Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Julia M. Knelangen"'
Autor:
Bernd Fischer, Elen Gocza, Katarzyna J. Grybel, Anne Navarrete Santos, Jacqueline Gürke, Julia M. Knelangen, Maria Schindler, S. Mareike Pendzialek
Publikováno v:
Molecular and Cellular Endocrinology. 480:167-179
MicroRNAs are promising biological markers for prenatal diagnosis. They regulate placental development and are present in maternal plasma. Maternal metabolic diseases are major risk factors for placental deterioration. We analysed the influence of a
Maternal Diabetes Leads to Unphysiological High Lipid Accumulation in Rabbit Preimplantation Embryos
Autor:
Alexander Navarrete Santos, Maria Schindler, Anne Navarrete Santos, Stefanie Seyring, Torsten Plösch, Bernd Fischer, Elisa Haucke, Mareike Pendzialek, Jacqueline Gürke, Julia M. Knelangen
Publikováno v:
Endocrinology, 155(4), 1498-1509. ENDOCRINE SOC
According to the “developmental origin of health and disease” hypothesis, the metabolic set points of glucose and lipid metabolism are determined prenatally. In the case of a diabetic pregnancy, the embryo is exposed to higher glucose and lipid c
Autor:
Julia M. Knelangen, Julie A. Owens, Anne Navarrete Santos, Mark B. van der Hoek, Bernd Fischer, Wee-Ching Kong
Publikováno v:
Physiological Genomics. 43:611-620
Pluripotent embryonic stem cells (ESC) have the potential to differentiate into any cell type of the three germ layers. Differentiation processes depend on genetic and epigenetic factors. The guidance of cell fate determination by microRNAs (miRs) se
Autor:
Kristina Schaedlich, Alexander Navarrete Santos, Bernd Fischer, Anne Navarrete Santos, Julia M. Knelangen
Publikováno v:
Cytometry Part A. :990-995
Because of the increasing incidence of worldwide obesity, cell culture models which enable the study of adipose tissue development are of particular importance. The murine embryonic stem cell (ESC) line CGR8 differentiates into adipocytes with a diff
Autor:
Mareike Pendzialek, Sylvain Fischer, Jacqueline Gürke, A Navarrete Santos, Bernd Fischer, Maria Schindler, René Thieme, Elisa Haucke, Julia M. Knelangen
Publikováno v:
Experimental and Clinical Endocrinology & Diabetes. 122
Maternal insulin and insulin-like growth factors (IGFs) promote development and growth of preimplantation embryos. They regulate differentiation-specific gene expression and balance embryonic energy and glucose metabolism. Changes in maternal metabol
Autor:
Maria Schindler, Mareike Pendzialek, E. Hauke, Torsten Plösch, Julia M. Knelangen, Jacqueline Gürke, A. Navarrete Santos, Bernd Fischer
Publikováno v:
Reproduction, Fertility and Development. 25:587
The incidence of overweight and obesity has reached epidemic levels worldwide. Even more alarming is the increasing prevalence of metabolic diseases in younger children and adolescents. The rate of women with diabetes mellitus in child-bearing age is