Accelerated pharmaceutical protein development with integrated cell free expression, purification, and bioconjugation

Autor: Dominique Richardson, Marco G. Casteleijn, Jaakko Itkonen, Arto Urtti, Julia Nievas

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Richardson, D, Itkonen, J, Nievas, J, Urtti, A & Casteleijn, M G 2018, ' Accelerated pharmaceutical protein development with integrated cell free expression, purification, and bioconjugation ', Scientific Reports, vol. 8, no. 1, 11967, pp. 2045-2322 . https://doi.org/10.1038/s41598-018-30435-4
Scientific Reports

The use of living cells for the synthesis of pharmaceutical proteins, though state-of-the-art, is hindered by its lengthy process comprising of many steps that may affect the protein’s stability and activity. We aimed to integrate protein expressio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad1433638bd3889e8f1b1aca4fc3b0b3
http://hdl.handle.net/10138/239090