Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Julia N. Danon"'
Decoupling peptide binding from T cell receptor recognition with engineered chimeric MHC-I molecules
Autor:
Georgia F. Papadaki, Omar Ani, Tyler J. Florio, Michael C. Young, Julia N. Danon, Yi Sun, Devin Dersh, Nikolaos G. Sgourakis
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Major Histocompatibility Complex class I (MHC-I) molecules display self, viral or aberrant epitopic peptides to T cell receptors (TCRs), which employ interactions between complementarity-determining regions with both peptide and MHC-I heavy chain ‘
Externí odkaz:
https://doaj.org/article/302e579d551846d78a6301c84be31c34
Autor:
Yi Sun, Michael C. Young, Claire H. Woodward, Julia N. Danon, Hau Truong, Sagar Gupta, Trenton J. Winters, George Burslem, Nikolaos G. Sgourakis
Publikováno v:
bioRxiv
The polymorphic nature and intrinsic instability of class I major histocompatibility complex (MHC-I) and MHC-like molecules loaded with suboptimal peptides, metabolites, or glycolipids presents a fundamental challenge for identifying disease-relevant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ba1efc54024f74b446f278e0b2bdf8a
https://doi.org/10.1101/2023.03.18.533266
https://doi.org/10.1101/2023.03.18.533266
Autor:
Yi Sun, Georgia F. Papadaki, Christine A. Devlin, Julia N. Danon, Michael C. Young, Trenton J. Winters, George M. Burslem, Erik Procko, Nikolaos G. Sgourakis
Publikováno v:
Science Advances. 9
Immunological chaperones tapasin and TAP binding protein, related (TAPBPR) play key roles in antigenic peptide optimization and quality control of nascent class I major histocompatibility complex (MHC-I) molecules. The polymorphic nature of MHC-I pro