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of 7
pro vyhledávání: '"Julia Makhlin"'
Autor:
Jason Michael Patapas, Dusica Maysinger, Maria Petropavlovskaia, Jeff Ji, Armen Khatchadourian, Julia Makhlin, Lawrence Rosenberg
Publikováno v:
Journal of Cellular and Molecular Medicine
Both type 2 diabetes (T2D) and obesity are characterized by excessive hyperlipidaemia and subsequent lipid droplet (LD) accumulation in adipose tissue. To investigate whether LDs also accumulate in β‐cells of T2D patients, we assessed the expressi
Autor:
Béatrice Assouline-Thomas, Maria Petropavlovskaia, Jonathan Zhu, Lawrence Rosenberg, Julia Makhlin, Jieping Ding, Jamal Daoud, Mandana Moosavi
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 303:E917-E927
Islet neogenesis-associated protein (INGAP) was discovered in the partially duct-obstructed hamster pancreas as a factor inducing formation of new duct-associated islets. A bioactive portion of INGAP, INGAP104–118peptide (INGAP-P), has been shown t
Publikováno v:
Journal of Endocrinology. 211:231-239
Given the inherent therapeutic potential of the morphogenetic plasticity of adult human islets, the identification of factors controlling their cellular differentiation is of interest. The epidermal growth factor (EGF) family has been identified prev
Autor:
Béatrice Assouline-Thomas, David V. McLeod, Julia Makhlin, Jieping Ding, Maria Petropavlovskaia, Amélie Pilotte, Stephen C. Hanley, Bernard Massie, Lawrence Rosenberg
Publikováno v:
Protein Expression and Purification. 69:1-8
Islet Neogenesis Associated Protein (INGAP) is implicated in pancreatic islet neogenesis. INGAP peptide, a pentadecapeptide comprising amino acids 104–118, reverses diabetes in rodents and improves glucose homeostasis in patients with diabetes. The
Autor:
Tzili Kofman, Ilya Borovok, Christian Kohler, Yair Aharonowitz, Susanne Engelmann, Julia Makhlin, Gerald Cohen
Publikováno v:
Journal of Bacteriology. 189:5976-5986
We identified a single open reading frame that is strongly similar to ArcR, a member of the Crp/Fnr family of bacterial transcriptional regulators, in all sequenced Staphylococcus aureus genomes. The arcR gene encoding ArcR forms an operon with the a
Autor:
Lawrence Rosenberg, Maria Petropavlovskaia, Daniel Ellis, Julia Makhlin, Jieping Ding, Béatrice Assouline-Thomas
Publikováno v:
Differentiation; research in biological diversity. 90(4-5)
Regeneration of β-cells in diabetic patients is an important goal of diabetes research. Islet Neogenesis Associated Protein (INGAP) was discovered in the partially duct-obstructed hamster pancreas. Its bioactive fragment, pentadecapeptide 104-118 (I
Publikováno v:
The Journal of endocrinology. 191(1)
Restoration of a functional β-cell mass in a patient with diabetes may hold the key for curing the disease. In recent years, there has been increasing interest in the development of new strategies to induce β-cell regeneration and new islet formati