikováno v: PLoS Biology, Vol 12, Iss 11, p e1002005 (2014)

Myriapods (e.g., centipedes and millipedes) display a simple homonomous body plan relative to other arthropods. All members of the class are terrestrial, but they attained terrestriality independently of insects. Myriapoda is the only arthropod class

Externí odkaz: https://doaj.org/article/e3791b30489f4c739cd076841b2b4030

The mouse resistance protein Irgm1 (LRG-47): a regulator or an effector of pathogen defense?

Autor: Julia P Hunn, Jonathan C Howard

Publikováno v: PLoS Pathogens, Vol 6, Iss 7, p e1001008 (2010)

Externí odkaz: https://doaj.org/article/a6d9350f16ed4166a51b80894228a0b5

The immunity-related GTPases in mammals: a fast-evolving cell-autonomous resistance system against intracellular pathogens

Autor: Alan Sher, Jonathan C. Howard, Julia P. Hunn, Carl G. Feng

Publikováno v: Mammalian Genome. 22:43-54

The immunity-related GTPases (IRGs) belong to the family of large, interferon-inducible GTPases and constitute a cell-autonomous resistance system essential for the control of vacuolar pathogens like Toxoplasma gondii in mice. Recent results demonstr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5960e7cfe2a52997ab3be88b9adc28f4
https://doi.org/10.1007/s00335-010-9293-3

Balance of Irgm protein activities determines IFN-γ-induced host defense

Autor: Jörn Coers, David N. Howell, Maanasa Indaram, Julia P. Hunn, Gregory A. Taylor, Ashley R. Burroughs, Jonathan C. Howard, Xiaoju Daniell, Michael N. Starnbach, Stanley C. Henry, Alan Sher, Carl G. Feng

Publikováno v: Journal of Leukocyte Biology. 85:877-885

The immunity-related GTPases (IRG), also known as p47 GTPases, are a family of proteins that are tightly regulated by IFNs at the transcriptional level and serve as key mediators of IFN-regulated resistance to intracellular bacteria and protozoa. Amo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d780c239973635db1d41f1f7ddf397a
https://doi.org/10.1189/jlb.1008599

The IRG protein-based resistance mechanism in mice and its relation to virulence in Toxoplasma gondii

Autor: Julia P. Hunn, Tobias Steinfeldt, Jonathan C. Howard

Publikováno v: Current opinion in microbiology. 14(4)

IRG proteins (immunity-related GTPases) provide an early defense mechanism in mice against the protozoal pathogen, Toxoplasma gondii. This is a particularly suitable time to provide a brief review of this host–pathogen interaction because the natur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71118b76bf4e58b939586a32ca03cfad
https://pubmed.ncbi.nlm.nih.gov/21783405