Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Julia M. Martínez-Gómez"'
Autor:
Rajia Bahri, Orsolya Kiss, Ian Prise, Karen M. Garcia-Rodriguez, Haris Atmoko, Julia M. Martínez-Gómez, Mitchell P. Levesque, Reinhard Dummer, Michael P. Smith, Claudia Wellbrock, Silvia Bulfone-Paus
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Cutaneous melanoma is one of the most aggressive human malignancies and shows increasing incidence. Mast cells (MCs), long-lived tissue-resident cells that are particularly abundant in human skin where they regulate both innate and adaptive immunity,
Externí odkaz:
https://doaj.org/article/65e963f136964a6b9f153b7ea594d82a
Autor:
Ulrike Lischetti, Aizhan Tastanova, Franziska Singer, Linda Grob, Matteo Carrara, Phil F. Cheng, Julia M. Martínez Gómez, Federica Sella, Veronika Haunerdinger, Christian Beisel, Mitchell P. Levesque
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-16 (2023)
Abstract Multi-omics profiling by CITE-seq bridges the RNA-protein gap in single-cell analysis but has been largely applied to liquid biopsies. Applying CITE-seq to clinically relevant solid biopsies to characterize healthy tissue and the tumor micro
Externí odkaz:
https://doaj.org/article/0ca7c687976342d7944098a427595259
Autor:
Simon Burgermeister, Hubert S. Gabryś, Lucas Basler, Sabrina A. Hogan, Matea Pavic, Marta Bogowicz, Julia M. Martínez Gómez, Diem Vuong, Stephanie Tanadini-Lang, Robert Foerster, Martin W. Huellner, Reinhard Dummer, Mitchell P. Levesque, Matthias Guckenberger
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
PurposeWe explored imaging and blood bio-markers for survival prediction in a cohort of patients with metastatic melanoma treated with immune checkpoint inhibition.Materials and Methods94 consecutive metastatic melanoma patients treated with immune c
Externí odkaz:
https://doaj.org/article/df2738f114d24e2a825402237ac970e7
Autor:
Roy Rabbie, Naser Ansari-Pour, Oliver Cast, Doreen Lau, Francis Scott, Sarah J. Welsh, Christine Parkinson, Leila Khoja, Luiza Moore, Mark Tullett, Kim Wong, Ingrid Ferreira, Julia M. Martínez Gómez, Mitchell Levesque, Ferdia A. Gallagher, Alejandro Jiménez-Sánchez, Laura Riva, Martin L. Miller, Kieren Allinson, Peter J. Campbell, Pippa Corrie, David C. Wedge, David J. Adams
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Metastatic melanoma is associated with a poor prognosis and understanding the genetic features of metastases may enable better treatment strategies. Here, the authors analyse multiple metastases from individual patients finding high levels of heterog
Externí odkaz:
https://doaj.org/article/88af25cb99664cab9677a9f33b3cdf38
Autor:
Simon, Burgermeister, Hubert S, Gabryś, Lucas, Basler, Sabrina A, Hogan, Matea, Pavic, Marta, Bogowicz, Julia M, Martínez Gómez, Diem, Vuong, Stephanie, Tanadini-Lang, Robert, Foerster, Martin W, Huellner, Reinhard, Dummer, Mitchell P, Levesque, Matthias, Guckenberger
Publikováno v:
Frontiers in oncology. 12
We explored imaging and blood bio-markers for survival prediction in a cohort of patients with metastatic melanoma treated with immune checkpoint inhibition.94 consecutive metastatic melanoma patients treated with immune checkpoint inhibition were in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4441f7449313c368ca92e0c7e25fdaca
https://pubmed.ncbi.nlm.nih.gov/35494048
https://pubmed.ncbi.nlm.nih.gov/35494048
Autor:
Bernd Bodenmiller, Nils Eling, Tobias Hoch, Mitchell P. Levesque, Julia M. Martínez Gómez, Daniel Schulz
