Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Julia M. Huber"'
Autor:
Arno Amann, Marit Zwierzina, Stefan Koeck, Gabriele Gamerith, Elisabeth Pechriggl, Julia M. Huber, Edith Lorenz, Jens M. Kelm, Wolfgang Hilbe, Heinz Zwierzina, Johann Kern
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract The tumour microenvironment and tumour angiogenesis play a critical role in the development and therapy of many cancers, but in vitro models reflecting these circumstances are rare. In this study, we describe the development of a novel tri-c
Externí odkaz:
https://doaj.org/article/1ee938a72b3246ccbd4db879b442a84b
Autor:
Hubert Hackl, Gabriele Gamerith, Zlatko Trajanoski, Julia M. Huber, Jens M. Kelm, Johannes Rainer, Johann Kern, Edith Lorenz, Heinz Zwierzina, Reinhard Kofler, Arno Amann, Stefan Koeck
Publikováno v:
Oncotarget. 8:112647-112661
This work evaluated gene expression differences between a hanging-drop 3D NSCLC model and 2D cell cultures and their in-vivo relevance by comparison to patient-derived data from The Cancer Genome Atlas. Gene expression of 2D and 3D cultures for Colo6
Autor:
Edith Lorenz, Gabriele Gamerith, Stefan Koeck, Elisabeth J. Pechriggl, Heinz Zwierzina, Johann Kern, Arno Amann, Marit Zwierzina, Wolfgang Hilbe, Julia M. Huber, Jens M. Kelm
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports
Scientific Reports
The tumour microenvironment and tumour angiogenesis play a critical role in the development and therapy of many cancers, but in vitro models reflecting these circumstances are rare. In this study, we describe the development of a novel tri-culture mo
Autor:
Petra Obexer, Jens M. Kelm, Gabriele Gamerith, Arno Amann, Edith Lorenz, Heinz Zwierzina, Julia M. Huber, Stefan Koeck
Publikováno v:
Journal of Cancer Research and Clinical Oncology
Background The focus of the outlined work is the establishment of a three-dimensional lung model for various drug-screening applications. Methods The non-small cell lung cancer (NSCLC) cell line Colo699 was cultivated as monolayer (2D) on plates for
Autor:
Stefan Koeck, Mario Bitsche, Julia M. Huber, Edith Lorenz, Marit Zwierzina, Heinz Zwierzina, Arno Amann, Jozsef Dudas, Jens M. Kelm, Gabriele Gamerith
Publikováno v:
Immunobiology. 221:604-617
Introduction The interaction between the immune system and malignant diseases is a proven key target for cancer therapy. We describe an innovative 3D cell culture system comprising both immune and cancer cells to evaluate their interaction and immune
Autor:
Arno Amann, Gabriele Gamerith, Julia M. Huber, Marit Zwierzina, Heinz Zwierzina, Wolfgang Hilbe
Publikováno v:
memo - Magazine of European Medical Oncology. 8:77-80
Because of recent failures of novel drugs in phase II and III trials innovative in vitro models are needed that may predict drug efficacy in patients. Although, numerous modifications of traditional cell culture and animal models were undertaken sign
Autor:
Julia M. Huber, Maximilian Boesch, Helmut Klocker, Guenther Gastl, Dominik Wolf, Sieghart Sopper, Alain G. Zeimet, Barbara Wolf, Heidi Fiegl
Publikováno v:
Oncoscience
Cancer cell lines are essential platforms for performing cancer research on human cells. We here demonstrate that, across tumor entities, human cancer cell lines harbor minority populations of putative stem-like cells, molecularly defined by dye extr
Autor:
Gabriele, Gamerith, Johannes, Rainer, Julia M, Huber, Hubert, Hackl, Zlatko, Trajanoski, Stefan, Koeck, Edith, Lorenz, Johann, Kern, Reinhard, Kofler, Jens M, Kelm, Heinz, Zwierzina, Arno, Amann
Publikováno v:
Oncotarget
This work evaluated gene expression differences between a hanging-drop 3D NSCLC model and 2D cell cultures and their in-vivo relevance by comparison to patient-derived data from The Cancer Genome Atlas. Gene expression of 2D and 3D cultures for Colo6
Autor:
Ivan Tancevski, Andreas Wehinger, Ruediger Seiler, Josef R. Patsch, Philipp Eller, Sandra Frotschnig, Andreas Ritsch, Bernhard Foeger, Stefan Frantz, Julia M. Huber, Wilfried Schgoer
Publikováno v:
Atherosclerosis. 206:234-238
Background We recently showed that aspirin promotes scavenger receptor class-B type I (SR-BI) protein expression in vitro in primary human macrophages and in vivo in resident peritoneal macrophages of mice. Methods We compared SR-BI and CD68 expressi
Autor:
Julia M. Huber, Mats Rudling, Andreas Ritsch, Frans Stellaard, Egon Demetz, Wilfried Schgoer, Kristina Duwensee, Ivan Tancevski, Kathrin Hochegger, Catherine Fievet, Andreas Wehinger, Philipp Eller, Josef R. Patsch
Publikováno v:
Endocrinology, 149(7), 3708-3712. ENDOCRINE SOC
The aim of the study was to investigate the influence of severe hyperthyroidism on plasma high-density lipoprotein cholesterol (HDL-C). Recently, it was shown in mice that increasing doses of T3 up-regulate hepatic expression of scavenger receptor cl