Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Julia M. Assini"'
Autor:
Alexandria M. Doerfler, So Hyun Park, Julia M. Assini, Amer Youssef, Lavanya Saxena, Adam B. Yaseen, Marco De Giorgi, Marcel Chuecos, Ayrea E. Hurley, Ang Li, Santica M. Marcovina, Gang Bao, Michael B. Boffa, Marlys L. Koschinsky, William R. Lagor
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 27, Iss , Pp 337-351 (2022)
Lipoprotein(a) (Lp(a)) represents a unique subclass of circulating lipoprotein particles and consists of an apolipoprotein(a) (apo(a)) molecule covalently bound to apolipoprotein B-100. The metabolism of Lp(a) particles is distinct from that of low-d
Externí odkaz:
https://doaj.org/article/e69bb16736e64616a0e3d81f0b495788
Autor:
Martina B. Lorey, Amer Youssef, Lauri Äikäs, Matthew Borrelli, Martin Hermansson, Julia M. Assini, Aapeli Kemppainen, Hanna Ruhanen, Maija Ruuth, Sampsa Matikainen, Petri T. Kovanen, Reijo Käkelä, Michael B. Boffa, Marlys L. Koschinsky, Katariina Öörni
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
IntroductionLipoprotein(a) (Lp(a)) is an LDL-like particle with an additional apolipoprotein (apo)(a) covalently attached. Elevated levels of circulating Lp(a) are a risk factor for atherosclerosis. A proinflammatory role for Lp(a) has been proposed,
Externí odkaz:
https://doaj.org/article/e718ebe0203e44b68e68438c5b4d9562
Autor:
Julia M. Assini, Erin E. Mulvihill, Brian G. Sutherland, Dawn E. Telford, Cynthia G. Sawyez, Sarah L. Felder, Sanjiv Chhoker, Jane Y. Edwards, Robert Gros, Murray W. Huff
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 3, Pp 711-724 (2013)
Obesity-associated chronic inflammation contributes to metabolic dysfunction and propagates atherosclerosis. Recent evidence suggests that increased dietary cholesterol exacerbates inflammation in adipose tissue and liver, contributing to the proathe
Externí odkaz:
https://doaj.org/article/158247674e644e5aa756021704b6e7ce
Autor:
Julia M. Assini, Justin R. Clark, Amer Youssef, Chuce Xing, Alexandria M. Doerfler, So Hyun Park, Lavanya Saxena, Adam B. Yaseen, Jan Børen, Robert Gros, Gang Bao, William R. Lagor, Michael B. Boffa, Marlys L. Koschinsky
Publikováno v:
Atherosclerosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a433c03a2707122bc2666c2dc9a98e0
https://doi.org/10.1016/j.atherosclerosis.2023.05.019
https://doi.org/10.1016/j.atherosclerosis.2023.05.019
Autor:
Alexandria M. Doerfler, So Hyun Park, Julia M. Assini, Amer Youssef, Lavanya Saxena, Adam B. Yaseen, Marco De Giorgi, Marcel Chuecos, Ayrea E. Hurley, Ang Li, Santica M. Marcovina, Gang Bao, Michael B. Boffa, Marlys L. Koschinsky, William R. Lagor
Lipoprotein(a) (Lp(a)) represents a unique subclass of circulating lipoprotein particles and consists of an apolipoprotein( a) (apo(a)) molecule covalently bound to apolipoprotein B-100. The metabolism of Lp(a) particles is distinct from that of low-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74848f096aa6cdece6c2f81a24941cdf
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42
Despite increased clinical interest in the unique lipoprotein Lp(a), many questions remain about the molecular mechanisms by which it contributes to atherosclerotic cardiovascular disease. To address this knowledge gap we generated transgenic mice ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::334a2c9a75fb0d780559b5653cf10c65
https://doi.org/10.1161/atvb.42.suppl_1.215
https://doi.org/10.1161/atvb.42.suppl_1.215
Publikováno v:
Circulation Research. 115:542-545
Much of our understanding of normal low-density lipoprotein (LDL) cholesterol metabolism can be traced to studies in human carriers of naturally occurring mutations, which perturb proteins acting at key metabolic checkpoints.1 The best known among th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fd16cfaaacdcc9da47fbcac9959bf2d
https://doi.org/10.1161/circresaha.114.304800
https://doi.org/10.1161/circresaha.114.304800
Autor:
Erin E. Mulvihill, Cynthia G. Sawyez, Brian G. Sutherland, Dawn E. Telford, Robert Gros, Sarah L. Felder, Jane Y. Edwards, Julia M. Assini, Murray W. Huff, Sanjiv S. Chhoker
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 3, Pp 711-724 (2013)
Obesity-associated chronic inflammation contributes to metabolic dysfunction and propagates atherosclerosis. Recent evidence suggests that increased dietary cholesterol exacerbates inflammation in adipose tissue and liver, contributing to the proathe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6054837676dc51c0f8d7dfef537619fc
http://www.sciencedirect.com/science/article/pii/S0022227520419352
http://www.sciencedirect.com/science/article/pii/S0022227520419352
Autor:
Murray W. Huff, Jane Y. Edwards, Dawn E. Telford, Julia M. Assini, Brian G. Sutherland, Erin E. Mulvihill
Publikováno v:
Cardiovascular & Hematological Disorders-Drug Targets. 12:146-166
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4129f151b7ad58db324642ff6b8ccee
https://doi.org/10.2174/1871529x11202020146
https://doi.org/10.2174/1871529x11202020146
Autor:
Julie B. Koppes, Cynthia G. Sawyez, Murray W. Huff, Julia M. Assini, Maryam Khami, Alessandra S. DiMattia, Erin E. Mulvihill, Stewart C. Whitman, Brian G. Sutherland
Publikováno v:
Robarts Vascular Research Publications
Objective— Naringenin is a citrus flavonoid that potently inhibits the assembly and secretion of apolipoprotein B100–containing lipoproteins in cultured hepatocytes and improves the dyslipidemia and insulin resistance in a mouse model of the meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00261ec5a3c5fd7b3dfc9fa462419f70
https://doi.org/10.1161/atvbaha.109.201095
https://doi.org/10.1161/atvbaha.109.201095