Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Julia M. Carr"'
Autor:
J. Simon C. Arthur, Christopher J. Hunter, Kirsty J. Martin, Andrew D. Wingate, Carol Clacher, Julia M. Carr
Publikováno v:
genesis. 47:688-696
Phosphorylation of Ser133 in the transcription factor CREB is an important mechanism for regulating its transcriptional activity, however recent work has suggested significant roles for other regulatory inputs into CREB. To allow study of this in viv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf81b0e03fdbe5c89daf304e432ab980
https://doi.org/10.1002/dvg.20548
https://doi.org/10.1002/dvg.20548
Autor:
Susana G. Santos, Joanne McIlrath, Julia M. Carr, Claus Johansen, Jin Mo Park, Olga Ananieva, Lars Iversen, J. Simon C. Arthur, Andrew D. Wingate, Claire E. Monk, Rachel Toth, Joanne Darragh
Publikováno v:
Ananieva, O, Darragh, J, Johansen, C, Carr, J M, McIlrath, J, Park, J M, Wingate, A, Monk, C E, Toth, R, Santos, S G, Iversen, L & Arthur, J S C 2008, ' The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling. ', Nature Immunology, vol. 9, no. 9, pp. 1028-36 . https://doi.org/10.1038/ni.1644
Udgivelsesdato: 2008-Sep The kinases MSK1 and MSK2 are activated 'downstream' of the p38 and Erk1/2 mitogen-activated protein kinases. Here we found that MSK1 and MSK2 were needed to limit the production of proinflammatory cytokines in response to st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c08a735a06e93c5813bf1a957a17428
https://doi.org/10.1038/ni.1644
https://doi.org/10.1038/ni.1644
Autor:
J. Simon C. Arthur, Victoria A. Beardmore, Christina Eftychi, Joanne McIlrath, Loraine Malone, Heather J. Hinton, Maria Armaka, Maria Apostolaki, Carol Clacher, George Kollias, Julia M. Carr, Laura J. Armit, Joanne Darragh
Publikováno v:
Molecular and Cellular Biology. 25:10454-10464
Mitogen-activated protein kinase (MAPK) cascades are important mediators of the cellular response to a wide variety of extracellular signals, including mitogens, growth factors, cytokines, and cellular stress (reviewed in references 22 and 30). There
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c897e9181721cffb877a329e71c3c8a8
https://doi.org/10.1128/mcb.25.23.10454-10464.2005
https://doi.org/10.1128/mcb.25.23.10454-10464.2005
Autor:
Kei Sakamoto, J. Simon C. Arthur, Eric Hajduch, Victoria A. Beardmore, Julia M. Carr, Sophie Turban, Harinder S. Hundal
Publikováno v:
Diabetes. 54:3161-3168
It has been proposed that p38 mitogen-activated protein kinase (MAPK) isoforms sensitive to the pyridinylimidazole compounds SB 203580 and SB 202190 may participate in the acute insulin-dependent activation of glucose transporters recruited to the pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afb784d0188dd6f0f8af864df9ee3434
https://doi.org/10.2337/diabetes.54.11.3161
https://doi.org/10.2337/diabetes.54.11.3161
p38γ regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP
Autor:
James Simon Campbell Arthur, Michel Goedert, Vicky Murray-Tait, Ana Cuenda, Yvonne Kuma, Nicholas A. Morrice, Julia M. Carr, Guadalupe Sabio, Mark Peggie, Francisco Centeno
Publikováno v:
The EMBO Journal. 24:1134-1145
Activation of the p38 MAP kinase pathways is crucial for the adaptation of mammalian cells to changes in the osmolarity of the environment. Here we identify SAP97/hDlg, the mammalian homologue of the Drosophila tumour suppressor Dlg, as a physiologic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69b8c9903320b13bc99f3a023baec188
https://doi.org/10.1038/sj.emboj.7600578
https://doi.org/10.1038/sj.emboj.7600578
Autor:
Julia M. Carr, Peter R. Ashby, Calum Thompson, Victoria Murry-Tait, J. Simon C. Arthur, Lijun Yan
Publikováno v:
BMC Developmental Biology
BMC Developmental Biology, Vol 3, Iss 1, p 11 (2003)
BMC Developmental Biology, Vol 3, Iss 1, p 11 (2003)
Backgroud ERK5 is a member of the mitogen activated protein kinase family activated by certain mitogenic or stressful stimuli in cells, but whose physiological role is largely unclear. Results To help determine the function of ERK5 we have used gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96e35b8894ff95d8334b2f59f31565ec
https://pubmed.ncbi.nlm.nih.gov/14675480
https://pubmed.ncbi.nlm.nih.gov/14675480