Intratumoral immune cells are crucial for tumor control and anti-tumor responses during immunotherapy. Immune cell trafficking into tumors is mediated by chemokines, which are expressed and secreted upon various stimuli and interact with specific rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::909beb4463f163e0b4ed1560b01829e5
https://doi.org/10.1101/2021.07.29.454093
https://doi.org/10.1101/2021.07.29.454093
Publikováno v:
PLoS ONE, Vol 9, Iss 1 (2014)
Externí odkaz:
https://doaj.org/article/722aee7800364151896b5a9d2149a010
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73277 (2013)
BACKGROUND: CD137 and its ligand (CD137L) are potent immunoregulatory molecules that influence activation, proliferation, differentiation and cell death of leukocytes. Expression of CD137 is upregulated in the lamina propria cells of Crohn's disease
Externí odkaz:
https://doaj.org/article/439dea4b8166490a86a60137fba2290f
Autor:
Luiza Moore, David J. Adams, Alejandro Jiménez-Sánchez, Mark Tullett, Laura Riva, Kim Wong, David C. Wedge, Martin L. Miller, Sarah J. Welsh, Doreen Lau, Christine Parkinson, Julia M. Martínez Gómez, Kieren Allinson, Pippa Corrie, Ingrid Ferreira, Francis Scott, Leila Khoja, Roy Rabbie, Naser Ansari-Pour, Peter J. Campbell, Mitchell P. Levesque, Ferdia A. Gallagher, Oliver Cast
Publikováno v:
Nature communications, 11 (1
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Rabbie, R, Ansari-pour, N, Cast, O, Lau, D, Scott, F, Welsh, S J, Parkinson, C, Khoja, L, Moore, L, Tullett, M, Wong, K, Ferreira, I, Gómez, J M M, Levesque, M, Gallagher, F A, Jiménez-sánchez, A, Riva, L, Miller, M L, Allinson, K, Campbell, P J, Corrie, P, Wedge, D C & Adams, D J 2020, ' Multi-site clonality analysis uncovers pervasive heterogeneity across melanoma metastases ', Nature Communications, vol. 11, no. 1 . https://doi.org/10.1038/s41467-020-18060-0
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Rabbie, R, Ansari-pour, N, Cast, O, Lau, D, Scott, F, Welsh, S J, Parkinson, C, Khoja, L, Moore, L, Tullett, M, Wong, K, Ferreira, I, Gómez, J M M, Levesque, M, Gallagher, F A, Jiménez-sánchez, A, Riva, L, Miller, M L, Allinson, K, Campbell, P J, Corrie, P, Wedge, D C & Adams, D J 2020, ' Multi-site clonality analysis uncovers pervasive heterogeneity across melanoma metastases ', Nature Communications, vol. 11, no. 1 . https://doi.org/10.1038/s41467-020-18060-0
Metastatic melanoma carries a poor prognosis despite modern systemic therapies. Understanding the evolution of the disease could help inform patient management. Through whole-genome sequencing of 13 melanoma metastases sampled at autopsy from a treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::095bdd688d2e81502047a9bcbc7554f0
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/312055
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/312055
Autor:
Ido Livneh, Keith T. Flaherty, Lea Feld, Gao Zhang, Brian P. James, Kevin K. Brown, Bertrand Fabre, Yongmei Feng, Jeny Shklover, Haguy Wolfenson, Patrick Turko, Ze'ev Ronai, Meenhard Herlyn, Ali Khateb, Emily Avitan-Hersh, Mitchell P. Levesque, Reinhard Dummer, Ola Larsson, Ikrame Lazar, Tongwu Zhang, Julia M. Martínez Gómez, Marzia Scortegagna, Ivan Topisirovic, Dennie T. Frederick
Publikováno v:
Mol Cancer Res
Mechanisms regulating nuclear organization control fundamental cellular processes, including the cell and chromatin organization. Their disorganization, including aberrant nuclear architecture, has been often implicated in cellular transformation. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a0c45f077182ec10a89ca125eccb7f0
https://europepmc.org/articles/PMC7541784/
https://europepmc.org/articles/PMC7541784/