Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Julia Olah"'
Autor:
Roberta Coroniti, Sándor Lovas, Julia Olah, Daniel Knappe, Laszlo Otvos, Friederike I. Nollmann, John D. Wade, Eva Surmacz, Ralf Hoffmann, Ilona Kovalszky
Publikováno v:
Peptide Science. 104:156-166
Adiponectin, an adipose tissue-excreted adipokine plays protective roles in metabolic and cardiovascular diseases and exerts anti-cancer activities, partially by interfering with leptin-induced signaling. Previously we identified the active site in t
Autor:
Laura Scolaro, Ralf Hoffmann, Eva Surmacz, Gabriella Beko, Suode Zhang, Andras Sztodola, Julia Olah, John D. Wade, Ilona Kovalszky, Laszlo Otvos, Marco Cassone, Marcus P. D. Hatfield, Sándor Lovas, Daniel Knappe
Publikováno v:
Biopolymers. 96:117-125
Leptin, a multifunctional hormone, controls various processes in both the central nervous system and in peripheral tissues. Because of the presence of multiple leptin/receptor (ObR) interaction sites and diverse leptin activities, the literature lack
Leptin-based glycopeptide induces weight loss and simultaneously restores fertility in animal models
Autor:
Andras Sztodola, Rita Ferla, Laszlo Otvos, Sándor Lovas, Julia Olah, Ilona Kovalszky, Laura Scolaro, Marcus P. D. Hatfield, Marco Cassone, Eva Surmacz
Publikováno v:
Diabetes, Obesity and Metabolism. 12:393-402
Aim: To design, manufacture and test a second generation leptin receptor (ObR) agonist glycopeptide derivative. The major drawback to current experimental therapies involving leptin protein is the appearance of treatment resistance. Our novel peptido
Autor:
Alexandra Fullár, Ágnes Márk, Zoltán Hujber, Károly Vékey, Anna Sebestyén, András Jeney, Norbert Szoboszlai, Cs. Kriston, E. Pap, Ilona Kovalszky, Julia Olah, Judit Kralovánszky
Publikováno v:
Cancer Cell International
Europe PubMed Central
Europe PubMed Central
Background Alterations in cellular metabolism are considered as hallmarks of cancers, however, to recognize these alterations and understand their mechanisms appropriate techniques are required. Our hypothesis was to determine whether dominant bioene
Autor:
Julia Olah, Roma Stawikowska, Tim D. Hewitson, Maciej Stawikowski, Ralf Hoffmann, Feng Lin, Ilona Kovalszky, Predrag Cudic, John D. Wade, Laszlo Otvos, Daniel Knappe, Sándor Lovas, Eva Surmacz
Publikováno v:
Frontiers in Chemistry, Vol 2 (2014)
Frontiers in Chemistry
Frontiers in Chemistry
The adipose tissue participates in the regulation of energy homeostasis as an important endocrine organ that secretes a number of biologically active adipokines, including adiponectin. Recently we developed and characterized a first-in-class peptide-
Autor:
András Jeney, Ferenc Timár, Sándor Paku, Jozsef Bocsi, Gábor Pogány, Julia Olah, Gábor Polony, Gordon W. Laurie, Revekka Harisi
Publikováno v:
Oncology. 60:274-281
Objectives and Methods: Tumor dormancy and resistance to cytotoxic agents are key limiting events in the treatment of malignant diseases. To determine whether both are influenced by the extracellular milieu in which tumors reside, HT1080 human fibros
Autor:
Laszlo Otvos, Ilona Kovalszky, Annamaria Molino, Q. Piubello, John D. Wade, Rita Ferla, Kaushik Nama, Andras Sztodola, Mirko Riolfi, Eva Surmacz, Julia Olah
Publikováno v:
European journal of cancer (Oxford, England : 1990). 47(10)
Triple-negative breast cancers, which represent 10-20% of all mammary tumours, are characterised by the aggressive phenotype, are often found in younger women and have been associated with poor prognosis. Obesity increases the risk for triple-negativ
Autor:
Ferenc Timár, Jozsef Dudas, Revekka Harisi, Miklós Szendröi, András Jeney, Gábor Pogány, Julia Olah
Publikováno v:
Cancer chemotherapy and pharmacology. 58(3)
Purpose: To elucidate the role of extracellular matrix (ECM) in repopulation capacity of osteosarcoma cells after doxorubicin treatment. Methods: OSCORT cells established in our laboratory from a human osteosarcoma, were treated with doxorubicin in m
Publikováno v:
European journal of gastroenterologyhepatology. 16(2)
Transforming growth factor beta-1 (TGF-beta 1) is thought to be one of the most important factors affecting the development of fibrotic processes in the liver.To discover whether endogenously higher TGF-beta 1 production influences the progression an
Autor:
Attila Zalatnai, Ferenc Timár, Julia Olah, Zs. Schaff, András Jeney, Karoly Lapis, Béla Szende, A. Divald, Ilona Kovalszky
Publikováno v:
Biochemical Pharmacology as an Approach to Gastrointestinal Disorders ISBN: 9789401062671
The elucidation of the pathobiological events in chronic liver diseases — such as cellular injury, cell proliferation, remodelling of extracellular matrix — has considerable importance for establishing the rational bases of hepatopharmacology. To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28b61e58ba47c1d2b41131f88cc7b17d
https://doi.org/10.1007/978-94-011-5390-4_29
https://doi.org/10.1007/978-94-011-5390-4_29