Výsledky vyhledávání - "Julia M. Sugalski"

Natural Cytotoxicity Receptor–Dependent Natural Killer Cytolytic activity Directed at Hepatitis C Virus (HCV) Is Associated With Liver Inflammation, African American Race, IL28B Genotype, and Response to Pegylated Interferon/Ribavirin Therapy in Chronic HCV Infection

Autor: M. R. Sandhya Rani, Julia M. Sugalski, Ronald E. Blanton, Sarah Phat, Chelsey J. Judge, Donald D. Anthony, Qinglai Meng, Benigno Rodriguez

Publikováno v: The Journal of Infectious Diseases. 209:1591-1601

Factors associated with response to pegylated interferon-α/ribavirin (peg-IFN/RBV) include hepatitis C virus (HCV) genotype, age, race, human immunodeficiency virus (HIV) coinfection, baseline HCV level, and IL28B gene locus polymorphism [1–7]. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4811c9be6a800c622fda64d655405bae
https://doi.org/10.1093/infdis/jit677

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Genetically Associated CD16+56− Natural Killer Cell Interferon (IFN)–αR Expression Regulates Signaling and Is Implicated in IFN-α–Induced Hepatitis C Virus Decline

Autor: Nicole L. Yonkers, Gareth Hardy, Sara J. Conry, Donald D. Anthony, Perica Davitkov, Clifford V. Harding, Anita Compan, Qinglai Meng, Amy Hirsch, Benigno Rodriguez, Ronald E. Blanton, Julia M. Sugalski, Yngve Falck-Ytter

Publikováno v: The Journal of Infectious Diseases. 205:1131-1141

Acute hepatitis C virus (HCV) infection becomes persistent in a majority of cases [1], and the long-term risk of cirrhosis, liver failure, cancer, and mortality among those with chronic infection highlight the importance of effective therapy [1, 2].

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05513f30ef980d0d68161c10f7444e01
https://doi.org/10.1093/infdis/jis027

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Plasma proteome analysis reveals overlapping, yet distinct mechanisms of immune activation in chronic HCV and HIV infections

Autor: Fred E. Hazlett, Nicholas T. Funderburg, Julia M. Sugalski, Michael M. Lederman, Scott F. Sieg, Donald D. Anthony, Jill S. Barnholtz-Sloan, Mark R. Chance, Yanwen Chen, Daniela Schlatzer, Perica Davitkov, Benigno Rodriguez

Publikováno v: Journal of acquired immune deficiency syndromes (1999). 63(5)

Background HIV infection contributes to accelerated rates of progression of liver fibrosis during hepatitis C virus (HCV) infection, and HCV liver disease contributes to mortality during HIV infection. Although mechanisms underlying these interaction

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::595b412a125b7b03811a99f6928fee05
https://pubmed.ncbi.nlm.nih.gov/23507661

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A quantitative proteomic approach for detecting protein profiles of activated human myeloid dendritic cells

Autor: Jean-Eudes Dazard, Donald D. Anthony, Mark R. Chance, Daniela Schlatzer, Julia M. Sugalski

Publikováno v: Journal of immunological methods. 375(1-2)

Dendritic cells (DC) direct the magnitude, polarity and effector function of the adaptive immune response. DC express toll-like receptors (TLR), antigen capturing and processing machinery, and costimulatory molecules, which facilitate innate sensing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca98b70297e1594f4367682beb3604c8
https://pubmed.ncbi.nlm.nih.gov/21945394

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Peripheral blood B cell subset skewing is associated with altered cell cycling and intrinsic resistance to apoptosis and reflects a state of immune activation in chronic hepatitis C virus infection

Autor: Donald D. Anthony, Julia M. Sugalski, Susan Moir, Benigno Rodriguez

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 185(5)

Chronic hepatitis C virus (HCV) infection is associated with B cell activation, although underlying mechanisms are unclear. To investigate B cell regulation during HCV infection, we measured bulk B cell CpG and Staphylococcus aureus Cowan-induced IgG

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e365e9fbdced7bc4c92a972b3475d90
https://pubmed.ncbi.nlm.nih.gov/20656924

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