Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Julia Margulis"'
Autor:
Eric J. Huang, Zak Doric, Hiromi Sesaki, Amandine Berthet, Steve Finkbeiner, Ivy Hsieh, Jayanta Debnath, Mai K. Nguyen, Rebecca Fang, Ken Nakamura, Huihui Li, Julia Margulis, Danielle M. Jorgens
Publikováno v:
Science Advances
Time-lapse imaging delineates the mitochondrial life cycle in neurons regulated by PINK1 and Parkin.
Altered mitochondrial quality control and dynamics may contribute to neurodegenerative diseases, including Parkinson’s disease, but we underst
Altered mitochondrial quality control and dynamics may contribute to neurodegenerative diseases, including Parkinson’s disease, but we underst
Autor:
Sandrine Humbert, Daniel J. Klionsky, Kai Mao, Julia Margulis, Joan S. Steffan, Steven Finkbeiner, Joseph Ochaba, Alice L. Lau, Shuqiu Zheng, Lisa Salazar, Tamas Lukacsovich, George Csikos, Frédéric Saudou, Scott Zeitlin, Sylvia Y. Yeung, J. Lawrence Marsh, Leslie M. Thompson, David E. Housman
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 111, iss 47
Ochaba, J; Lukacsovich, T; Csikos, G; Zheng, S; Margulis, J; Salazar, L; et al.(2014). Potential function for the Huntingtin protein as a scaffold for selective autophagy. Proceedings of the National Academy of Sciences of the United States of America, 111(47), 16889-16894. doi: 10.1073/pnas.1420103111. UCSF: Retrieved from: http://www.escholarship.org/uc/item/33x3781x
Ochaba, J; Lukacsovich, T; Csikos, G; Zheng, S; Margulis, J; Salazar, L; et al.(2014). Potential function for the Huntingtin protein as a scaffold for selective autophagy. Proceedings of the National Academy of Sciences of the United States of America, 111(47), 16889-16894. doi: 10.1073/pnas.1420103111. UCSF: Retrieved from: http://www.escholarship.org/uc/item/33x3781x
Although dominant gain-of-function triplet repeat expansions in the Huntingtin (HTT) gene are the underlying cause of Huntington disease (HD), understanding the normal functions of nonmutant HTT protein has remained a challenge. We report here findin
Autor:
Erik R. Abels, Julia Margulis, Steve Finkbeiner, Xuan Zhang, Jasmina S. Redzic, Xandra O. Breakefield
Publikováno v:
Cellular and molecular neurobiology, vol 36, iss 3
In Huntington's disease (HD) the imperfect expanded CAG repeat in the first exon of the HTT gene leads to the generation of a polyglutamine (polyQ) protein, which has some neuronal toxicity, potentially mollified by formation of aggregates. Accumulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::145febc74ae34b3837faf11e1c5424e2
https://escholarship.org/uc/item/5vx201wt
https://escholarship.org/uc/item/5vx201wt