Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Julia Mayer"'
Redox-dependent plasticity of oxMIF facilitates its interaction with CD74 and therapeutic antibodies
Autor:
Sara Sajko, Erin Skeens, Alexander Schinagl, Maroua Ferhat, Irina Mirkina, Julia Mayer, Gregor Rossmueller, Michael Thiele, George P. Lisi
Publikováno v:
Redox Biology, Vol 75, Iss , Pp 103264- (2024)
MIF is a ubiquitous protein involved in proinflammatory processes, which undergoes an oxidation-driven conformational change to oxidized (ox)MIF. We demonstrate that hypochlorous acid, produced by neutrophil-released myeloperoxidase (MPO) under infla
Externí odkaz:
https://doaj.org/article/c6babf44e7bb434a82ae91e78c563cd1
Publikováno v:
Applied Sciences, Vol 14, Iss 1, p 396 (2023)
Urban tree cadastres, crucial for climate adaptation and urban planning, face challenges in maintaining accuracy and completeness. A transdisciplinary approach in Kaiserslautern, Germany, complements existing incomplete tree data with additional prec
Externí odkaz:
https://doaj.org/article/5001b8d4c46a4b708b4b7dd4b3136e4c
Autor:
Philipp J. Hohensinner, Julia Mayer, Julia Kichbacher, Julia Kral-Pointner, Barbara Thaler, Christoph Kaun, Lena Hell, Patrick Haider, Marion Mussbacher, Johannes A. Schmid, Stefan Stojkovic, Svitlana Demyanets, Michael B. Fischer, Kurt Huber, Katharina Wöran, Christian Hengstenberg, Walter S. Speidl, Rudolf Oehler, Ingrid Pabinger, Johann Wojta
Publikováno v:
Haematologica, Vol 106, Iss 2 (2020)
Macrophages are versatile cells that can be polarized by the tissue environment to fulfill required needs. Proinflammatory polarization is associated with increased tissue degradation and propagation of inflammation whereas alternative polarization w
Externí odkaz:
https://doaj.org/article/c88174e20a0542a79f36b73e83873944
Publikováno v:
EAI Endorsed Transactions on Security and Safety, Vol 1, Iss 1, Pp 1-13 (2016)
The widespread adoption of social computing applications is transforming our world. It has changed the way we routinely communicate and navigate our environment and enabled political revolutions. However, despite these applications’ ability to supp
Externí odkaz:
https://doaj.org/article/a86ad54c7d3e47c1b9eca09720fe18ed
Autor:
Sylvia Gruber, Marlene Arnold, Nilsu Cini, Victoria Gernedl, Sabine Hetzendorfer, Lisa-Marie Kowald, Peter Kuess, Julia Mayer, Susanne Morava, Stephanie Pfaffinger, Andreas Rohorzka, Wolfgang Dörr
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 6, p 1684 (2018)
Oral mucositis is the most frequently occurring early side effect of head-and-neck cancer radiotherapy. Systemic dermatan sulfate (DS) treatment revealed a significant radioprotective potential in a preclinical model of oral mucositis. This study was
Externí odkaz:
https://doaj.org/article/fe19e4da626a4c209ffda15846b9823d
Autor:
Gregor Rossmueller, Irina Mirkina, Barbara Maurer, Verena Hoeld, Julia Mayer, Michael Thiele, Randolf J. Kerschbaumer, Alexander Schinagl
Publikováno v:
Molecular Cancer Therapeutics. 22:555-569
High levels of macrophage migration inhibitory factor (MIF) in patients with cancer are associated with poor prognosis. Its redox-dependent conformational isoform, termed oxidized MIF (oxMIF), is a promising tumor target due to its selective occurren
Autor:
Carlotta Julia Mayer, Julia Mahal, Katja Schmalenberger, Magdalena Wekenborg, Anna Georg, Beate Ditzen
Publikováno v:
PPmP - Psychotherapie · Psychosomatik · Medizinische Psychologie. 72:341-344
Autor:
Luciano Fratocchi, Julia Mayer
Publikováno v:
Operations Management Research.
After decades of huge production offshoring, companies are increasingly re-evaluating their production footprint, often implementing so-called reshoring strategies. Among them scarce attention has been devoted to the near-shoring option, i.e., reloca
Autor:
Alexander Schinagl, Randolf J. Kerschbaumer, Michael Thiele, Julia Mayer, Verena Hoeld, Barbara Maurer, Irina Mirkina, Gregor Rossmueller
Pharmacokinetics and BD of C0008, C0083, and C0090. A, BALB/c nude mice received a single intravenous injection of C0008, C0083, and C0090 mAbs (10 mg/kg), and plasma samples were collected 4, 10, 24, 48, and 96 hours thereafter. The plasma concentra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::209cee8e4651945929eaa3ce43d5adbf
https://doi.org/10.1158/1535-7163.22758809
https://doi.org/10.1158/1535-7163.22758809
Autor:
Alexander Schinagl, Randolf J. Kerschbaumer, Michael Thiele, Julia Mayer, Verena Hoeld, Barbara Maurer, Irina Mirkina, Gregor Rossmueller
Physicochemical characterization of the mAb variants revealed identical binding properties and reduced hydrophobicity of the bioengineered anti-oxMIF antibodies compared with C0008 (imalumab). A, Antibody specificity of oxMIF versus redMIF in solutio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47c8bc223a50a5bf55f0b3a95751c24b
https://doi.org/10.1158/1535-7163.22758812.v1
https://doi.org/10.1158/1535-7163.22758812.v1