Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Julia M.R. Billington"'
Autor:
Xue-Zhong Yu, John M. Koomen, Nicholas J. Lawrence, Mario R. Fernandez, William E. Goodheart, John L. Cleveland, Adam W. Mailloux, Ying Han, Anjali M. Rajadhyaksha, Muhammad Ayaz, Sang Y Yun, Matthew Beatty, Afua A. Akuffo, Jianing Fu, Timothy J. Garrett, Lancia Darville, Pearlie K. Epling-Burnette, Robert J. Gillies, Lanzhu Yue, Chunying Yang, Shiun Chang, Kun Jiang, Aileen Y. Alontaga, Rebecca S Hesterberg, Julia M.R. Billington, Jessica M. McDaniel, Jane L. Messina, Harshani R. Lawrence, Christelle M. Colin, Xiubao Ren, Shonagh Russell
Publikováno v:
Blood
Immunomodulatory drugs, such as thalidomide and related compounds, potentiate T-cell effector functions. Cereblon (CRBN), a substrate receptor of the DDB1-cullin-RING E3 ubiquitin ligase complex, is the only molecular target for this drug class, wher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c96ac76a73d87efec574673d4fa6f062
https://europepmc.org/articles/PMC7426646/
https://europepmc.org/articles/PMC7426646/
Autor:
Ross L. Levine, Chiara Conti, Lanzhu Yue, Eva Sahakian, Nathan P. Horvat, Amit Verma, John Powers, Narmin E. Amin, Afua A. Akuffo, Kenneth L. Wright, C. Gary Marshall, Pui Yee Ng, Ling Zhang, Javier Pinilla-Ibarz, Xiaozhang Zheng, John M. Koomen, Julia M.R. Billington, Zonghong Shao, Matthew Beatty, Lancia Darville, Christelle M. Colin, Pearlie K. Epling-Burnette, Eduardo M. Sotomayor, Que T. Lambert-Showers, Jennifer Y. Lee, Matthew W. Martin, Gary W. Reuther, Cem Murdun, H. Leighton Grimes, William E. Goodheart, Vasundhara Sharma
Publikováno v:
Blood
Protein acetylation is an important contributor to cancer initiation. Histone deacetylase 6 (HDAC6) controls JAK2 translation and protein stability and has been implicated in JAK2-driven diseases best exemplified by myeloproliferative neoplasms (MPNs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::634ceea44a77557b60fe813516a9e8b7
https://pubmed.ncbi.nlm.nih.gov/31750881
https://pubmed.ncbi.nlm.nih.gov/31750881
Autor:
Eduardo M. Sotomayor, Ross L. Levine, Narmin E. Amin, Julia M.R. Billington, Amit Verma, John Powers, Nathan P. Horvat, Zonghong Shao, Lancia Darville, Pearlie K. Epling-Burnette, Afua A. Akuffo, Kenneth P. Wright, H. Leighton Grimes, Cem Murdun, Gary C. Marshall, Vasundhara Sharma, Gary W. Reuther, Ling Zhang, Xiaozhang Zheng, Que T. Lambert-Showers, Mathew W. Martin, Jennifer Lee, Pui Yee Ng, Mathew Beatty, Lanzhu Yue, John M. Koomen, Eva Sahakian, Agni Christodoulidou, William E. Goodheart, Javier Pinilla Ibarz
Publikováno v:
Blood. 134:474-474
Introduction: Acetylated histone and non-histone proteins are pharmacologic targets for both solid and hematological cancers including myeloproliferative neoplasms (MPNs), a group of clonal hematological malignancies driven by aberrant JAK2/STAT sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f559c691cb93214f84ccd1cf335b79a3
https://doi.org/10.1182/blood-2019-127235
https://doi.org/10.1182/blood-2019-127235