Effect of Chronic Valproic Acid Treatment on Hepatic Gene Expression Profile in Wfs1 Knockout Mouse

Autor: Marite Punapart, Mall Eltermaa, Julia Oflijan, Silva Sütt, Anne Must, Sulev Kõks, Leonard C. Schalkwyk, Catherine Fernandes, Eero Vasar, Ursel Soomets, Anton Terasmaa

Publikováno v: PPAR Research, Vol 2014 (2014)

Valproic acid (VPA) is a widely used anticonvulsant and mood-stabilizing drug whose use is often associated with drug-induced weight gain. Treatment with VPA has been shown to upregulate Wfs1 expression in vitro. Aim of the present study was to compa

Externí odkaz: https://doaj.org/article/a2cfd09662a04d48ad3bb711a9e2b95e

Dynamic modulation of FGFR1–5-HT1A heteroreceptor complexes. Agonist treatment enhances participation of FGFR1 and 5-HT1A homodimers and recruitment of β-arrestin2

Autor: Julia Oflijan, Miklós Palkovits, Kjell Fuxe, Manuel Narváez, Luigi F. Agnati, Fidel Corrales, Dasiel O. Borroto-Escuela

Publikováno v: Biochemical and Biophysical Research Communications. 441:387-392

New findings show that neurotrophic and antidepressant effects of 5-HT in brain can, in part, be mediated by activation of the 5-HT1A receptor protomer in the hippocampal and raphe FGFR1-5-HT1A heteroreceptor complexes enhancing the FGFR1 signaling.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c8b83ef5e5e3c4ce34f8bff1a948574
https://doi.org/10.1016/j.bbrc.2013.10.067

Evidence for the existence of dopamine D2R and Sigma 1 allosteric receptor-receptor interaction in the rat brain: role in brain plasticity and cocaine action

Autor: Kjell Fuxe, Luca Pinton, Julia Oflijan, Luigi F. Agnati, Dasiel O. Borroto-Escuela, Manuel Narváez

Publikováno v: SpringerPlus

Drug addiction is regarded as one of the most important neuropsychiatric diseases afflicting our society today. A prototypic drug of abuse is cocaine which directly acts on the brain reward system. In this work we present evidence on the existence of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b2c72705379c7c64822024013d819c3
https://doi.org/10.1186/2193-1801-4-s1-p37

P.1.b.005 On the balance and distribution of adenosine A2A homoreceptor and A1-A2A isoreceptor complexes in the hippocampus of the rat brain

Autor: Luca Pinton, D.O. Borroto Escuela, Fidel Corrales, Miles Woolfenden, Julia Oflijan, A. Jimenez-Beristein, L. F. Agnati, Ismel Brito, Manuel Narváez

Publikováno v: European Neuropsychopharmacology. 25:S180-S181

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8c6906795f33c55caa1a501c2e2a4961
https://doi.org/10.1016/s0924-977x(15)30170-x

The G protein-coupled receptor heterodimer network (GPCR-HetNet) and its hub components

Autor: Diego Guidolin, Alicia Rivera, Kamila Skieterska, Dasiel O. Borroto-Escuela, Luigi F. Agnati, Jolien Duchou, Diana Suárez-Boomgaard, Kjell Fuxe, Michael Di Palma, Ismel Brito, Julia Oflijan, Kathleen Van Craenenbroeck, Wilber Romero-Fernandez

Publikováno v: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
International Journal of Molecular Sciences
Digital.CSIC. Repositorio Institucional del CSIC
instname
International Journal of Molecular Sciences, Vol 15, Iss 5, Pp 8570-8590 (2014)
International Journal of Molecular Sciences; Volume 15; Issue 5; Pages: 8570-8590

G protein-coupled receptors (GPCRs) oligomerization has emerged as a vital characteristic of receptor structure. Substantial experimental evidence supports the existence of GPCR-GPCR interactions in a coordinated and cooperative manner. However, desp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36bda1ade27264f74b7c1e3e6fd5abea
http://hdl.handle.net/10261/132350